Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1289/EHP1699 |
Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California | |
Blount, Robert J.1,2; Pascopella, Lisa3; Catanzaro, Donald G.4; Barry, Pennan M.3; English, Paul B.5; Segal, Mark R.6; Flood, Jennifer3; Meltzer, Dan7; Jones, Brenda8; Balmes, John1,9; Nahid, Payam1 | |
2017-09-01 | |
发表期刊 | ENVIRONMENTAL HEALTH PERSPECTIVES
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ISSN | 0091-6765 |
EISSN | 1552-9924 |
出版年 | 2017 |
卷号 | 125期号:9 |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文摘要 | BACKGROUND: Ambient air pollution and tuberculosis (TB) have an impact on public health worldwide, yet associations between the two remain uncertain. OBJECTIVE: We determined the impact of residential traffic on mortality during treatment of active TB. METHODS: From 2000-2012, we enrolled 32,875 patients in California with active TB and followed them throughout treatment. We obtained patient data from the California Tuberculosis Registry and calculated traffic volumes and traffic densities in 100- to 400-m radius buffers around residential addresses. We used Cox models to determine mortality hazard ratios, controlling for demographic, socioeconomic, and clinical potential confounders. We categorized traffic exposures as quintiles and determined trends using Wald tests. RESULTS: Participants contributed 22,576 person-years at risk. There were 2,305 deaths during treatment for a crude mortality rate of 1,021 deaths per 10,000 person-years. Traffic volumes and traffic densities in all buffers around patient residences were associated with increased mortality during TB treatment, although the findings were not statistically significant in all buffers. As the buffer size decreased, fifth-quintile mortality hazards increased, and trends across quintiles of traffic exposure became more statistically significant. Increasing quintiles of nearest-road traffic volumes in the 100-m buffer were associated with 3%, 14%, 19%, and 28% increased risk of death during TB treatment [first quintile, referent; second quintile hazard ratio (HR)=1.03 [95% confidence interval (CI): 0.86, 1.25]; third quintile HR=1.14 (95% CI: 0.95, 1.37); fourth quintile HR=1.19 (95% CI: 0.99, 1.43); fifth quintile HR=1.28 (95% CI: 1.07, 1.53), respectively; p-trend=0.002]. CONCLUSIONS: Residential proximity to road traffic volumes and traffic density were associated with increased all-cause mortality in patients undergoing treatment for active tuberculosis even after adjusting for multiple demographic, socioeconomic, and clinical factors, suggesting that TB patients are susceptible to the adverse health effects of traffic-related air pollution. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000461478500006 |
WOS类目 | Environmental Sciences ; Public, Environmental & Occupational Health ; Toxicology |
WOS研究方向 | Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Toxicology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/22458 |
专题 | 资源环境科学 |
作者单位 | 1.Univ Calif San Francisco, Div Pulm & Crit Care Med, Mission Hall 5th Floor,Box 0632,550 16th St, San Francisco, CA 94143 USA; 2.Univ Calif San Francisco, Div Pediat Pulmonol, San Francisco, CA 94143 USA; 3.Calif Dept Publ Hlth, TB Control Branch, Richmond, CA USA; 4.Univ Arkansas, Dept Biol Sci, Fayetteville, AR 72701 USA; 5.Calif Dept Publ Hlth, Environm Hlth Invest Branch, Richmond, CA USA; 6.Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA; 7.Publ Hlth Inst, Calif Environm Hlth Tracking Program, Oakland, CA USA; 8.Univ Southern Calif, Div Infect Dis, Los Angeles, CA USA; 9.Univ Calif Berkeley, Environm Hlth Sci, Berkeley, CA 94720 USA |
推荐引用方式 GB/T 7714 | Blount, Robert J.,Pascopella, Lisa,Catanzaro, Donald G.,et al. Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California[J]. ENVIRONMENTAL HEALTH PERSPECTIVES,2017,125(9). |
APA | Blount, Robert J..,Pascopella, Lisa.,Catanzaro, Donald G..,Barry, Pennan M..,English, Paul B..,...&Nahid, Payam.(2017).Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California.ENVIRONMENTAL HEALTH PERSPECTIVES,125(9). |
MLA | Blount, Robert J.,et al."Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California".ENVIRONMENTAL HEALTH PERSPECTIVES 125.9(2017). |
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