Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1289/EHP494 |
Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study | |
Pun, Vivian C.; Manjourides, Justin; Suh, Helen | |
2017-03-01 | |
发表期刊 | ENVIRONMENTAL HEALTH PERSPECTIVES
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ISSN | 0091-6765 |
EISSN | 1552-9924 |
出版年 | 2017 |
卷号 | 125期号:3 |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文摘要 | Background: Ambient fine particulate matter (PM2.5) is among the most prevalent sources of environmentally induced inflammation and oxidative stress, both of which are implicated in the pathogenesis of most mental disorders. Evidence, however, concerning the impact of PM2.5 on mental health is just emerging. Objective: We examined the association between PM2.5 and current level of depressive and anxiety symptoms using a nationally representative probability sample (n = 4,008) of older, community-dwelling individuals living across the United States (the National Social Life, Health and Aging project). Methods: Mental health was evaluated using validated, standardized questionnaires and clinically relevant cases were identified using well-established cutoffs; daily PM2.5 estimates were obtained using spatio-temporal models. We used generalized linear mixed models, adjusting for potential confounders, and explored effect modification. Results: An increase in PM2.5 was significantly associated with anxiety symptoms, with the largest increase for 180-days moving average (OR = 1.61; 95% CI: 1.35, 1.92) after adjusting for socio-economic measures (SES); PM2.5 was positively associated with depressive symptoms, and significantly for 30-day moving average (OR = 1.16; 95% CI: 1.05, 1.29) upon SES adjustment. The observed associations were enhanced among individuals who had low SES and history of comorbidity. When considering mental health as chronic conditions, PM2.5 was significantly associated with incident depressive symptoms for all exposure windows examined, but with incident anxiety symptoms only for shorter exposure windows, which may be due to a drop in power resulting from the decreased between-subject variability in chronic PM2.5 exposure. Conclusion: PM2.5 was associated with depressive and anxiety symptoms, with associations the strongest among individuals with lower SES or among those with certain health-related characteristics. |
领域 | 资源环境 |
收录类别 | SCI-E ; SSCI |
WOS记录号 | WOS:000395714400013 |
WOS关键词 | EMERGENCY-DEPARTMENT VISITS ; AMERICAN-HEART-ASSOCIATION ; PARTICULATE MATTER ; OXIDATIVE STRESS ; CARDIOVASCULAR-DISEASE ; HOSPITAL ANXIETY ; UNITED-STATES ; DISORDERS ; HEALTH ; INFLAMMATION |
WOS类目 | Environmental Sciences ; Public, Environmental & Occupational Health ; Toxicology |
WOS研究方向 | Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Toxicology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/24092 |
专题 | 资源环境科学 |
作者单位 | Northeastern Univ, Dept Hlth Sci, Boston, MA 02115 USA |
推荐引用方式 GB/T 7714 | Pun, Vivian C.,Manjourides, Justin,Suh, Helen. Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study[J]. ENVIRONMENTAL HEALTH PERSPECTIVES,2017,125(3). |
APA | Pun, Vivian C.,Manjourides, Justin,&Suh, Helen.(2017).Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study.ENVIRONMENTAL HEALTH PERSPECTIVES,125(3). |
MLA | Pun, Vivian C.,et al."Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study".ENVIRONMENTAL HEALTH PERSPECTIVES 125.3(2017). |
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