GSTDTAP

浏览/检索结果: 共27条,第1-10条 帮助

已选(0)清除 条数/页:   排序方式:
Noninvasive Dual-Modality Photoacoustic-Ultrasonic Imaging to Detect Mammalian Embryo Abnormalities after Prenatal Exposure to Methylmercury Chloride (MMC): A Mouse Study 期刊论文
Environmental Health Perspectives, 2022
作者:  Qi Qiu;  Yali Huang;  Bei Zhang;  Doudou Huang;  Xin Chen;  Zhongxiong Fan;  Jinpei Lin;  Wensheng Yang;  Kai Wang;  Ning Qu;  Juan Li;  Zhihong Li;  Jingyu Huang;  Shenrui Li;  Jiaxing Zhang;  Gang Liu;  Gang Rui;  Xiaoyuan Chen;  Qingliang Zhao
收藏  |  浏览/下载:63/0  |  提交时间:2022/02/16
Liquid medium annealing for fabricating durable perovskite solar cells with improved reproducibility 期刊论文
Science, 2021
作者:  Nengxu Li;  Xiuxiu Niu;  Liang Li;  Hao Wang;  Zijian Huang;  Yu Zhang;  Yihua Chen;  Xiao Zhang;  Cheng Zhu;  Huachao Zai;  Yang Bai;  Sai Ma;  Huifen Liu;  Xixia Liu;  Zhenyu Guo;  Guilin Liu;  Rundong Fan;  Hong Chen;  Jianpu Wang;  Yingzhuo Lun;  Xueyun Wang;  Jiawang Hong;  Haipeng Xie;  Devon S. Jakob;  Xiaoji G. Xu;  Qi Chen;  Huanping Zhou
收藏  |  浏览/下载:74/0  |  提交时间:2021/08/10
Peta–electron volt gamma-ray emission from the Crab Nebula 期刊论文
Science, 2021
作者:  The LHAASO Collaboration*†;  Zhen Cao;  F. Aharonian;  Q. An;  Axikegu;  L. X. Bai;  Y. X. Bai;  Y. W. Bao;  D. Bastieri;  X. J. Bi;  Y. J. Bi;  H. Cai;  J. T. Cai;  Zhe Cao;  J. Chang;  J. F. Chang;  B. M. Chen;  E. S. Chen;  J. Chen;  Liang Chen;  Liang Chen;  Long Chen;  M. J. Chen;  M. L. Chen;  Q. H. Chen;  S. H. Chen;  S. Z. Chen;  T. L. Chen;  X. L. Chen;  Y. Chen;  N. Cheng;  Y. D. Cheng;  S. W. Cui;  X. H. Cui;  Y. D. Cui;  B. D’Ettorre Piazzoli;  B. Z. Dai;  H. L. Dai;  Z. G. Dai;  Danzengluobu;  D. della Volpe;  X. J. Dong;  K. K. Duan;  J. H. Fan;  Y. Z. Fan;  Z. X. Fan;  J. Fang;  K. Fang;  C. F. Feng;  L. Feng;  S. H. Feng;  Y. L. Feng;  B. Gao;  C. D. Gao;  L. Q. Gao;  Q. Gao;  W. Gao;  M. M. Ge;  L. S. Geng;  G. H. Gong;  Q. B. Gou;  M. H. Gu;  F. L. Guo;  J. G. Guo;  X. L. Guo;  Y. Q. Guo;  Y. Y. Guo;  Y. A. Han;  H. H. He;  H. N. He;  J. C. He;  S. L. He;  X. B. He;  Y. He;  M. Heller;  Y. K. Hor;  C. Hou;  X. Hou;  H. B. Hu;  S. Hu;  S. C. Hu;  X. J. Hu;  D. H. Huang;  Q. L. Huang;  W. H. Huang;  X. T. Huang;  X. Y. Huang;  Z. C. Huang;  F. Ji;  X. L. Ji;  H. Y. Jia;  K. Jiang;  Z. J. Jiang;  C. Jin;  T. Ke;  D. Kuleshov;  K. Levochkin;  B. B. Li;  Cheng Li;  Cong Li;  F. Li;  H. B. Li;  H. C. Li;  H. Y. Li;  Jian Li;  Jie Li;  K. Li;  W. L. Li;  X. R. Li;  Xin Li;  Xin Li;  Y. Li;  Y. Z. Li;  Zhe Li;  Zhuo Li;  E. W. Liang;  Y. F. Liang;  S. J. Lin;  B. Liu;  C. Liu;  D. Liu;  H. Liu;  H. D. Liu;  J. Liu;  J. L. Liu;  J. S. Liu;  J. Y. Liu;  M. Y. Liu;  R. Y. Liu;  S. M. Liu;  W. Liu;  Y. Liu;  Y. N. Liu;  Z. X. Liu;  W. J. Long;  