Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California

doi:10.1126/science.abb9263

GSTDTAP > 气候变化

DOI	10.1126/science.abb9263
	Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California
	Xianding Deng; Wei Gu; Scot Federman; Louis du Plessis; Oliver G. Pybus; Nuno R. Faria; Candace Wang; Guixia Yu; Brian Bushnell; Chao-Yang Pan; Hugo Guevara; Alicia Sotomayor-Gonzalez; Kelsey Zorn; Allan Gopez; Venice Servellita; Elaine Hsu; Steve Miller; Trevor Bedford; Alexander L. Greninger; Pavitra Roychoudhury; Lea M. Starita; Michael Famulare; Helen Y. Chu; Jay Shendure; Keith R. Jerome; Catie Anderson; Karthik Gangavarapu; Mark Zeller; Emily Spencer; Kristian G. Andersen; Duncan MacCannell; Clinton R. Paden; Yan Li; Jing Zhang; Suxiang Tong; Gregory Armstrong; Scott Morrow; Matthew Willis; Bela T. Matyas; Sundari Mase; Olivia Kasirye; Maggie Park; Godfred Masinde; Curtis Chan; Alexander T. Yu; Shua J. Chai; Elsa Villarino; Brandon Bonin; Debra A. Wadford; Charles Y. Chiu
	2020-07-31
发表期刊	Science
出版年	2020
英文摘要	Genome sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreaks is valuable for tracing the sources and perhaps for drawing lessons about preventing future outbreaks. Genomic analysis by Deng et al. revealed that Northern California experienced a complex series of introductions of the virus, deriving not only from state-to-state transmission but also from international travel by air and ship. The study highlights the importance of being able to rapidly test and trace contacts of positive cases to enable swift control. Science , this issue p. [582][1] The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, with >365,000 cases in California as of 17 July 2020. We investigated the genomic epidemiology of SARS-CoV-2 in Northern California from late January to mid-March 2020, using samples from 36 patients spanning nine counties and the Grand Princess cruise ship. Phylogenetic analyses revealed the cryptic introduction of at least seven different SARS-CoV-2 lineages into California, including epidemic WA1 strains associated with Washington state, with lack of a predominant lineage and limited transmission among communities. Lineages associated with outbreak clusters in two counties were defined by a single base substitution in the viral genome. These findings support contact tracing, social distancing, and travel restrictions to contain the spread of SARS-CoV-2 in California and other states. [1]: /lookup/doi/10.1126/science.abb9263
领域	气候变化 ; 资源环境
URL	查看原文
引用统计	被引频次：155[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/286876
专题	气候变化资源环境科学
推荐引用方式 GB/T 7714	Xianding Deng,Wei Gu,Scot Federman,et al. Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California[J]. Science,2020.
APA	Xianding Deng.,Wei Gu.,Scot Federman.,Louis du Plessis.,Oliver G. Pybus.,...&Charles Y. Chiu.(2020).Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California.Science.
MLA	Xianding Deng,et al."Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California".Science (2020).