Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1126/science.aag0804 |
Industrial biomanufacturing: The future of chemical production | |
Clomburg, James M.1; Crumbley, Anna M.1; Gonzalez, Ramon1,2 | |
2017-01-06 | |
发表期刊 | SCIENCE
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ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2017 |
卷号 | 355期号:6320 |
文章类型 | Review |
语种 | 英语 |
国家 | USA |
英文摘要 | The current model for industrial chemical manufacturing employs large-scale megafacilities that benefit from economies of unit scale. However, this strategy faces environmental, geographical, political, and economic challenges associated with energy and manufacturing demands. We review how exploiting biological processes for manufacturing (i.e., industrial biomanufacturing) addresses these concerns while also supporting and benefiting from economies of unit number. Key to this approach is the inherent small scale and capital efficiency of bioprocesses and the ability of engineered biocatalysts to produce designer products at high carbon and energy efficiency with adjustable output, at high selectivity, and under mild process conditions. The biological conversion of single-carbon compounds represents a test bed to establish this paradigm, enabling rapid, mobile, and widespread deployment, access to remote and distributed resources, and adaptation to new and changing markets. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000391739900001 |
WOS关键词 | METHANOTROPH METHYLOMICROBIUM-BURYATENSE ; METHYLOSINUS-TRICHOSPORIUM OB3B ; COENZYME M REDUCTASE ; CRISPR-CAS SYSTEMS ; CARBON-DIOXIDE ; CLOSTRIDIUM-LJUNGDAHLII ; BIOSYNTHETIC-PATHWAY ; SACCHAROMYCES-CEREVISIAE ; ENERGY-CONSERVATION ; GAS FERMENTATION |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/195165 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Rice Univ, Dept Chem & Biomol Engn, Houston, TX 77005 USA; 2.Rice Univ, Dept Bioengn, Houston, TX USA |
推荐引用方式 GB/T 7714 | Clomburg, James M.,Crumbley, Anna M.,Gonzalez, Ramon. Industrial biomanufacturing: The future of chemical production[J]. SCIENCE,2017,355(6320). |
APA | Clomburg, James M.,Crumbley, Anna M.,&Gonzalez, Ramon.(2017).Industrial biomanufacturing: The future of chemical production.SCIENCE,355(6320). |
MLA | Clomburg, James M.,et al."Industrial biomanufacturing: The future of chemical production".SCIENCE 355.6320(2017). |
条目包含的文件 | 条目无相关文件。 |
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