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DOI | 10.1126/science.aaw5181 |
Sequential replay of nonspatial task states in the human hippocampus | |
Schuck, Nicolas W.1,2,3,4; Niv, Yael3,4 | |
2019-06-28 | |
发表期刊 | SCIENCE
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ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2019 |
卷号 | 364期号:6447页码:1254-+ |
文章类型 | Article |
语种 | 英语 |
国家 | Germany; USA |
英文摘要 | Sequential neural activity patterns related to spatial experiences are "replayed" in the hippocampus of rodents during rest. We investigated whether replay of nonspatial sequences can be detected noninvasively in the human hippocampus. Participants underwent functional magnetic resonance imaging (fMRI) while resting after performing a decision-making task with sequential structure. Hippocampal fMRI patterns recorded at rest reflected sequentiality of previously experienced task states, with consecutive patterns corresponding to nearby states. Hippocampal sequentiality correlated with the fidelity of task representations recorded in the orbitofrontal cortex during decision-making, which were themselves related to better task performance. Our findings suggest that hippocampal replay may be important for building representations of complex, abstract tasks elsewhere in the brain and establish feasibility of investigating fast replay signals with fMRI. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000473271300040 |
WOS关键词 | MEDIAL TEMPORAL-LOBE ; ORBITOFRONTAL CORTEX ; MEMORY CONSOLIDATION ; COGNITIVE MAP ; SEQUENCES ; REPRESENTATIONS ; REACTIVATION ; RIPPLES ; FMRI ; CELLS |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/201752 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Max Planck Inst Human Dev, Max Planck Res Grp NeuroCode, Lentzeallee 94, D-14195 Berlin, Germany; 2.Max Planck Univ Coll London UCL, Ctr Computat Psychiat & Ageing Res, Berlin, Germany; 3.Princeton Univ, Princeton Neurosci Inst, Washington Rd, Princeton, NJ 08544 USA; 4.Princeton Univ, Dept Psychol, Washington Rd, Princeton, NJ 08544 USA |
推荐引用方式 GB/T 7714 | Schuck, Nicolas W.,Niv, Yael. Sequential replay of nonspatial task states in the human hippocampus[J]. SCIENCE,2019,364(6447):1254-+. |
APA | Schuck, Nicolas W.,&Niv, Yael.(2019).Sequential replay of nonspatial task states in the human hippocampus.SCIENCE,364(6447),1254-+. |
MLA | Schuck, Nicolas W.,et al."Sequential replay of nonspatial task states in the human hippocampus".SCIENCE 364.6447(2019):1254-+. |
条目包含的文件 | 条目无相关文件。 |
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