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| DOI | 10.1126/science.aan2954 |
| Comment on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport" | |
| Pellegrini, Luca | |
| 2017-07-21 | |
| 发表期刊 | SCIENCE
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| ISSN | 0036-8075 |
| EISSN | 1095-9203 |
| 出版年 | 2017 |
| 卷号 | 357期号:6348 |
| 文章类型 | Editorial Material |
| 语种 | 英语 |
| 国家 | England |
| 英文摘要 | O'Brien et al. (Research Article, 24 February 2017, eaag1789) report that the iron-sulfur cluster of primase has a redox role in enzyme activity. Their analysis is based on a partially misfolded structure of the iron-sulfur cluster domain of primase. In the correctly folded structure, two of the three tyrosines putatively involved in electron transfer, Y345 and Y347, contact the RNA/DNA helix, providing an alternative explanation for the data of O'Brien et al. |
| 领域 | 地球科学 ; 气候变化 ; 资源环境 |
| 收录类别 | SCI-E ; SSCI |
| WOS记录号 | WOS:000405901600003 |
| WOS关键词 | DOMAIN |
| WOS类目 | Multidisciplinary Sciences |
| WOS研究方向 | Science & Technology - Other Topics |
| URL | 查看原文 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/196502 |
| 专题 | 地球科学 资源环境科学 气候变化 |
| 作者单位 | Univ Cambridge, Dept Biochem, Cambridge, England |
| 推荐引用方式 GB/T 7714 | Pellegrini, Luca. Comment on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport"[J]. SCIENCE,2017,357(6348). |
| APA | Pellegrini, Luca.(2017).Comment on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport".SCIENCE,357(6348). |
| MLA | Pellegrini, Luca."Comment on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport"".SCIENCE 357.6348(2017). |
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