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A systematic global stocktake of evidence on human adaptation to climate change 科技报告
来源:Climate Analytics. 出版年: 2021
作者:  Lea Berrang-Ford;  A. R. Siders;  Alexandra Lesnikowski;  Alexandra Paige Fischer;  Max W. Callaghan;  Neal R. Haddaway;  Katharine J. Mach;  Malcolm Araos;  Mohammad Aminur Rahman Shah;  Mia Wannewitz;  Deepal Doshi;  Timo Leiter;  Custodio Matavel;  Justice Issah Musah-Surugu;  Gabrielle Wong-Parodi;  Philip Antwi-Agyei;  Idowu Ajibade;  Neha Chauhan;  William Kakenmaster;  Caitlin Grady;  Vasiliki I. Chalastani;  Kripa Jagannathan;  Eranga K. Galappaththi;  Asha Sitati;  Giulia Scarpa;  Edmond Totin;  Katy Davis;  Nikita Charles Hamilton;  Christine J. Kirchhoff;  Praveen Kumar;  Brian Pentz;  Nicholas P. Simpson;  Emily Theokritoff;  Delphine Deryng;  Diana Reckien;  Carol Zavaleta-Cortijo;  Nicola Ulibarri;  Alcade C. Segnon;  Vhalinavho Khavhagali;  Yuanyuan Shang;  Luckson Zvobgo;  Zinta Zommers;  Jiren Xu;  Portia Adade Williams;  Ivan Villaverde Canosa;  Nicole van Maanen;  Bianca van Bavel;  Maarten van Aalst;  Lynée L. Turek-Hankins;  Hasti Trivedi;  Christopher H. Trisos;  Adelle Thomas;  Shinny Thakur;  Sienna Templeman;  Lindsay C. Stringer;  Garry Sotnik;  Kathryn Dana Sjostrom;  Chandni Singh;  Mariella Z. Siña;  Roopam Shukla;  Jordi Sardans;  Eunice A. Salubi;  Lolita Shaila Safaee Chalkasra;  Raquel Ruiz-Díaz;  Carys Richards;  Pratik Pokharel;  Jan Petzold;  Josep Penuelas;  Julia Pelaez Avila;  Julia B. Pazmino Murillo;  Souha Ouni;  Jennifer Niemann;  Miriam Nielsen;  Mark New;  Patricia Nayna Schwerdtle;  Gabriela Nagle Alverio;  Cristina A. Mullin;  Joshua Mullenite;  Anuszka Mosurska;  Mike D. Morecroft;  Jan C. Minx;  Gina Maskell;  Abraham Marshall Nunbogu;  Alexandre K. Magnan;  Shuaib Lwasa;  Megan Lukas-Sithole;  Tabea Lissner;  Oliver Lilford;  Steven F. Koller;  Matthew Jurjonas;  Elphin Tom Joe;  Lam T. M. Huynh;  Avery Hill;  Rebecca R. Hernandez;  Greeshma Hegde;  Tom Hawxwell;  Sherilee Harper;  Alexandra Harden;  Marjolijn Haasnoot;  Elisabeth A. Gilmore;  Leah Gichuki;  Alyssa Gatt;  Matthias Garschagen;  James D. Ford;  Andrew Forbes;  Aidan D. Farrell;  Carolyn A. F. Enquist;  Susan Elliott;  Emily Duncan;  Erin Coughlan de Perez;  Shaugn Coggins;  Tara Chen;  Donovan Campbell;  Katherine E. Browne;  Kathryn J. Bowen;  Robbert Biesbroek;  Indra D. Bhatt;  Rachel Bezner Kerr;  Stephanie L. Barr;  Emily Baker;  Stephanie E. Austin;  Ingrid Arotoma-Rojas;  Christa Anderson;  Warda Ajaz;  Tanvi Agrawal;  Thelma Zulfawu Abu
收藏  |  浏览/下载:20/0  |  提交时间:2022/01/29
High Temporal Resolution Satellite Observations of Fire Radiative Power Reveal Link Between Fire Behavior and Aerosol and Gas Emissions 期刊论文
Geophysical Research Letters, 2020
作者:  Elizabeth B. Wiggins;  Amber J. Soja;  Emily Gargulinski;  Hannah S. Halliday;  R. Bradley Pierce;  Christopher C. Schmidt;  John B. Nowak;  Joshua P. DiGangi;  Glenn S. Diskin;  Joseph M. Katich;  Anne E. Perring;  Joshua P. Schwarz;  Bruce E. Anderson;  Gao Chen;  Ewan C. Crosbie;  Carolyn Jordan;  Claire E. Robinson;  Kevin J. Sanchez;  Taylor J. Shingler;  Michael Shook;  Kenneth L. Thornhill;  Edward L. Winstead;  Luke D. Ziemba;  Richard H. Moore
收藏  |  浏览/下载:10/0  |  提交时间:2020/11/30
Wrong-way migrations of benthic species driven by ocean warming and larval transport 期刊论文
Nature, 2020
作者:  Heidi L. Fuchs;  Robert J. Chant;  Elias J. Hunter;  Enrique N. Curchitser;  Gregory P. Gerbi;  Emily Y. Chen
收藏  |  浏览/下载:6/0  |  提交时间:2020/09/14
Electrical manipulation of a topological antiferromagnetic state 期刊论文
NATURE, 2020, 580 (7805) : 608-+
作者:  Chabon, Jacob J.;  Hamilton, Emily G.;  Kurtz, David M.;  Esfahani, Mohammad S.;  Moding, Everett J.;  Stehr, Henning;  Schroers-Martin, Joseph;  Nabet, Barzin Y.;  Chen, Binbin;  Chaudhuri, Aadel A.;  Liu, Chih Long;  Hui, Angela B.;  Jin, Michael C.;  Azad, Tej D.;  Almanza, Diego;  Jeon, Young-Jun;  Nesselbush, Monica C.;  Keh, Lyron Co Ting;  Bonilla, Rene F.;  Yoo, Christopher H.;  Ko, Ryan B.;  Chen, Emily L.;  Merriott, David J.;  Massion, Pierre P.;  Mansfield, Aaron S.;  Jen, Jin;  Ren, Hong Z.;  Lin, Steven H.;  Costantino, Christina L.;  Burr, Risa;  Tibshirani, Robert;  Gambhir, Sanjiv S.;  Berry, Gerald J.;  Jensen, Kristin C.;  West, Robert B.;  Neal, Joel W.;  Wakelee, Heather A.;  Loo, Billy W., Jr.;  Kunder, Christian A.;  Leung, Ann N.;  Lui, Natalie S.;  Berry, Mark F.;  Shrager, Joseph B.;  Nair, Viswam S.;  Haber, Daniel A.;  Sequist, Lecia V.;  Alizadeh, Ash A.;  Diehn, Maximilian
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/03

