WUSCHEL triggers innate antiviral immunity in plant stem cells

doi:10.1126/science.abb7360

GSTDTAP > 气候变化

DOI	10.1126/science.abb7360
	WUSCHEL triggers innate antiviral immunity in plant stem cells
	Haijun Wu; Xiaoya Qu; Zhicheng Dong; Linjie Luo; Chen Shao; Joachim Forner; Jan U. Lohmann; Meng Su; Mengchu Xu; Xiaobin Liu; Lei Zhu; Jian Zeng; Sumei Liu; Zhaoxia Tian; Zhong Zhao
	2020-10-09
发表期刊	Science
出版年	2020
英文摘要	The meristem, the collection of stem cells that builds plants, is resistant to viral infection. Wu et al. now show that WUSCHEL, a transcription factor that helps to sustain stem cell production in the shoot apical meristem of Arabidopsis , also protects that stem cell domain from viruses. WUSCHEL inhibited viral protein synthesis by repressing methyltransferases that regulate ribosomal RNA processing and ribosome stability. Science , this issue p. [227][1] Stem cells in plants constantly supply daughter cells to form new organs and are expected to safeguard the integrity of the cells from biological invasion. Here, we show how stem cells of the Arabidopsis shoot apical meristem and their nascent daughter cells suppress infection by cucumber mosaic virus (CMV). The stem cell regulator WUSCHEL responds to CMV infection and represses virus accumulation in the meristem central and peripheral zones. WUSCHEL inhibits viral protein synthesis by repressing the expression of plant S -adenosyl-l-methionine–dependent methyltransferases, which are involved in ribosomal RNA processing and ribosome stability. Our results reveal a conserved strategy in plants to protect stem cells against viral intrusion and provide a molecular basis for WUSCHEL-mediated broad-spectrum innate antiviral immunity in plants. [1]: /lookup/doi/10.1126/science.abb7360
领域	气候变化 ; 资源环境
URL	查看原文
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/298103
专题	气候变化资源环境科学
推荐引用方式 GB/T 7714	Haijun Wu,Xiaoya Qu,Zhicheng Dong,et al. WUSCHEL triggers innate antiviral immunity in plant stem cells[J]. Science,2020.
APA	Haijun Wu.,Xiaoya Qu.,Zhicheng Dong.,Linjie Luo.,Chen Shao.,...&Zhong Zhao.(2020).WUSCHEL triggers innate antiviral immunity in plant stem cells.Science.
MLA	Haijun Wu,et al."WUSCHEL triggers innate antiviral immunity in plant stem cells".Science (2020).