R. Lu;  H. K. Lv;  B. Q. Ma;  L. L. Ma;  X. H. Ma;  J. R. Mao;  A. Masood;  Z. Min;  W. Mitthumsiri;  T. Montaruli;  Y. C. Nan;  B. Y. Pang;  P. Pattarakijwanich;  Z. Y. Pei;  M. Y. Qi;  Y. Q. Qi;  B. Q. Qiao;  J. J. Qin;  D. Ruffolo;  V. Rulev;  A. Saiz;  L. Shao;  O. Shchegolev;  X. D. Sheng;  J. Y. Shi;  H. C. Song;  Yu. V. Stenkin;  V. Stepanov;  Y. Su;  Q. N. Sun;  X. N. Sun;  Z. B. Sun;  P. H. T. Tam;  Z. B. Tang;  W. W. Tian;  B. D. Wang;  C. Wang;  H. Wang;  H. G. Wang;  J. C. Wang;  J. S. Wang;  L. P. Wang;  L. Y. Wang;  R. N. Wang;  Wei Wang;  Wei Wang;  X. G. Wang;  X. J. Wang;  X. Y. Wang;  Y. Wang;  Y. D. Wang;  Y. J. Wang;  Y. P. Wang;  Z. H. Wang;  Z. X. Wang;  Zhen Wang;  Zheng Wang;  D. M. Wei;  J. J. Wei;  Y. J. Wei;  T. Wen;  C. Y. Wu;  H. R. Wu;  S. Wu;  W. X. Wu;  X. F. Wu;  S. Q. Xi;  J. Xia;  J. J. Xia;  G. M. Xiang;  D. X. Xiao;  G. Xiao;  H. B. Xiao;  G. G. Xin;  Y. L. Xin;  Y. Xing;  D. L. Xu;  R. X. Xu;  L. Xue;  D. H. Yan;  J. Z. Yan;  C. W. Yang;  F. F. Yang;  J. Y. Yang;  L. L. Yang;  M. J. Yang;  R. Z. Yang;  S. B. Yang;  Y. H. Yao;  Z. G. Yao;  Y. M. Ye;  L. Q. Yin;  N. Yin;  X. H. You;  Z. Y. You;  Y. H. Yu;  Q. Yuan;  H. D. Zeng;  T. X. Zeng;  W. Zeng;  Z. K. Zeng;  M. Zha;  X. X. Zhai;  B. B. Zhang;  H. M. Zhang;  H. Y. Zhang;  J. L. Zhang;  J. W. Zhang;  L. X. Zhang;  Li Zhang;  Lu Zhang;  P. F. Zhang;  P. P. Zhang;  R. Zhang;  S. R. Zhang;  S. S. Zhang;  X. Zhang;  X. P. Zhang;  Y. F. Zhang;  Y. L. Zhang;  Yi Zhang;  Yong Zhang;  B. Zhao;  J. Zhao;  L. Zhao;  L. Z. Zhao;  S. P. Zhao;  F. Zheng;  Y. Zheng;  B. Zhou;  H. Zhou;  J. N. Zhou;  P. Zhou;  R. Zhou;  X. X. Zhou;  C. G. Zhu;  F. R. Zhu;  H. Zhu;  K. J. Zhu;  X. Zuo
收藏  |  浏览/下载:101/0  |  提交时间:2021/07/27
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy 期刊论文
Science, 2020
作者:  Hongjing Gu;  Qi Chen;  Guan Yang;  Lei He;  Hang Fan;  Yong-Qiang Deng;  Yanxiao Wang;  Yue Teng;  Zhongpeng Zhao;  Yujun Cui;  Yuchang Li;  Xiao-Feng Li;  Jiangfan Li;  Na-Na Zhang;  Xiaolan Yang;  Shaolong Chen;  Yan Guo;  Guangyu Zhao;  Xiliang Wang;  De-Yan Luo;  Hui Wang;  Xiao Yang;  Yan Li;  Gencheng Han;  Yuxian He;  Xiaojun Zhou;  Shusheng Geng;  Xiaoli Sheng;  Shibo Jiang;  Shihui Sun;  Cheng-Feng Qin;  Yusen Zhou
收藏  |  浏览/下载:41/0  |  提交时间:2020/09/30
Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody 期刊论文
Science, 2020
作者:  Zhe Lv;  Yong-Qiang Deng;  Qing Ye;  Lei Cao;  Chun-Yun Sun;  Changfa Fan;  Weijin Huang;  Shihui Sun;  Yao Sun;  Ling Zhu;  Qi Chen;  Nan Wang;  Jianhui Nie;  Zhen Cui;  Dandan Zhu;  Neil Shaw;  Xiao-Feng Li;  Qianqian Li;  Liangzhi Xie;  Youchun Wang;  Zihe Rao;  Cheng-Feng Qin;  Xiangxi Wang
收藏  |  浏览/下载:57/0  |  提交时间:2020/09/22
