Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex

doi:10.1126/science.abd7435

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DOI	10.1126/science.abd7435
	Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex
	Xing Chen; Feng Wang; Eduardo Fernandez; Pieter R. Roelfsema
	2020-12-04
发表期刊	Science
出版年	2020
英文摘要	Electrical stimulation of the visual cortex has long been proposed as an approach to restoring vision in blind people. Previous studies positioned electrodes on the surface of the brain and thus required delivery of relatively high currents. However, this approach limits the number of electrodes that can be safely stimulated simultaneously, and such surface electrodes activate several millimeters of cortex, which results in a low spatial resolution. Chen et al. demonstrated that the simultaneous stimulation of multiple intracortical electrodes in the monkey primary visual cortex gives rise to the perception of shape and successive stimulation to the perception of motion (see the Perspective by Beauchamp and Yoshor). This major improvement provides proof of concept for the use of electrical microstimulation to create a form of artificial vision in the blind. Science , this issue p. [1191][1]; see also p. [1165][2] Blindness affects 40 million people across the world. A neuroprosthesis could one day restore functional vision in the blind. We implanted a 1024-channel prosthesis in areas V1 and V4 of the visual cortex of monkeys and used electrical stimulation to elicit percepts of dots of light (called phosphenes) on hundreds of electrodes, the locations of which matched the receptive fields of the stimulated neurons. Activity in area V4 predicted phosphene percepts that were elicited in V1. We simultaneously stimulated multiple electrodes to impose visible patterns composed of a number of phosphenes. The monkeys immediately recognized them as simple shapes, motions, or letters. These results demonstrate the potential of electrical stimulation to restore functional, life-enhancing vision in the blind. [1]: /lookup/doi/10.1126/science.abd7435 [2]: /lookup/doi/10.1126/science.abf1925
领域	气候变化 ; 资源环境
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文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/305833
专题	气候变化资源环境科学
推荐引用方式 GB/T 7714	Xing Chen,Feng Wang,Eduardo Fernandez,et al. Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex[J]. Science,2020.
APA	Xing Chen,Feng Wang,Eduardo Fernandez,&Pieter R. Roelfsema.(2020).Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex.Science.
MLA	Xing Chen,et al."Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex".Science (2020).