Introductions and early spread of SARS-CoV-2 in the New York City area

doi:10.1126/science.abc1917

GSTDTAP > 气候变化

DOI	10.1126/science.abc1917
	Introductions and early spread of SARS-CoV-2 in the New York City area
	Ana S. Gonzalez-Reiche; Matthew M. Hernandez; Mitchell J. Sullivan; Brianne Ciferri; Hala Alshammary; Ajay Obla; Shelcie Fabre; Giulio Kleiner; Jose Polanco; Zenab Khan; Bremy Alburquerque; Adriana van de Guchte; Jayeeta Dutta; Nancy Francoeur; Betsaida Salom Melo; Irina Oussenko; Gintaras Deikus; Juan Soto; Shwetha Hara Sridhar; Ying-Chih Wang; Kathryn Twyman; Andrew Kasarskis; Deena R. Altman; Melissa Smith; Robert Sebra; Judith Aberg; Florian Krammer; Adolfo García-Sastre; Marta Luksza; Gopi Patel; Alberto Paniz-Mondolfi; Melissa Gitman; Emilia Mia Sordillo; Viviana Simon; Harm van Bakel
	2020-07-17
发表期刊	Science
出版年	2020
英文摘要	Deaths caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New York City (NYC) during the spring of 2020 have vastly exceeded those reported in China and many other countries. What were the early events that led to such a severe outbreak? Gonzalez-Reiche et al. sampled some of the early patients seeking assistance in February and March of 2020 at the Mount Sinai Health System. Phylogenetic analysis of virus sequences in these people, who were drawn from across NYC, showed that the virus had been independently introduced many times from Europe and elsewhere in the United States. Subsequent clusters of community transmission occurred. The focus of infection in NYC is a marker of the role this city plays as a two-way hub for human movement. Science this issue p. [297][1] New York City (NYC) has emerged as one of the epicenters of the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. To identify the early transmission events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus that causes coronavirus disease 2019 (COVID-19) in patients seeking care at the Mount Sinai Health System. Phylogenetic analysis of 84 distinct SARS-CoV-2 genomes indicates multiple, independent, but isolated introductions mainly from Europe and other parts of the United States. Moreover, we found evidence for community transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different neighborhoods of the city. [1]: /lookup/doi/10.1126/science.abc1917
领域	气候变化 ; 资源环境
URL	查看原文
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文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/284349
专题	气候变化资源环境科学
推荐引用方式 GB/T 7714	Ana S. Gonzalez-Reiche,Matthew M. Hernandez,Mitchell J. Sullivan,et al. Introductions and early spread of SARS-CoV-2 in the New York City area[J]. Science,2020.
APA	Ana S. Gonzalez-Reiche.,Matthew M. Hernandez.,Mitchell J. Sullivan.,Brianne Ciferri.,Hala Alshammary.,...&Harm van Bakel.(2020).Introductions and early spread of SARS-CoV-2 in the New York City area.Science.
MLA	Ana S. Gonzalez-Reiche,et al."Introductions and early spread of SARS-CoV-2 in the New York City area".Science (2020).