Microfluidic electrochemistry for single-electron transfer redox-neutral reactions

doi:10.1126/science.aba3823

GSTDTAP > 气候变化

DOI	10.1126/science.aba3823
	Microfluidic electrochemistry for single-electron transfer redox-neutral reactions
	Yiming Mo; Zhaohong Lu; Girish Rughoobur; Prashant Patil; Neil Gershenfeld; Akintunde I. Akinwande; Stephen L. Buchwald; Klavs F. Jensen
	2020-06-19
发表期刊	Science
出版年	2020
英文摘要	In principle, electrochemistry is an ideal method for radical coupling: One precursor oxidized at the anode pairs up with a counterpart that has been reduced at the cathode. The trouble is that either or both coupling partners might not stay stable long enough to meet in the middle. Mo et al. resolved this issue by closely spacing the electrodes in a microfluidics platform (see the Perspective by Liu et al. ). They showcase coupling of dicyanobenzene as the cathodic radical precursor with a variety of oxidatively generated partners. Science , this issue p. [1352][1]; see also p. [1312][2] Electrochemistry offers opportunities to promote single-electron transfer (SET) redox-neutral chemistries similar to those recently discovered using visible-light photocatalysis but without the use of an expensive photocatalyst. Herein, we introduce a microfluidic redox-neutral electrochemistry (μRN-eChem) platform that has broad applicability to SET chemistry, including radical-radical cross-coupling, Minisci-type reactions, and nickel-catalyzed C(sp2)–O cross-coupling. The cathode and anode simultaneously generate the corresponding reactive intermediates, and selective transformation is facilitated by the rapid molecular diffusion across a microfluidic channel that outpaces the decomposition of the intermediates. μRN-eChem was shown to enable a two-step gram-scale electrosynthesis of a nematic liquid crystal compound, demonstrating its practicality. [1]: /lookup/doi/10.1126/science.aba3823 [2]: /lookup/doi/10.1126/science.abc2985
领域	气候变化 ; 资源环境
URL	查看原文
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/276696
专题	气候变化资源环境科学
推荐引用方式 GB/T 7714	Yiming Mo,Zhaohong Lu,Girish Rughoobur,et al. Microfluidic electrochemistry for single-electron transfer redox-neutral reactions[J]. Science,2020.
APA	Yiming Mo.,Zhaohong Lu.,Girish Rughoobur.,Prashant Patil.,Neil Gershenfeld.,...&Klavs F. Jensen.(2020).Microfluidic electrochemistry for single-electron transfer redox-neutral reactions.Science.
MLA	Yiming Mo,et al."Microfluidic electrochemistry for single-electron transfer redox-neutral reactions".Science (2020).