Final Technical Report for Award # ER64999

doi:10.2172/1159247

GSTDTAP > 地球科学

DOI	10.2172/1159247
报告编号	DOE-UIUC-SC5348
来源ID	OSTI ID: 1159247
	Final Technical Report for Award # ER64999
	Metcalf, William W.
	2014-10-08
出版年	2014
语种	英语
国家	美国
领域	地球科学
英文摘要	This report provides a summary of activities for Award # ER64999, a Genomes to Life Project funded by the Office of Science, Basic Energy Research. The project was entitled "Methanogenic archaea and the global carbon cycle: a systems biology approach to the study of Methanosarcina species". The long-term goal of this multi-investigator project was the creation of integrated, multiscale models that accurately and quantitatively predict the role of Methanosarcina species in the global carbon cycle under dynamic environmental conditions. To achieve these goals we pursed four specific aims: (1) genome sequencing of numerous members of the Order Methanosarcinales, (2) identification of genomic sources of phenotypic variation through in silico comparative genomics, (3) elucidation of the transcriptional networks of two Methanosarcina species, and (4) development of comprehensive metabolic network models for characterized strains to address the question of how metabolic models scale with genetic distance.
英文关键词	methane methanogenic archaea systems biology genomics transcriptomics metabolic modelling
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来源平台	US Department of Energy (DOE)
引用统计
文献类型	科技报告
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/6548
专题	地球科学
推荐引用方式 GB/T 7714	Metcalf, William W.. Final Technical Report for Award # ER64999,2014.