Population-scale sequencing and the future of genomic medicine: Learning from past and present efforts

doi:10.7249/RR1520

GSTDTAP > 资源环境科学

DOI	10.7249/RR1520
报告编号	RR-1520-RE
	Population-scale sequencing and the future of genomic medicine: Learning from past and present efforts
	Talitha Dubow; Sonja Marjanovic
	2016
出版年	2016
页数	78
语种	英语
国家	美国
出版者	RAND Corporation
领域	资源环境
英文摘要	Genomic medicine, as a field, has the potential to change the way we prevent, manage and treat disease. Although the routine implementation of genomic medicine in clinical care is yet to be realised, diverse national and international initiatives are narrowing the gap between prospect and practice. This paper provides a reflection on the variety of population-scale genome-sequencing efforts that have emerged over the past two decades and examines their social implications. We analyse the progress these initiatives have made, both in terms of their scientific, technological and biomedical contributions, and in terms of their influence on the institutions that govern science and innovation more widely. Based on our analysis, we identify five areas of action for a future research and policy agenda to consider. These span issues related to: i) the scale-up of existing efforts and the need for more cross-sector collaboration for clinically-relevant sense-making; ii) the implications of genomics in clinical settings; iii) changes in industry R&D models that are likely to accompany further advances in genomic medicine; iv) consolidating learning about appropriate research ethics frameworks and clarifying the legal arrangements necessary for genomic medicine; and v) wider evaluation and learning from past and current efforts.
英文关键词	Bioethics Populations Genomic Medicine Health Care Technology
URL	查看原文
来源平台	Rand Corporation
引用统计
文献类型	科技报告
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/4452
专题	资源环境科学
推荐引用方式 GB/T 7714	Talitha Dubow,Sonja Marjanovic. Population-scale sequencing and the future of genomic medicine: Learning from past and present efforts:RAND Corporation,2016.