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Diurnal cycle of cirrus cloud and its associated radiative effects at the SACOL site 期刊论文
Atmospheric Research, 2021
作者:  Meihua Wang, Jing Su, Nan Peng, Ying Xu, Jinming Ge
收藏  |  浏览/下载:31/0  |  提交时间:2021/10/22
Characteristics and causes of surface wind speed variations in Northwest China from 1979 to 2019 期刊论文
Atmospheric Research, 2021
作者:  Jing Ge, Dongpu Feng, Qinglong You, Weijiang Zhang, Yuqing Zhang
收藏  |  浏览/下载:27/0  |  提交时间:2021/02/22
A 1-year characterization of organic aerosol composition and sources using an extractive electrospray ionization time-of-flight mass spectrometer (EESI-TOF) 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (13) : 7875-7893
作者:  Qi, Lu;  Vogel, Alexander L.;  Esmaeilirad, Sepideh;  Cao, Liming;  Zheng, Jing;  Jaffrezo, Jean-Luc;  Fermo, Paola;  Kasper-Giebl, Anne;  Daellenbach, Kaspar R.;  Chen, Mindong;  Ge, Xinlei;  Baltensperger, Urs;  Prevot, Andre S. H.;  Slowik, Jay G.
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/09
Development of an inactivated vaccine candidate for SARS-CoV-2 期刊论文
Science, 2020
作者:  Qiang Gao;  Linlin Bao;  Haiyan Mao;  Lin Wang;  Kangwei Xu;  Minnan Yang;  Yajing Li;  Ling Zhu;  Nan Wang;  Zhe Lv;  Hong Gao;  Xiaoqin Ge;  Biao Kan;  Yaling Hu;  Jiangning Liu;  Fang Cai;  Deyu Jiang;  Yanhui Yin;  Chengfeng Qin;  Jing Li;  Xuejie Gong;  Xiuyu Lou;  Wen Shi;  Dongdong Wu;  Hengming Zhang;  Lang Zhu;  Wei Deng;  Yurong Li;  Jinxing Lu;  Changgui Li;  Xiangxi Wang;  Weidong Yin;  Yanjun Zhang;  Chuan Qin
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/06
Improved protein structure prediction using potentials from deep learning 期刊论文
NATURE, 2020, 577 (7792) : 706-+
作者:  Ma, Runze;  Cao, Duanyun;  Zhu, Chongqin;  Tian, Ye;  Peng, Jinbo;  Guo, Jing;  Chen, Ji;  Li, Xin-Zheng;  Francisco, Joseph S.;  Zeng, Xiao Cheng;  Xu, Li-Mei;  Wang, En-Ge;  Jiang, Ying
收藏  |  浏览/下载:157/0  |  提交时间:2020/07/03

Protein structure prediction can be used to determine the three-dimensional shape of a protein from its amino acid sequence(1). This problem is of fundamental importance as the structure of a protein largely determines its function(2)  however, protein structures can be difficult to determine experimentally. Considerable progress has recently been made by leveraging genetic information. It is possible to infer which amino acid residues are in contact by analysing covariation in homologous sequences, which aids in the prediction of protein structures(3). Here we show that we can train a neural network to make accurate predictions of the distances between pairs of residues, which convey more information about the structure than contact predictions. Using this information, we construct a potential of mean force(4) that can accurately describe the shape of a protein. We find that the resulting potential can be optimized by a simple gradient descent algorithm to generate structures without complex sampling procedures. The resulting system, named AlphaFold, achieves high accuracy, even for sequences with fewer homologous sequences. In the recent Critical Assessment of Protein Structure Prediction(5) (CASP13)-a blind assessment of the state of the field-AlphaFold created high-accuracy structures (with template modelling (TM) scores(6) of 0.7 or higher) for 24 out of 43 free modelling domains, whereas the next best method, which used sampling and contact information, achieved such accuracy for only 14 out of 43 domains. AlphaFold represents a considerable advance in protein-structure prediction. We expect this increased accuracy to enable insights into the function and malfunction of proteins, especially in cases for which no structures for homologous proteins have been experimentally determined(7).


  
Responses of soil moisture to regional climate change over the Three Rivers Source Region on the Tibetan Plateau 期刊论文
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2019
作者:  Deng, Mingshan;  Meng, Xianhong;  Li, Zhaoguo;  Lyv, Yaqiong;  Lei, Huajin;  Zhao, Lin;  Zhao, Shengnan;  Ge, Jun;  Jing, Hui
收藏  |  浏览/下载:21/0  |  提交时间:2019/11/27
land surface model data  precipitation  reanalysis data  soil moisture  temperature  Three Rivers Source region  
Linkages between mid-latitude cirrus cloud properties and large-scale meteorology at the SACOL site 期刊论文
CLIMATE DYNAMICS, 2019, 53: 5035-5046
作者:  Ge, Jinming;  Wang, Zhenquan;  Liu, Yuanyong;  Su, Jing;  Wang, Chen;  Dong, Zixiang
收藏  |  浏览/下载:19/0  |  提交时间:2019/11/27
Midlatitude  Cirrus cloud  Linkages  Large-scale meteorology  SACOL  
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  Zhu, Rongxuan;  Gires, Olivier;  Zhu, Liqun;  Liu, Jun;  Li, Junjian;  Yang, Hao;  Ju, Gaoda;  Huang, Jing;  Ge, Weiyu;  Chen, Yi;  Lu, Zhimin;  Wang, Hongxia
收藏  |  浏览/下载:21/0  |  提交时间:2019/11/27
Effect of Tibetan Plateau heating on summer extreme precipitation in eastern China 期刊论文
ATMOSPHERIC RESEARCH, 2019, 218: 364-371
作者:  Ge, Jing;  You, Qinglong;  Zhang, Yuqing
收藏  |  浏览/下载:17/0  |  提交时间:2019/04/09
Tibetan Plateau  Diabatic heating  South Asian High  Extreme precipitation  
Contrasting responses of autumn-leaf senescence to daytime and night-time warming (vol 8, pg 1092, 2018) 期刊论文
NATURE CLIMATE CHANGE, 2019, 9 (2) : 177-177
作者:  Wu, Chaoyang;  Wang, Xiaoyue;  Wang, Huanjiong;  Ciais, Philippe;  Penuelas, Josep;  Myneni, Ranga B.;  Desai, Ankur R.;  Gough, Christopher M.;  Gonsamo, Alemu;  Black, Andrew T.;  Jassal, Rachhpal S.;  Ju, Weimin;  Yuan, Wenping;  Fu, Yongshuo;  Shen, Miaogen;  Li, Shihua;  Liu, Ronggao;  Chen, Jing M.;  Ge, Quansheng
收藏  |  浏览/下载:29/0  |  提交时间:2019/04/09