Single-particle cryo-EM-How did it get here and where will it go

doi:10.1126/science.aat4346

GSTDTAP > 地球科学

DOI	10.1126/science.aat4346
	Single-particle cryo-EM-How did it get here and where will it go
	Cheng, Yifan
	2018-08-31
发表期刊	SCIENCE
ISSN	0036-8075
EISSN	1095-9203
出版年	2018
卷号	361 期号:6405 页码:876-+
文章类型	Review
语种	英语
国家	USA
英文摘要	Cryo-electron microscopy, or simply cryo-EM, refers mainly to three very different yet closely related techniques: electron crystallography, single-particle cryo-EM, and electron cryotomography. In the past few years, single-particle cryo-EM in particular has triggered a revolution in structural biology and has become a newly dominant discipline. This Review examines the fascinating story of its start and evolution over the past 40-plus years, delves into how and why the recent technological advances have been so groundbreaking, and briefly considers where the technique may be headed in the future.
领域	地球科学 ; 气候变化 ; 资源环境
收录类别	SCI-E
WOS记录号	WOS:000443547000028
WOS关键词	BEAM-INDUCED MOTION ; CRYOELECTRON MICROSCOPY ; ELECTRON-MICROSCOPY ; TRP CHANNELS ; ION-CHANNEL ; 3-DIMENSIONAL RECONSTRUCTION ; STRUCTURAL BIOLOGY ; RIBOSOMAL-SUBUNIT ; PROTEIN CRYSTALS ; CRYSTALLOGRAPHY
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/199481
专题	地球科学资源环境科学气候变化
作者单位	Univ Calif San Francisco, Dept Biochem & Biophys, Howard Hughes Med Inst, San Francisco, CA 94143 USA
推荐引用方式 GB/T 7714	Cheng, Yifan. Single-particle cryo-EM-How did it get here and where will it go[J]. SCIENCE,2018,361(6405):876-+.
APA	Cheng, Yifan.(2018).Single-particle cryo-EM-How did it get here and where will it go.SCIENCE,361(6405),876-+.
MLA	Cheng, Yifan."Single-particle cryo-EM-How did it get here and where will it go".SCIENCE 361.6405(2018):876-+.