GSTDTAP  > 资源环境科学
DOI10.1038/s41467-018-06388-7
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils
Song, Yang1,2; Michaels, Thomas C. T.3,4; Ma, Qingming1,5; Liu, Zhou1,5; Yuan, Hao1,5; Takayama, Shuichi2; Knowles, Tuomas P. J.3,6; Shum, Ho Cheung1,5
2018-05-29
发表期刊NATURE COMMUNICATIONS
ISSN2041-1723
出版年2018
卷号9
文章类型Article
语种英语
国家Peoples R China; USA; England
英文摘要

Networks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that artificial networks of protein nanofibrils can induce controlled deformation and division of all-aqueous emulsion droplets with budding-like morphologies. We show that this process is driven by the difference in the immersional wetting energy of the nanofibril network, and that both the size and the number of the daughter droplets formed during division can be controlled by modulating the fibril concentration and the chemical properties of the fibril network. Our results demonstrate a route for achieving biomimetic division with synthetic self-assembling fibrils and offer an engineered approach to regulate the morphology of protein gels.


领域资源环境
收录类别SCI-E
WOS记录号WOS:000433298800001
WOS关键词VESICLES ; FABRICATION ; CELLS ; MODEL
WOS类目Multidisciplinary Sciences
WOS研究方向Science & Technology - Other Topics
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文献类型期刊论文
条目标识符http://119.78.100.173/C666/handle/2XK7JSWQ/204010
专题资源环境科学
作者单位1.Univ Hong Kong, Dept Mech Engn, Pokfulam 999077, Hong Kong, Peoples R China;
2.Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Atlanta, GA 30332 USA;
3.Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England;
4.Harvard Univ, Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA;
5.HKU SIRI, Shenzhen 518000, Peoples R China;
6.Univ Cambridge, Dept Phys, Cavendish Lab, JJ Thomson Ave, Cambridge CB3 0HE, England
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GB/T 7714
Song, Yang,Michaels, Thomas C. T.,Ma, Qingming,et al. Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils[J]. NATURE COMMUNICATIONS,2018,9.
APA Song, Yang.,Michaels, Thomas C. T..,Ma, Qingming.,Liu, Zhou.,Yuan, Hao.,...&Shum, Ho Cheung.(2018).Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.NATURE COMMUNICATIONS,9.
MLA Song, Yang,et al."Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils".NATURE COMMUNICATIONS 9(2018).
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