The Importance of Genetic Redundancy in Evolution

doi:10.1016/j.tree.2020.04.009

GSTDTAP > 资源环境科学

DOI	10.1016/j.tree.2020.04.009
	The Importance of Genetic Redundancy in Evolution
	Áki J. Láruson:Sam Yeaman:Katie E. Lotterhos
	2020-05-18
发表期刊	Trends in Ecology & Evolution\
出版年	2020
英文摘要	Genetic redundancy has been defined in many different ways at different levels of biological organization. Here, we briefly review the general concept of redundancy and focus on the evolutionary importance of redundancy in terms of the number of genotypes that give rise to the same phenotype. We discuss the challenges in determining redundancy empirically, with published experimental examples, and demonstrate the use of the C-score metric to quantify redundancy in evolution studies. We contrast the implicit assumptions of redundancy in quantitative versus population genetic models, show how this contributes to signatures of allele frequency shifts, and highlight how the rapid accumulation of genome-wide association data provides an avenue for further understanding the prevalence and role of redundancy in evolution.
领域	资源环境
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文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/267685
专题	资源环境科学
推荐引用方式 GB/T 7714	Áki J. Láruson:Sam Yeaman:Katie E. Lotterhos. The Importance of Genetic Redundancy in Evolution[J]. Trends in Ecology & Evolution\,2020.
APA	Áki J. Láruson:Sam Yeaman:Katie E. Lotterhos.(2020).The Importance of Genetic Redundancy in Evolution.Trends in Ecology & Evolution\.
MLA	Áki J. Láruson:Sam Yeaman:Katie E. Lotterhos."The Importance of Genetic Redundancy in Evolution".Trends in Ecology & Evolution\ (2020).