Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1126/science.aaw7894 |
Organoids-on-a-chip | |
Park, Sunghee Estelle1; Georgescu, Andrei1; Huh, Dongeun1,2,3 | |
2019-06-07 | |
发表期刊 | SCIENCE
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ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2019 |
卷号 | 364期号:6444页码:960-965 |
文章类型 | Review |
语种 | 英语 |
国家 | USA |
英文摘要 | Recent studies have demonstrated an array of stem cell-derived, self-organizing miniature organs, termed organoids, that replicate the key structural and functional characteristics of their in vivo counterparts. As organoid technology opens up new frontiers of research in biomedicine, there is an emerging need for innovative engineering approaches for the production, control, and analysis of organoids and their microenvironment. In this Review, we explore organ-on-a-chip technology as a platform to fulfill this need and examine how this technology may be leveraged to address major technical challenges in organoid research. We also discuss emerging opportunities and future obstacles for the development and application of organoid-on-a-chip technology. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000482914100049 |
WOS关键词 | MODELING DEVELOPMENT ; GENERATION ; DISEASE ; NETWORKS ; BIOLOGY ; TISSUES |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/201590 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA; 2.Univ Penn, Perelman Sch Med, Inst Regenerat Med, Philadelphia, PA 19104 USA; 3.Univ Penn, NSF Sci & Technol Ctr Engn Mech, Philadelphia, PA 19104 USA |
推荐引用方式 GB/T 7714 | Park, Sunghee Estelle,Georgescu, Andrei,Huh, Dongeun. Organoids-on-a-chip[J]. SCIENCE,2019,364(6444):960-965. |
APA | Park, Sunghee Estelle,Georgescu, Andrei,&Huh, Dongeun.(2019).Organoids-on-a-chip.SCIENCE,364(6444),960-965. |
MLA | Park, Sunghee Estelle,et al."Organoids-on-a-chip".SCIENCE 364.6444(2019):960-965. |
条目包含的文件 | 条目无相关文件。 |
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