Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1126/science.aaw8737 |
Transgenic Metarhizium rapidly kills mosquitoes in a malaria-endemic region of Burkina Faso | |
Lovett, Brian1; Bilgo, Etienne2; Millogo, Souro Abel2; Ouattarra, Abel Kader2; Sare, Issiaka2; Gnambani, Edounou Jacques2; Dabire, Roch K.2; Diabate, Abdoulaye2; Leger, Raymond J. St.1 | |
2019-05-31 | |
发表期刊 | SCIENCE |
ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2019 |
卷号 | 364期号:6443页码:894-+ |
文章类型 | Article |
语种 | 英语 |
国家 | USA; Burkina Faso |
英文摘要 | Malaria control efforts require implementation of new technologies that manage insecticide resistance. Metarhizium pingshaense provides an effective, mosquito-specific delivery system for potent insect-selective toxins. A semifield trial in a MosquitoSphere (a contained, near-natural environment) in Soumousso, a region of Burkina Faso where malaria is endemic, confirmed that the expression of an insect-specific toxin (Hybrid) increased fungal lethality and the likelihood that insecticide-resistant mosquitoes would be eliminated from a site. Also, as Hybrid-expressing M. pingshaense is effective at very low spore doses, its efficacy lasted longer than that of the unmodified Metarhizium. Deployment of transgenic Metarhizium against mosquitoes could (subject to appropriate registration) be rapid, with products that could synergistically integrate with existing chemical control strategies to avert insecticide resistance. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000469887900064 |
WOS关键词 | INSECTICIDE RESISTANCE ; ENTOMOPATHOGENIC FUNGUS ; PULSE-COMPRESSION ; SPECTRAL PHASE ; FEMTOSECOND ; DISPERSION ; RESOLUTION ; FIELD ; POLARIZATION ; INFECTION |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/201518 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Univ Maryland, Dept Entomol, College Pk, MD 20742 USA; 2.Inst Rech Sci Sante, Ctr Muraz, Bobo Dioulasso, Burkina Faso |
推荐引用方式 GB/T 7714 | Lovett, Brian,Bilgo, Etienne,Millogo, Souro Abel,et al. Transgenic Metarhizium rapidly kills mosquitoes in a malaria-endemic region of Burkina Faso[J]. SCIENCE,2019,364(6443):894-+. |
APA | Lovett, Brian.,Bilgo, Etienne.,Millogo, Souro Abel.,Ouattarra, Abel Kader.,Sare, Issiaka.,...&Leger, Raymond J. St..(2019).Transgenic Metarhizium rapidly kills mosquitoes in a malaria-endemic region of Burkina Faso.SCIENCE,364(6443),894-+. |
MLA | Lovett, Brian,et al."Transgenic Metarhizium rapidly kills mosquitoes in a malaria-endemic region of Burkina Faso".SCIENCE 364.6443(2019):894-+. |
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