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DOI | 10.1038/s41467-019-12890-3 |
Comparing frontal eye field and superior colliculus contributions to covert spatial attention | |
Bollimunta, Anil; Bogadhi, Amarender R.; Krauzlis, Richard J. | |
2019-10-30 | |
发表期刊 | NATURE COMMUNICATIONS
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ISSN | 2041-1723 |
出版年 | 2018 |
卷号 | 9 |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文摘要 | The causal roles of the frontal eye fields (FEF) and superior colliculus (SC) in spatial selective attention have not been directly compared. Reversible inactivation is an established method for testing causality but comparing results between FEF and SC is complicated by differences in size and morphology of the two brain regions. Here we exploited the fact that inactivation of FEF and SC also changes the metrics of saccadic eye movements, providing an independent benchmark for the strength of the causal manipulation. Using monkeys trained to covertly perform a visual motion-change detection task, we found that inactivation of either FEF or SC could cause deficits in attention task performance. However, SC-induced attention deficits were found with saccade changes half the size needed to get FEF-induced attention deficits. Thus, performance in visual attention tasks is vulnerable to loss of signals from either structure, but suppression of SC activity has a more devastating effect. |
领域 | 资源环境 |
收录类别 | SCI-E ; SSCI |
WOS记录号 | WOS:000443465100005 |
WOS关键词 | SUBUNIT MESSENGER-RNAS ; PREFRONTAL CORTEX ; TARGET SELECTION ; REVERSIBLE INACTIVATION ; NEURONAL MECHANISMS ; VISUAL-ATTENTION ; WORKING-MEMORY ; MOVEMENTS ; MONKEY ; MUSCIMOL |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/204623 |
专题 | 资源环境科学 |
作者单位 | NEI, Lab Sensorimotor Res, Bldg 10, Bethesda, MD 20892 USA |
推荐引用方式 GB/T 7714 | Bollimunta, Anil,Bogadhi, Amarender R.,Krauzlis, Richard J.. Comparing frontal eye field and superior colliculus contributions to covert spatial attention[J]. NATURE COMMUNICATIONS,2019,9. |
APA | Bollimunta, Anil,Bogadhi, Amarender R.,&Krauzlis, Richard J..(2019).Comparing frontal eye field and superior colliculus contributions to covert spatial attention.NATURE COMMUNICATIONS,9. |
MLA | Bollimunta, Anil,et al."Comparing frontal eye field and superior colliculus contributions to covert spatial attention".NATURE COMMUNICATIONS 9(2019). |
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