Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1289/EHP5907 |
Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study | |
Mahdi Sheikh; Hossein Poustchi; Akram Pourshams; Masoud Khoshnia; Abdolsamad Gharavi; Mahdi Zahedi; Gholamreza Roshandel; Sadaf G. Sepanlou; Abdolreza Fazel; Maryam Hashemian; Behrooz Abaei; Masoud Sotoudeh; Arash Nikmanesh; Shahin Merat; Arash Etemadi; Siavosh Nasseri Moghaddam; Farhad Islami; Farin Kamangar; Paul D. Pharoah; Sanford M. Dawsey; Christian C. Abnet; Paolo Boffetta; Paul Brennan; Reza Malekzadeh | |
2020-06-17 | |
发表期刊 | Environmental Health Perspectives |
出版年 | 2020 |
英文摘要 | AbstractBackground:Three billion people burn nonclean fuels for household purposes. Limited evidence suggests a link between household fuel use and gastrointestinal (GI) cancers. Objectives:We investigated the relationship between indoor burning of biomass, kerosene, and natural gas with the subsequent risk of GI cancers. Methods:During the period 2004–2008, a total of 50,045 Iranian individuals 40–75 years of age were recruited to this prospective population-based cohort. Upon enrollment, validated data were collected on demographics, lifestyle, and exposures, including detailed data on lifetime household use of different fuels and stoves. The participants were followed through August 2018 with loss. Results:During the follow-up, 962 participants developed GI cancers. In comparison with using predominantly gas in the recent 20-y period, using predominantly biomass was associated with higher risks of esophageal [hazard ratio (HR): 1.89; 95% confidence interval (CI): 1.02, 3.50], and gastric HR: 1.83; 95% CI: 1.01, 3.31) cancers, whereas using predominantly kerosene was associated with higher risk of esophageal cancer (HR: 1.84; 95% CI: 1.10, 3.10). Lifetime duration of biomass burning for both cooking and house heating (exclusive biomass usage) using heating-stoves without chimney was associated with higher risk of GI cancers combined (10-y HR: 1.14; 95% CI: 1.07, 1.21), esophageal (10-y HR: 1.19; 95% CI: 1.08, 1.30), gastric (10-y HR: 1.11; 95% CI: 1.00, 1.23), and colon (10-y HR: 1.26; 95% CI: 1.03, 1.54) cancers. The risks of GI cancers combined, esophageal cancer, and gastric cancer were lower when biomass was burned using chimney-equipped heating-stoves (strata difference , 0.003, and 0.094, respectively). Duration of exclusive kerosene burning using heating-stoves without chimney was associated with higher risk of GI cancers combined (10-y HR: 1.05; 95% CI: 1.00, 1.11), and esophageal cancer (10-y HR: 1.14; 95% CI: 1.04, 1.26). Discussion:Household burning of biomass or kerosene, especially without a chimney, was associated with higher risk of some digestive cancers. Using chimney-equipped stoves and replacing these fuels with natural gas may be useful interventions to reduce the burden of GI cancers worldwide. https://doi.org/10.1289/EHP5907 |
领域 | 资源环境 |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/276507 |
专题 | 资源环境科学 |
推荐引用方式 GB/T 7714 | Mahdi Sheikh,Hossein Poustchi,Akram Pourshams,et al. Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study[J]. Environmental Health Perspectives,2020. |
APA | Mahdi Sheikh.,Hossein Poustchi.,Akram Pourshams.,Masoud Khoshnia.,Abdolsamad Gharavi.,...&Reza Malekzadeh.(2020).Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study.Environmental Health Perspectives. |
MLA | Mahdi Sheikh,et al."Household Fuel Use and the Risk of Gastrointestinal Cancers: The Golestan Cohort Study".Environmental Health Perspectives (2020). |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论