Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1111/gcb.13548 |
Precision wildlife medicine: applications of the human-centred precision medicine revolution to species conservation | |
Whilde, Jenny1,2; Martindale, Mark Q.1,2; Duffy, David J.1,2,3 | |
2017-05-01 | |
发表期刊 | GLOBAL CHANGE BIOLOGY |
ISSN | 1354-1013 |
EISSN | 1365-2486 |
出版年 | 2017 |
卷号 | 23期号:5 |
文章类型 | Editorial Material |
语种 | 英语 |
国家 | USA; Ireland |
英文摘要 | The current species extinction crisis is being exacerbated by an increased rate of emergence of epizootic disease. Human-induced factors including habitat degradation, loss of biodiversity and wildlife population reductions resulting in reduced genetic variation are accelerating disease emergence. Novel, efficient and effective approaches are required to combat these epizootic events. Here, we present the case for the application of human precision medicine approaches to wildlife medicine in order to enhance species conservation efforts. We consider how the precision medicine revolution, coupled with the advances made in genomics, may provide a powerful and feasible approach to identifying and treating wildlife diseases in a targeted, effective and streamlined manner. A number of case studies of threatened species are presented which demonstrate the applicability of precision medicine to wildlife conservation, including sea turtles, amphibians and Tasmanian devils. These examples show how species conservation could be improved by using precision medicine techniques to determine novel treatments and management strategies for the specific medical conditions hampering efforts to restore population levels. Additionally, a precision medicine approach to wildlife health has in turn the potential to provide deeper insights into human health and the possibility of stemming and alleviating the impacts of zoonotic diseases. The integration of the currently emerging Precision Medicine Initiative with the concepts of EcoHealth (aiming for sustainable health of people, animals and ecosystems through transdisciplinary action research) and One Health (recognizing the intimate connection of humans, animal and ecosystem health and addressing a wide range of risks at the animal-human-ecosystem interface through a coordinated, collaborative, interdisciplinary approach) has great potential to deliver a deeper and broader interdisciplinary- based understanding of both wildlife and human diseases. |
英文关键词 | chytridiomycosis EcoHealth emerging disease environmental DNA (eDNA) epizootic disease fibropapillomatosis One Health systems medicine wildlife cancer wildlife disease |
领域 | 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000397800600005 |
WOS关键词 | ST-LAWRENCE ESTUARY ; INFECTIOUS-DISEASES ; TRANSMISSIBLE CANCER ; SYSTEMS MEDICINE ; GREEN TURTLES ; EBOLA-VIRUS ; ZIKA VIRUS ; BATRACHOCHYTRIUM-DENDROBATIDIS ; AMPHIBIAN CHYTRIDIOMYCOSIS ; PERSONALIZED MEDICINE |
WOS类目 | Biodiversity Conservation ; Ecology ; Environmental Sciences |
WOS研究方向 | Biodiversity & Conservation ; Environmental Sciences & Ecology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/17652 |
专题 | 气候变化 资源环境科学 |
作者单位 | 1.Univ Florida, Whitney Lab Marine Biosci, 9505 Ocean Shore Blvd, St Augustine, FL 32080 USA; 2.Univ Florida, Sea Turtle Hosp, 9505 Ocean Shore Blvd, St Augustine, FL 32080 USA; 3.Univ Coll Dublin, Syst Biol Ireland, Sci Link Bldg, Dublin 4, Ireland |
推荐引用方式 GB/T 7714 | Whilde, Jenny,Martindale, Mark Q.,Duffy, David J.. Precision wildlife medicine: applications of the human-centred precision medicine revolution to species conservation[J]. GLOBAL CHANGE BIOLOGY,2017,23(5). |
APA | Whilde, Jenny,Martindale, Mark Q.,&Duffy, David J..(2017).Precision wildlife medicine: applications of the human-centred precision medicine revolution to species conservation.GLOBAL CHANGE BIOLOGY,23(5). |
MLA | Whilde, Jenny,et al."Precision wildlife medicine: applications of the human-centred precision medicine revolution to species conservation".GLOBAL CHANGE BIOLOGY 23.5(2017). |
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