Horizontally transmitted parasitoid killing factor shapes insect defense to parasitoids

doi:10.1126/science.abb6396

GSTDTAP > 气候变化

DOI	10.1126/science.abb6396
	Horizontally transmitted parasitoid killing factor shapes insect defense to parasitoids
	Laila Gasmi; Edyta Sieminska; Shohei Okuno; Rie Ohta; Cathy Coutu; Mohammad Vatanparast; Stephanie Harris; Doug Baldwin; Dwayne D. Hegedus; David A. Theilmann; Aki Kida; Mio Kawabata; Shiori Sagawa; Jun Takatsuka; Ken Tateishi; Kazuyo Watanabe; Maki N. Inoue; Yasuhisa Kunimi; Yonggyun Kim; Martin A. Erlandson; Salvador Herrero; Madoka Nakai
	2021-07-30
发表期刊	Science
出版年	2021
英文摘要	Parasitoid wasps have developed myriad systems to overcome the defense mechanisms of their hosts as they lay their eggs in the bodies and eggs of targeted species. Gasmi et al. report how the host can fight back when infected by a virus that expresses a protein conferring resistance to the parasitoid. When members of the butterfly and moth family are targeted by wasps, a protein family has evolved that is horizontally carried by viruses—and sometimes is incorporated into the host genome—and impairs the ability of parasitoid offspring to fully develop and emerge. Characterizing the ability of this protein to protect hosts against specific parasites, the authors document an ongoing host-parasite evolutionary arms race. Science , abb6396, this issue p. [535][1] Interkingdom competition occurs between hymenopteran parasitoids and insect viruses sharing the same insect hosts. It has been assumed that parasitoid larvae die with the death of the infected host or as result of competition for host resources. Here we describe a gene family, parasitoid killing factor ( pkf ), that encodes proteins toxic to parasitoids of the Microgastrinae group and determines parasitism success. Pkfs are found in several entomopathogenic DNA virus families and in some lepidopteran genomes. We provide evidence of equivalent and specific toxicity against endoparasites for PKFs found in entomopoxvirus, ascovirus, baculovirus, and Lepidoptera through a mechanism that elicits apoptosis in the cells of susceptible parasitoids. This highlights the evolutionary arms race between parasitoids, viruses, and their insect hosts. [1]: /lookup/doi/10.1126/science.abb6396
领域	气候变化 ; 资源环境
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文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/335537
专题	气候变化资源环境科学
推荐引用方式 GB/T 7714	Laila Gasmi,Edyta Sieminska,Shohei Okuno,et al. Horizontally transmitted parasitoid killing factor shapes insect defense to parasitoids[J]. Science,2021.
APA	Laila Gasmi.,Edyta Sieminska.,Shohei Okuno.,Rie Ohta.,Cathy Coutu.,...&Madoka Nakai.(2021).Horizontally transmitted parasitoid killing factor shapes insect defense to parasitoids.Science.
MLA	Laila Gasmi,et al."Horizontally transmitted parasitoid killing factor shapes insect defense to parasitoids".Science (2021).