Characterization of submicron particles by time-of-flight aerosol chemical speciation monitor (ToF-ACSM) during wintertime: aerosol composition, sources, and chemical processes in Guangzhou, China 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (12) : 7595-7615
作者:  Guo, Junchen;  Zhou, Shengzhen;  Cai, Mingfu;  Zhao, Jun;  Song, Wei;  Zhao, Weixiong;  Hu, Weiwei;  Sun, Yele;  He, Yao;  Yang, Chengqiang;  Xu, Xuezhe;  Zhang, Zhisheng;  Cheng, Peng;  Fan, Qi;  Hang, Jian;  Fan, Shaojia;  Wang, Xinming;  Wang, Xuemei
收藏  |  浏览/下载:42/0  |  提交时间:2020/07/06
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 期刊论文
Science, 2020
作者:  Yan Wu;  Feiran Wang;  Chenguang Shen;  Weiyu Peng;  Delin Li;  Cheng Zhao;  Zhaohui Li;  Shihua Li;  Yuhai Bi;  Yang Yang;  Yuhuan Gong;  Haixia Xiao;  Zheng Fan;  Shuguang Tan;  Guizhen Wu;  Wenjie Tan;  Xuancheng Lu;  Changfa Fan;  Qihui Wang;  Yingxia Liu;  Chen Zhang;  Jianxun Qi;  George Fu Gao;  Feng Gao;  Lei Liu
收藏  |  浏览/下载:38/0  |  提交时间:2020/06/16
Accelerated discovery of CO2 electrocatalysts using active machine learning 期刊论文
NATURE, 2020, 581 (7807) : 178-+
作者:  Lan, Jun;  Ge, Jiwan;  Yu, Jinfang;  Shan, Sisi;  Zhou, Huan;  Fan, Shilong;  Zhang, Qi;  Shi, Xuanling;  Wang, Qisheng;  Zhang, Linqi;  Wang, Xinquan
收藏  |  浏览/下载:125/0  |  提交时间:2020/07/03

The rapid increase in global energy demand and the need to replace carbon dioxide (CO2)-emitting fossil fuels with renewable sources have driven interest in chemical storage of intermittent solar and wind energy(1,2). Particularly attractive is the electrochemical reduction of CO2 to chemical feedstocks, which uses both CO2 and renewable energy(3-8). Copper has been the predominant electrocatalyst for this reaction when aiming for more valuable multi-carbon products(9-16), and process improvements have been particularly notable when targeting ethylene. However, the energy efficiency and productivity (current density) achieved so far still fall below the values required to produce ethylene at cost-competitive prices. Here we describe Cu-Al electrocatalysts, identified using density functional theory calculations in combination with active machine learning, that efficiently reduce CO2 to ethylene with the highest Faradaic efficiency reported so far. This Faradaic efficiency of over 80 per cent (compared to about 66 per cent for pure Cu) is achieved at a current density of 400 milliamperes per square centimetre (at 1.5 volts versus a reversible hydrogen electrode) and a cathodic-side (half-cell) ethylene power conversion efficiency of 55 +/- 2 per cent at 150 milliamperes per square centimetre. We perform computational studies that suggest that the Cu-Al alloys provide multiple sites and surface orientations with near-optimal CO binding