Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1038/s41467-018-08258-8 |
Cell-size dependent progression of the cell cycle creates homeostasis and flexibility of plant cell size | |
Jones, Angharad R.1; Forero-Vargas, Manuel1,4; Withers, Simon P.; Smith, Richard S.2; Traas, Jan3; Dewitte, Walter1; Murray, James A. H.1 | |
2019-01-17 | |
发表期刊 | NATURE COMMUNICATIONS
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ISSN | 2041-1723 |
出版年 | 2017 |
卷号 | 8 |
文章类型 | Article |
语种 | 英语 |
国家 | Wales; Germany; France; Colombia |
英文摘要 | Mean cell size at division is generally constant for specific conditions and cell types, but the mechanisms coupling cell growth and cell cycle control with cell size regulation are poorly understood in intact tissues. Here we show that the continuously dividing fields of cells within the shoot apical meristem of Arabidopsis show dynamic regulation of mean cell size dependent on developmental stage, genotype and environmental signals. We show cell size at division and cell cycle length is effectively predicted using a two-stage cell cycle model linking cell growth and two sequential cyclin dependent kinase (CDK) activities, and experimental results concur in showing that progression through both G1/S and G2/M is size dependent. This work shows that cell-autonomous co-ordination of cell growth and cell division previously observed in unicellular organisms also exists in intact plant tissues, and that cell size may be an emergent rather than directly determined property of cells. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000400155700001 |
WOS关键词 | FIBROBLASTS IN-VITRO ; SACCHAROMYCES-CEREVISIAE ; ARABIDOPSIS ; DIVISION ; KINASE ; GROWTH ; PROTEIN ; YEAST ; PROLIFERATION ; COORDINATION |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/204174 |
专题 | 资源环境科学 |
作者单位 | 1.Cardiff Univ, Cardiff Sch Biosci, Div Mol Biosci, Cardiff CF10 3AX, S Glam, Wales; 2.Max Planck Inst Plant Breeding Res, Dept Comparat Dev & Genet, D-50829 Cologne, Germany; 3.Univ Lyon, UCB Lyon 1, Lab Reprod Dev Plantes, INRA,CNRS,ENS Lyon, F-69364 Lyon 07, France; 4.Univ Ibague, Fac Ingn, Grp Invest D TEC, Ibague 730002, Colombia |
推荐引用方式 GB/T 7714 | Jones, Angharad R.,Forero-Vargas, Manuel,Withers, Simon P.,et al. Cell-size dependent progression of the cell cycle creates homeostasis and flexibility of plant cell size[J]. NATURE COMMUNICATIONS,2019,8. |
APA | Jones, Angharad R..,Forero-Vargas, Manuel.,Withers, Simon P..,Smith, Richard S..,Traas, Jan.,...&Murray, James A. H..(2019).Cell-size dependent progression of the cell cycle creates homeostasis and flexibility of plant cell size.NATURE COMMUNICATIONS,8. |
MLA | Jones, Angharad R.,et al."Cell-size dependent progression of the cell cycle creates homeostasis and flexibility of plant cell size".NATURE COMMUNICATIONS 8(2019). |
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