GSTDTAP  > 地球科学
DOI10.1126/science.aan2396
Comment on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport"
Baranovskiy, Andrey G.1; Babayeva, Nigar D.1; Zhang, Yinbo2; Blanco, Luis3; Pavlov, Youri I.1,4,5; Tahirov, Tahir H.1
2017-07-21
发表期刊SCIENCE
ISSN0036-8075
EISSN1095-9203
出版年2017
卷号357期号:6348
文章类型Editorial Material
语种英语
国家USA; Spain
英文摘要

O'Brien et al. (Research Article, 24 February 2017, eaag1789) proposed a novel mechanism of primase function based on redox activity of the iron-sulfur cluster buried inside the C-terminal domain of the large primase subunit (p58C). Serious problems in the experimental design and data interpretation raise concerns about the validity of the conclusions.


领域地球科学 ; 气候变化 ; 资源环境
收录类别SCI-E ; SSCI
WOS记录号WOS:000405901600001
WOS关键词C-TERMINAL DOMAIN ; CRYSTAL-STRUCTURE ; SUBUNIT ; REPLICATION ; MECHANISM ; PRIMER
WOS类目Multidisciplinary Sciences
WOS研究方向Science & Technology - Other Topics
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文献类型期刊论文
条目标识符http://119.78.100.173/C666/handle/2XK7JSWQ/196505
专题地球科学
资源环境科学
气候变化
作者单位1.Univ Nebraska Med Ctr, Fred & Pamela Buffett Canc Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA;
2.Univ Washington, Dept Immunol, Seattle, WA 98195 USA;
3.Ctr Biol Mol Severo Ochoa CSIC UAM, Madrid 28049, Spain;
4.Univ Nebraska Med Ctr, Dept Biochem & Mol Biol, Omaha, NE 68198 USA;
5.Univ Nebraska Med Ctr, Dept Pathol & Microbiol, Omaha, NE 68198 USA
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Baranovskiy, Andrey G.,Babayeva, Nigar D.,Zhang, Yinbo,et al. Comment on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport"[J]. SCIENCE,2017,357(6348).
APA Baranovskiy, Andrey G.,Babayeva, Nigar D.,Zhang, Yinbo,Blanco, Luis,Pavlov, Youri I.,&Tahirov, Tahir H..(2017).Comment on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport".SCIENCE,357(6348).
MLA Baranovskiy, Andrey G.,et al."Comment on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport"".SCIENCE 357.6348(2017).
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