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DOI | 10.1007/s10584-016-1866-z |
A neural circuit architecture for angular integration in Drosophila | |
Green, Jonathan; Adachi, Atsuko; Shah, Kunal K.; Hirokawa, Jonathan D.; Magani, Pablo S.; Maimon, Gaby | |
2017-06-01 | |
发表期刊 | NATURE
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ISSN | 0028-0836 |
EISSN | 1476-4687 |
出版年 | 2017 |
卷号 | 546期号:7656页码:101-+ |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文摘要 | Many animals keep track of their angular heading over time while navigating through their environment. However, a neural-circuit architecture for computing heading has not been experimentally defined in any species. Here we describe a set of clockwise-and anticlockwise-shifting neurons in the Drosophila central complex whose wiring and physiology provide a means to rotate an angular heading estimate based on the fly's angular velocity. We show that each class of shifting neurons exists in two subtypes, with spatiotemporal activity profiles that suggest different roles for each subtype at the start and end of tethered-walking turns. Shifting neurons are required for the heading system to properly track the fly's heading in the dark, and stimulation of these neurons induces predictable shifts in the heading signal. The central features of this biological circuit are analogous to those of computational models proposed for head-direction cells in rodents and may shed light on how neural systems, in general, perform integration. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000402372800036 |
WOS关键词 | HEAD-DIRECTION CELLS ; FREELY MOVING RATS ; PATH-INTEGRATION ; PROTOCEREBRAL BRIDGE ; REPRESENTATION ; ORIENTATION ; POSTSUBICULUM ; DYNAMICS ; VELOCITY ; POSITION |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/29899 |
专题 | 气候变化 |
作者单位 | Rockefeller Univ, Lab Integrat Brain Funct, New York, NY 10065 USA |
推荐引用方式 GB/T 7714 | Green, Jonathan,Adachi, Atsuko,Shah, Kunal K.,et al. A neural circuit architecture for angular integration in Drosophila[J]. NATURE,2017,546(7656):101-+. |
APA | Green, Jonathan,Adachi, Atsuko,Shah, Kunal K.,Hirokawa, Jonathan D.,Magani, Pablo S.,&Maimon, Gaby.(2017).A neural circuit architecture for angular integration in Drosophila.NATURE,546(7656),101-+. |
MLA | Green, Jonathan,et al."A neural circuit architecture for angular integration in Drosophila".NATURE 546.7656(2017):101-+. |
条目包含的文件 | 条目无相关文件。 |
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