GSTDTAP  > 资源环境科学
Health experts give green light to Janssen COVID jab, allay clotting concerns
admin
2021-03-17
发布年2021
语种英语
国家国际
领域资源环境
正文(英文)

In a virtual press conference from Geneva, SAGE hailed the one-dose Janssen shot – produced by a Johnson & Johnson subsidiary - as a safe and lifesaving addition to the three other vaccines it has already approved for use: Pfizer, Moderna and AstraZeneca.

The expert panel also noted that clotting episodes - also known as hypercoagulable events - were a symptom of COVID-19, amid the suspension of the AstraZeneca/Oxford vaccine by several European countries, pending scientific review.

‘These are lifesaving products’

“The world is in a place where there is insufficient supply to meet the requirements of people who need to be vaccinated; clearly, any of these vaccines are lifesaving products”, said Dr. Kate O’Brien, Director, Department of Immunization, Vaccines and Biologicals at the World Health Organization (WHO).

She insisted that the vaccines “need to be used as quickly as we can get them deployed. People can have confidence in their safety and efficacy and in the quality of the manufacture of the products.”

During trials for the Janssen vaccine involving nearly 44,000 people, 10 of the 22,000 people who received the blank dose developed a blood clot – or thrombo-embolic events - while 14 of the remaining 22,000 who were inoculated, developed a clot.

“This is about the same”, for both groups said Dr Annelies Wilder-Smith, SAGE Technical Advisor. “There’s a slight imbalance, but it’s still not statistically significant,”

No evidence clots related to vaccines

“As for the vaccine itself, we have not seen it in a trial, there’s no reason to think and no biological causability as far we understand now, that the vaccine could cause thrombo-embolic events itself. However, we have to be open for new events, and we have to take it seriously.”

Dr Wilder-Smith explained that those recruited for vaccine testing were intentionally chosen because they were people who were “at high risk” of developing blood clots.

“COVID really pre-disposes patients to a hypercoagulable state where indeed many of the deaths that we see in the severe cases are due to thrombo-embolic events”, Dr Wilder-Smith said, ahead of an expected announcement by the European Medicines Agency (EMA) on the issue on Thursday.

In a statement released on Wednesday specifically adressing the AstraZenica suspension by some European nations, the agency said it was "good practice" to investigate the possible linkages, that the benefits of the vaccine "outweigh its risks" and WHO "recommends that vaccinations continue."

Infections heading up

The development comes amid a rise in new cases of coronavirus infection worldwide, increasing by 10 per cent in the past week, to more than three million new reported cases.

WHO reported on Wednesday that after peaking in early January 2021 - when there were just under five million cases a week - new cases then declined to around 2.5 million in the week commencing 15 February 2021.

But the past three weeks have seen cases increasing again.

This week, the Americas and Europe continue to account for more than 80 per cent of new cases and new deaths, with rises in new cases in all regions - apart from Africa, where they remained the same as last week.

As of 17 March 2021, there have been 120,164,106 confirmed cases of COVID-19, including 2,660,422 deaths, reported to WHO.

More than 363,000,000 vaccine doses have been administered globally.

URL查看原文
来源平台UN Sustainable Development Goals
文献类型新闻
条目标识符http://119.78.100.173/C666/handle/2XK7JSWQ/319707
专题资源环境科学
推荐引用方式
GB/T 7714
admin. Health experts give green light to Janssen COVID jab, allay clotting concerns. 2021.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[admin]的文章
百度学术
百度学术中相似的文章
[admin]的文章
必应学术
必应学术中相似的文章
[admin]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。