GSTDTAP  > 地球科学
DOI10.1126/science.aal1988
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America
Patin, Etienne1,2,3; Lopez, Marie1,2,3; Grollemund, Rebecca4,5,6; Verdu, Paul7; Harmant, Christine1,2,3; Quach, Helene1,2,3; Laval, Guillaume1,2,3; Perry, George H.8,9; Barreiro, Luis B.10; Froment, Alain11; Heyer, Evelyne7; Massougbodji, Achille12,13; Fortes-Lima, Cesar7,14; Migot-Nabias, Florence15,16; Bellis, Gil17; Dugoujon, Jean-Michel14; Pereira, Joana B.18,19; Fernandes, Veronica18,19; Pereira, Luisa18,19,20; Van der Veen, Lolke21; Mouguiama-Daouda, Patrick21,22; Bustamante, Carlos D.23,24; Hombert, Jean-Marie21; Quintana-Murci, Lluis1,2,3
2017-05-05
发表期刊SCIENCE
ISSN0036-8075
EISSN1095-9203
出版年2017
卷号356期号:6337页码:543-546
文章类型Article
语种英语
国家France; England; USA; Canada; Benin; Portugal; Gabon
英文摘要

Bantu languages are spoken by about 310 million Africans, yet the genetic history of Bantu-speaking populations remains largely unexplored. We generated genomic data for 1318 individuals from 35 populations in western central Africa, where Bantu languages originated. We found that early Bantu speakers first moved southward, through the equatorial rainforest, before spreading toward eastern and southern Africa. We also found that genetic adaptation of Bantu speakers was facilitated by admixture with local populations, particularly for the HLA and LCT loci. Finally, we identified a major contribution of western central African Bantu speakers to the ancestry of African Americans, whose genomes present no strong signals of natural selection. Together, these results highlight the contribution of Bantu-speaking peoples to the complex genetic history of Africans and African Americans.


领域地球科学 ; 气候变化 ; 资源环境
收录类别SCI-E
WOS记录号WOS:000400545700039
WOS关键词ADMIXTURE ; GENOME ; ANCESTRY ; HISTORY ; EXPANSION ; SELECTION
WOS类目Multidisciplinary Sciences
WOS研究方向Science & Technology - Other Topics
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文献类型期刊论文
条目标识符http://119.78.100.173/C666/handle/2XK7JSWQ/195983
专题地球科学
资源环境科学
气候变化
作者单位1.Inst Pasteur, Human Evolut Genet, F-75015 Paris, France;
2.CNRS, URA3012, F-75015 Paris, France;
3.Inst Pasteur, Ctr Bioinformat Biostat & Integrat Biol, F-75015 Paris, France;
4.Univ Reading, Sch Biol Sci, Evolut Biol Grp, Reading RG6 6BX, Berks, England;
5.Univ Missouri, Dept English, Columbia, MO 65211 USA;
6.Univ Missouri, Dept Anthropol, Columbia, MO 65211 USA;
7.Univ Paris Diderot, Museum Natl Hist Nat, CNRS, UMR7206,Sorbonne Paris Cite, F-75016 Paris, France;
8.Penn State Univ, Dept Anthropol, University Pk, PA 16802 USA;
9.Penn State Univ, Dept Biol, University Pk, PA 16802 USA;
10.Univ Montreal, CHU St Justine, Ctr Rech, Montreal, PQ H3T 1C5, Canada;
11.Museum Natl Hist Nat, Inst Rech Dev, UMR 208, F-75005 Paris, France;
12.CERPAGE, Cotonou, Benin;
13.IRCB, 01 BP 188, Cotonou, Benin;
14.CNRS, UMR 5288, Anthropol Mol & Imagerie Synthese, Univ Paul Sabatier Toulouse 3, F-31073 Toulouse 3, France;
15.Inst Rech Dev, UMR 216, F-75006 Paris, France;
16.Univ Paris 05, Fac Pharm, Sorbonne Paris Cite, 1Commun Univ & Etablissements COMUE, F-75006 Paris, France;
17.Inst Natl Etud Demog, F-75020 Paris, France;
18.Univ Porto, I3S, P-4200135 Oporto, Portugal;
19.Univ Porto, Inst Patol & Imunol Mol, IPATIMUP, P-4200465 Oporto, Portugal;
20.Univ Porto, Fac Med, P-4200319 Oporto, Portugal;
21.CNRS, UMR 5596, Dynam Langage, Univ Lumiere Lyon 2, F-69007 Lyon, France;
22.Univ Omar Bongo, Lab Langue Culture & Cognit LCC, Libreville, Gabon;
23.Stanford Univ, Dept Genet, Stanford, CA 94305 USA;
24.Stanford Univ, Dept Biomed Data Sci, Stanford, CA 94305 USA
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GB/T 7714
Patin, Etienne,Lopez, Marie,Grollemund, Rebecca,et al. Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America[J]. SCIENCE,2017,356(6337):543-546.
APA Patin, Etienne.,Lopez, Marie.,Grollemund, Rebecca.,Verdu, Paul.,Harmant, Christine.,...&Quintana-Murci, Lluis.(2017).Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America.SCIENCE,356(6337),543-546.
MLA Patin, Etienne,et al."Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America".SCIENCE 356.6337(2017):543-546.
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