Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals

doi:10.1038/s41586-020-2271-3

GSTDTAP > 地球科学

DOI	10.1038/s41586-020-2271-3
	Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals
	Grishin, Evgeni 1; Malamud, Uri 1; Perets, Hagai B.1; Wandel, Oliver 2; Schaefer, Christoph M.2
	2020-04-01
发表期刊	NATURE
ISSN	0028-0836
EISSN	1476-4687
出版年	2020
文章类型	Article;Early Access
语种	英语
国家	Peoples R China
英文关键词	The ongoing outbreak of coronavirus disease 2019 (COVID-19) has spread rapidly on a global scale. Although it is clear that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted through human respiratory droplets and direct contact, the potential for aerosol transmission is poorly understood(1-3). Here we investigated the aerodynamic nature of SARS-CoV-2 by measuring viral RNA in aerosols in different areas of two Wuhan hospitals during the outbreak of COVID-19 in February and March 2020. The concentration of SARS-CoV-2 RNA in aerosols that was detected in isolation wards and ventilated patient rooms was very low, but it was higher in the toilet areas used by the patients. Levels of airborne SARS-CoV-2 RNA in the most public areas was undetectable, except in two areas that were prone to crowding this increase was possibly due to individuals infected with SARS-CoV-2 in the crowd. We found that some medical staff areas initially had high concentrations of viral RNA with aerosol size distributions that showed peaks in the submicrometre and/or supermicrometre regions however, these levels were reduced to undetectable levels after implementation of rigorous sanitization procedures. Although we have not established the infectivity of the virus detected in these hospital areas, we propose that SARS-CoV-2 may have the potential to be transmitted through aerosols. Our results indicate that room ventilation, open space, sanitization of protective apparel, and proper use and disinfection of toilet areas can effectively limit the concentration of SARS-CoV-2 RNA in aerosols. Future work should explore the infectivity of aerosolized virus. Aerodynamic analysis of SARS-CoV-2 RNA in two hospitals in Wuhan indicates that SARS-CoV-2 may have the potential to be transmitted through aerosols, although the infectivity of the virus RNA was not established in this study.
领域	地球科学 ; 气候变化 ; 资源环境
收录类别	SCI-E
WOS记录号	WOS:000541051000001
WOS关键词	AIRBORNE TRANSMISSION ; CORONAVIRUS
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/281283
专题	地球科学资源环境科学气候变化
作者单位	1.Technion Israel Inst Technol, Phys Dept, Haifa, Israel; 2.Eberhard Karls Univ Tubingen, Inst Astron & Astrophys, Tubingen, Germany
推荐引用方式 GB/T 7714	Grishin, Evgeni,Malamud, Uri,Perets, Hagai B.,et al. Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals[J]. NATURE,2020.
APA	Grishin, Evgeni,Malamud, Uri,Perets, Hagai B.,Wandel, Oliver,&Schaefer, Christoph M..(2020).Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals.NATURE.
MLA	Grishin, Evgeni,et al."Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals".NATURE (2020).