for both efficient and selective CO2 reduction(17). Furthermore, in situ X-ray absorption measurements reveal that Cu and Al enable a favourable Cu coordination environment that enhances C-C dimerization. These findings illustrate the value of computation and machine learning in guiding the experimental exploration of multi-metallic systems that go beyond the limitations of conventional single-metal electrocatalysts.


  
Depth‐dependent soil organic carbon dynamics of croplands across the Chengdu Plain of China from the 1980s to the 2010s 期刊论文
Global Change Biology, 2020
作者:  Qiquan Li;  Aiwen Li;  Tianfei Dai;  Zemeng Fan;  Youlin Luo;  Shan Li;  Dagang Yuan;  Bin Zhao;  Qi Tao;  Changquan Wang;  Bing Li;  Xuesong Gao;  Yiding Li;  Huanxiu Li;  John P. Wilson
收藏  |  浏览/下载:14/0  |  提交时间:2020/05/13
Structure and mechanism of human diacylglycerol O-acyltransferase 1 期刊论文
NATURE, 2020, 581 (7808) : 329-+
作者:  Wu, Fan;  Zhao, Su;  Yu, Bin;  Chen, Yan-Mei;  Wang, Wen;  Song, Zhi-Gang;  Hu, Yi;  Tao, Zhao-Wu;  Tian, Jun-Hua;  Pei, Yuan-Yuan;  Yuan, Ming-Li;  Zhang, Yu-Ling;  Dai, Fa-Hui;  Liu, Yi;  Wang, Qi-Min;  Zheng, Jiao-Jiao;  Xu, Lin;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载:51/0  |  提交时间:2020/07/03

The structure of human diacylglycerol O-acyltransferase 1, a membrane protein that synthesizes triacylglycerides, is solved with cryo-electron microscopy, providing insight into its function and mechanism of enzymatic activity.


Diacylglycerol O-acyltransferase 1 (DGAT1) synthesizes triacylglycerides and is required for dietary fat absorption and fat storage in humans(1). DGAT1 belongs to the membrane-bound O-acyltransferase (MBOAT) superfamily, members of which are found in all kingdoms of life and are involved in the acylation of lipids and proteins(2,3). How human DGAT1 and other mammalian members of the MBOAT family recognize their substrates and catalyse their reactions is unknown. The absence of three-dimensional structures also hampers rational targeting of DGAT1 for therapeutic purposes. Here we present the cryo-electron microscopy structure of human DGAT1 in complex with an oleoyl-CoA substrate. Each DGAT1 protomer has nine transmembrane helices, eight of which form a conserved structural fold that we name the MBOAT fold. The MBOAT fold in DGAT1 forms a hollow chamber in the membrane that encloses highly conserved catalytic residues. The chamber has separate entrances for each of the two substrates, fatty acyl-CoA and diacylglycerol. DGAT1 can exist as either a homodimer or a homotetramer and the two forms have similar enzymatic activity. The N terminus of DGAT1 interacts with the neighbouring protomer and these interactions are required for enzymatic activity.