Room-temperature electrical switching of a topological antiferromagnetic state in polycrystalline Mn3Sn thin films is demonstrated using the same protocol as that used for conventional ferromagnetic metals.


Electrical manipulation of phenomena generated by nontrivial band topology is essential for the development of next-generation technology using topological protection. A Weyl semimetal is a three-dimensional gapless system that hosts Weyl fermions as low-energy quasiparticles(1-4). It has various exotic properties, such as a large anomalous Hall effect (AHE) and chiral anomaly, which are robust owing to the topologically protected Weyl nodes(1-16). To manipulate such phenomena, a magnetic version of Weyl semimetals would be useful for controlling the locations of Weyl nodes in the Brillouin zone. Moreover, electrical manipulation of antiferromagnetic Weyl metals would facilitate the use of antiferromagnetic spintronics to realize high-density devices with ultrafast operation(17,18). However, electrical control of a Weyl metal has not yet been reported. Here we demonstrate the electrical switching of a topological antiferromagnetic state and its detection by the AHE at room temperature in a polycrystalline thin film(19) of the antiferromagnetic Weyl metal Mn3Sn9,10,12,20, which exhibits zero-field AHE. Using bilayer devices composed of Mn3Sn and nonmagnetic metals, we find that an electrical current density of about 10(10) to 10(11) amperes per square metre induces magnetic switching in the nonmagnetic metals, with a large change in Hall voltage. In addition, the current polarity along the bias field and the sign of the spin Hall angle of the nonmagnetic metals-positive for Pt (ref. (21)), close to 0 for Cu and negative for W (ref. (22))-determines the sign of the Hall voltage. Notably, the electrical switching in the antiferromagnet is achieved with the same protocol as that used for ferromagnetic metals(23,24). Our results may lead to further scientific and technological advances in topological magnetism and antiferromagnetic spintronics.


