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DOI | 10.1038/s41467-018-06388-7 |
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils | |
Song, Yang1,2; Michaels, Thomas C. T.3,4; Ma, Qingming1,5; Liu, Zhou1,5; Yuan, Hao1,5; Takayama, Shuichi2; Knowles, Tuomas P. J.3,6; Shum, Ho Cheung1,5 | |
2018-05-29 | |
发表期刊 | NATURE COMMUNICATIONS
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ISSN | 2041-1723 |
出版年 | 2018 |
卷号 | 9 |
文章类型 | Article |
语种 | 英语 |
国家 | Peoples R China; USA; England |
英文摘要 | Networks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that artificial networks of protein nanofibrils can induce controlled deformation and division of all-aqueous emulsion droplets with budding-like morphologies. We show that this process is driven by the difference in the immersional wetting energy of the nanofibril network, and that both the size and the number of the daughter droplets formed during division can be controlled by modulating the fibril concentration and the chemical properties of the fibril network. Our results demonstrate a route for achieving biomimetic division with synthetic self-assembling fibrils and offer an engineered approach to regulate the morphology of protein gels. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000433298800001 |
WOS关键词 | VESICLES ; FABRICATION ; CELLS ; MODEL |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/204010 |
专题 | 资源环境科学 |
作者单位 | 1.Univ Hong Kong, Dept Mech Engn, Pokfulam 999077, Hong Kong, Peoples R China; 2.Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Atlanta, GA 30332 USA; 3.Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England; 4.Harvard Univ, Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA; 5.HKU SIRI, Shenzhen 518000, Peoples R China; 6.Univ Cambridge, Dept Phys, Cavendish Lab, JJ Thomson Ave, Cambridge CB3 0HE, England |
推荐引用方式 GB/T 7714 | Song, Yang,Michaels, Thomas C. T.,Ma, Qingming,et al. Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils[J]. NATURE COMMUNICATIONS,2018,9. |
APA | Song, Yang.,Michaels, Thomas C. T..,Ma, Qingming.,Liu, Zhou.,Yuan, Hao.,...&Shum, Ho Cheung.(2018).Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.NATURE COMMUNICATIONS,9. |
MLA | Song, Yang,et al."Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils".NATURE COMMUNICATIONS 9(2018). |
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