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DOI | 10.1126/science.aaw8231 |
Cell migration and axon guidance at the border between central and peripheral nervous system | |
Suter, Tracey A. C. S.1,2; Jaworski, Alexander1,2 | |
2019-08-30 | |
发表期刊 | SCIENCE
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ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2019 |
卷号 | 365期号:6456页码:881-+ |
文章类型 | Review |
语种 | 英语 |
国家 | USA |
英文摘要 | The central and peripheral nervous system (CNS and PNS, respectively) are composed of distinct neuronal and glial cell types with specialized functional properties. However, a small number of select cells traverse the CNS-PNS boundary and connect these two major subdivisions of the nervous system. This pattern of segregation and selective connectivity is established during embryonic development, when neurons and glia migrate to their destinations and axons project to their targets. Here, we provide an overview of the cellular and molecular mechanisms that control cell migration and axon guidance at the vertebrate CNS-PNS border. We highlight recent advances on how cell bodies and axons are instructed to either cross or respect this boundary, and present open questions concerning the development and plasticity of the CNS-PNS interface. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000483975800035 |
WOS关键词 | PIAL BASEMENT-MEMBRANE ; BOUNDARY CAP CELLS ; PNS TRANSITIONAL ZONE ; MOTOR-NEURON SOMATA ; SCHWANN-CELLS ; SPINAL-CORD ; BASAL LAMINA ; EXIT POINTS ; OLIGODENDROCYTE MIGRATION ; TRANSCRIPTION FACTOR |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/202194 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Brown Univ, Dept Neurosci, Div Biol & Med, Providence, RI 02912 USA; 2.Robert J & Nancy D Carney Inst Brain Sci, Providence, RI 02912 USA |
推荐引用方式 GB/T 7714 | Suter, Tracey A. C. S.,Jaworski, Alexander. Cell migration and axon guidance at the border between central and peripheral nervous system[J]. SCIENCE,2019,365(6456):881-+. |
APA | Suter, Tracey A. C. S.,&Jaworski, Alexander.(2019).Cell migration and axon guidance at the border between central and peripheral nervous system.SCIENCE,365(6456),881-+. |
MLA | Suter, Tracey A. C. S.,et al."Cell migration and axon guidance at the border between central and peripheral nervous system".SCIENCE 365.6456(2019):881-+. |
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