  
Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome 期刊论文
NATURE, 2020
作者:  Coll, Anthony P.;  Chen, Michael;  Taskar, Pranali;  Rimmington, Debra;  Patel, Satish;  Tadross, John A.;  Cimino, Irene;  Yang, Ming;  Welsh, Paul;  Virtue, Samuel;  Goldspink, Deborah A.;  Miedzybrodzka, Emily L.;  Konopka, Adam R.;  Esponda, Raul Ruiz;  Huang, Jeffrey T. -J.;  Tung, Y. C. Loraine;  Rodriguez-Cuenca, Sergio
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/03

The cryo-electron microscopy structure of the 16-subunit yeast SWI/SNF complex RSC in complex with a nucleosome substrate provides insights into the chromatin-remodelling function of this family of protein complexes.


Chromatin-remodelling complexes of the SWI/SNF family function in the formation of nucleosome-depleted, transcriptionally active promoter regions (NDRs)(1,2). In the yeast Saccharomyces cerevisiae, the essential SWI/SNF complex RSC3 contains 16 subunits, including the ATP-dependent DNA translocase Sth1(4,5). RSC removes nucleosomes from promoter regions(6,7) and positions the specialized +1 and -1 nucleosomes that flank NDRs(8,9). Here we present the cryo-electron microscopy structure of RSC in complex with a nucleosome substrate. The structure reveals that RSC forms five protein modules and suggests key features of the remodelling mechanism. The body module serves as a scaffold for the four flexible modules that we call DNA-interacting, ATPase, arm and actin-related protein (ARP) modules. The DNA-interacting module binds extra-nucleosomal DNA and is involved in the recognition of promoter DNA elements(8,10,11) that influence RSC functionality(12). The ATPase and arm modules sandwich the nucleosome disc with the Snf2 ATP-coupling (SnAC) domain and the finger helix, respectively. The translocase motor of the ATPase module engages with the edge of the nucleosome at superhelical location +2. The mobile ARP module may modulate translocase-nucleosome interactions to regulate RSC activity(5). The RSC-nucleosome structure provides a basis for understanding NDR formation and the structure and function of human SWI/SNF complexes that are frequently mutated in cancer(13).


  
A proof of concept for structure-based vaccine design targeting RSV in humans 期刊论文
SCIENCE, 2019, 365 (6452) : 505-+
作者:  Crank, Michelle C.;  Ruckwardt, Tracy J.;  Chen, Man;  Morabito, Kaitlyn M.;  Phung, Emily;  Costner, Pamela J.;  Holman, LaSonji A.;  Hickman, Somia P.;  Berkowitz, Nina M.;  Gordon, Ingelise J.;  Yamshchikov, Galina V.;  Gaudinski, Martin R.;  Kumar, Azad;  Chang, Lauren A.;  Moin, Syed M.;  Hill, Juliane P.;  DiPiazza, Anthony T.;  Schwartz, Richard M.;  Kueltzo, Lisa;  Cooper, Jonathan W.;  Chen, Peifeng;  Stein, Judith A.;  Carlton, Kevin;  Gall, Jason G.;  Nason, Martha C.;  Kwong, Peter D.;  Chen, Grace L.;  Mascola, John R.;  McLellan, Jason S.;  Ledgerwood, Julie E.;  Graham, Barney S.
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27