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DOI | 10.1038/s41467-019-08913-8 |
A cerebellar mechanism for learning prior distributions of time intervals | |
Narain, Devika1,2,3,4; Remington, Evan D.2; De Zeeuw, Chris I.3,4; Jazayeri, Mehrdad1,2 | |
2019-03-07 | |
发表期刊 | NATURE COMMUNICATIONS
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ISSN | 2041-1723 |
出版年 | 2018 |
卷号 | 9 |
文章类型 | Article |
语种 | 英语 |
国家 | USA; Netherlands |
英文摘要 | Knowledge about the statistical regularities of the world is essential for cognitive and sensorimotor function. In the domain of timing, prior statistics are crucial for optimal prediction, adaptation and planning. Where and how the nervous system encodes temporal statistics is, however, not known. Based on physiological and anatomical evidence for cerebellar learning, we develop a computational model that demonstrates how the cerebellum could learn prior distributions of time intervals and support Bayesian temporal estimation. The model shows that salient features observed in human Bayesian time interval estimates can be readily captured by learning in the cerebellar cortex and circuit level computations in the cerebellar deep nuclei. We test human behavior in two cerebellar timing tasks and find prior-dependent biases in timing that are consistent with the predictions of the cerebellar model. |
领域 | 资源环境 |
收录类别 | SCI-E ; SSCI |
WOS记录号 | WOS:000423790400003 |
WOS关键词 | PURKINJE-CELL ; SUPERIOR COLLICULUS ; DESCENDING PROJECTIONS ; LATERAL GENICULATE ; CLIMBING FIBERS ; DENTATE NUCLEUS ; NEURAL BASIS ; CORTEX ; TRACE ; PLASTICITY |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/204252 |
专题 | 资源环境科学 |
作者单位 | 1.MIT, Dept Brain & Cognit Sci, E25-618, Cambridge, MA 02139 USA; 2.MIT, McGovern Inst Brain Res, 77 Massachusetts Ave, Cambridge, MA 02139 USA; 3.Erasmus Med Univ, Dept Neurosci, NL-3015 CN Rotterdam, Netherlands; 4.Netherlands Inst Neurosci, NL-1105 BA Amsterdam, Netherlands |
推荐引用方式 GB/T 7714 | Narain, Devika,Remington, Evan D.,De Zeeuw, Chris I.,et al. A cerebellar mechanism for learning prior distributions of time intervals[J]. NATURE COMMUNICATIONS,2019,9. |
APA | Narain, Devika,Remington, Evan D.,De Zeeuw, Chris I.,&Jazayeri, Mehrdad.(2019).A cerebellar mechanism for learning prior distributions of time intervals.NATURE COMMUNICATIONS,9. |
MLA | Narain, Devika,et al."A cerebellar mechanism for learning prior distributions of time intervals".NATURE COMMUNICATIONS 9(2019). |
条目包含的文件 | 条目无相关文件。 |
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