Type 1 diabetes glycemic management: Insulin therapy, glucose monitoring, and automation

doi:10.1126/science.abg4502

GSTDTAP > 气候变化

DOI	10.1126/science.abg4502
	Type 1 diabetes glycemic management: Insulin therapy, glucose monitoring, and automation
	Bruce A. Perkins; Jennifer L. Sherr; Chantal Mathieu
	2021-07-30
发表期刊	Science
出版年	2021
英文摘要	Despite innovations in insulin therapy since its discovery, most patients living with type 1 diabetes do not achieve sufficient glycemic control to prevent complications, and they experience hypoglycemia, weight gain, and major self-care burden. Promising pharmacological advances in insulin therapy include the refinement of extremely rapid insulin analogs, alternate insulin-delivery routes, liver-selective insulins, add-on drugs that enhance insulin effect, and glucose-responsive insulin molecules. The greatest future impact will come from combining these pharmacological solutions with existing automated insulin delivery methods that integrate insulin pumps and glucose sensors. These systems will use algorithms enhanced by machine learning, supplemented by technologies that include activity monitors and sensors for other key metabolites such as ketones. The future challenges facing clinicians and researchers will be those of access and broad clinical implementation.
领域	气候变化 ; 资源环境
URL	查看原文
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/335510
专题	气候变化资源环境科学
推荐引用方式 GB/T 7714	Bruce A. Perkins,Jennifer L. Sherr,Chantal Mathieu. Type 1 diabetes glycemic management: Insulin therapy, glucose monitoring, and automation[J]. Science,2021.
APA	Bruce A. Perkins,Jennifer L. Sherr,&Chantal Mathieu.(2021).Type 1 diabetes glycemic management: Insulin therapy, glucose monitoring, and automation.Science.
MLA	Bruce A. Perkins,et al."Type 1 diabetes glycemic management: Insulin therapy, glucose monitoring, and automation".Science (2021).