Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1289/EHP137 |
Ambient Air Pollutant Exposures and Hospitalization for Kawasaki Disease in Taiwan: A Case-Crossover Study (2000-2010) | |
Jung, Chau-Ren1,2; Chen, Wei-Ting3; Lin, Yu-Ting1,2; Hwang, Bing-Fang1 | |
2017-04-01 | |
发表期刊 | ENVIRONMENTAL HEALTH PERSPECTIVES
![]() |
ISSN | 0091-6765 |
EISSN | 1552-9924 |
出版年 | 2017 |
卷号 | 125期号:4 |
文章类型 | Article |
语种 | 英语 |
国家 | Taiwan |
英文摘要 | Background: Kawasaki disease (KD) is an acute and multi-systemic vasculitis that occurs -predominantly in infants and young children. Although the etiological agent of KD remains unclear, limited studies have reported that windborne environmental factors may trigger KD. Objectives: We conducted a time-stratified case-crossover study to assess the associations between air pollutants and KD in Taiwan. Methods: We identified children < 5 years old with a diagnosis of KD from the Longitudinal Health Insurance Database 2000 (LHID2000) between 2000 and 2010. We obtained data regarding carbon monoxide (CO), nitrogen dioxide (NO2), ozone (O-3), particulate matter with aerodynamic diameter < 10 mu m (PM10), and sulfate dioxide (SO2) from 70 monitoring stations and used inverse distance weighting to calculate average daily exposures for the residential postal code of each case. We performed conditional logistic regression to estimate associations between KD and each air pollutant according to interquartile range (IQR) increases and quartiles of exposure on the day of hospitalization versus 3-4 reference days during the same month for each case. Additionally, we estimated associations with single-day exposures lagged 1-2days. Results: We identified 695 KD hospital admissions during the study period. An IQR increase (28.73ppb) of O-3 was positively associated with KD after adjusting for temperature, humidity, northward wind, and eastward wind [adjusted odds ratio= 1.21; 95% confidence interval (CI): 1.01, 1.44]. There were no significant associations between KD and CO, NO2, PM10, or SO2. The association with O-3 was limited to exposure on the day of hospitalization and to exposure during the summer months (June-August). Conclusions: Our results provide new evidence that exposure to O-3 may increase the risk of KD in children. However, further investigation is needed to confirm the association and identify a potential biological mechanism. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000397904400029 |
WOS关键词 | CORONARY-ARTERY ; EPIDEMIOLOGIC FEATURES ; INCREASED RISK ; OZONE ; HEALTH ; ASSOCIATION ; MORTALITY ; TEMPERATURE ; STROKE ; YOUNG |
WOS类目 | Environmental Sciences ; Public, Environmental & Occupational Health ; Toxicology |
WOS研究方向 | Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Toxicology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/23227 |
专题 | 资源环境科学 |
作者单位 | 1.China Med Univ, Dept Occupat Safety & Hlth, Coll Publ Hlth, 91 Hsueh Shih Rd, Taichung 40402, Taiwan; 2.China Med Univ, Coll Publ Hlth, Dept Publ Hlth, Taichung, Taiwan; 3.Natl Taiwan Univ, Dept Atmospher Sci, Taipei, Taiwan |
推荐引用方式 GB/T 7714 | Jung, Chau-Ren,Chen, Wei-Ting,Lin, Yu-Ting,et al. Ambient Air Pollutant Exposures and Hospitalization for Kawasaki Disease in Taiwan: A Case-Crossover Study (2000-2010)[J]. ENVIRONMENTAL HEALTH PERSPECTIVES,2017,125(4). |
APA | Jung, Chau-Ren,Chen, Wei-Ting,Lin, Yu-Ting,&Hwang, Bing-Fang.(2017).Ambient Air Pollutant Exposures and Hospitalization for Kawasaki Disease in Taiwan: A Case-Crossover Study (2000-2010).ENVIRONMENTAL HEALTH PERSPECTIVES,125(4). |
MLA | Jung, Chau-Ren,et al."Ambient Air Pollutant Exposures and Hospitalization for Kawasaki Disease in Taiwan: A Case-Crossover Study (2000-2010)".ENVIRONMENTAL HEALTH PERSPECTIVES 125.4(2017). |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论