资源环境科技发展态势分析平台(GSTDTAP): 检索

Guidelines for Modeling and Reporting Health Effects of Climate Change Mitigation Actions 期刊论文
Environmental Health Perspectives, 2020
作者: Jeremy J. Hess; Nikhil Ranadive; Chris Boyer; Lukasz Aleksandrowicz; Susan C. Anenberg; Kristin Aunan; Kristine Belesova; Michelle L. Bell; Sam Bickersteth; Kathryn Bowen; Marci Burden; Diarmid Campbell-Lendrum; Elizabeth Carlton; Guéladio Cissé; Francois Cohen; Hancheng Dai; Alan David Dangour; Purnamita Dasgupta; Howard Frumkin; Peng Gong; Robert J. Gould; Andy Haines; Simon Hales; Ian Hamilton; Tomoko Hasegawa; Masahiro Hashizume; Yasushi Honda; Daniel E. Horton; Alexandra Karambelas; Ho Kim; Satbyul Estella Kim; Patrick L. Kinney; Inza Kone; Kim Knowlton; Jos Lelieveld; Vijay S. Limaye; Qiyong Liu; Lina Madaniyazi; Micaela Elvira Martinez; Denise L. Mauzerall; James Milner; Tara Neville; Mark Nieuwenhuijsen; Shonali Pachauri; Frederica Perera; Helen Pineo; Justin V. Remais; Rebecca K. Saari; Jon Sampedro; Pauline Scheelbeek; Joel Schwartz; Drew Shindell; Priya Shyamsundar; Timothy J. Taylor; Cathryn Tonne; Detlef Van Vuuren; Can Wang; Nicholas Watts; J. Jason West; Paul Wilkinson; Stephen A. Wood; James Woodcock; Alistair Woodward; Yang Xie; Ying Zhang; Kristie L. Ebi

收藏 | 浏览/下载：18/0 | 提交时间：2020/11/20

Electron Inflow Velocities and Reconnection Rates at Earth's Magnetopause and Magnetosheath 期刊论文
Geophysical Research Letters, 2020
作者: J. L. Burch; J. M. Webster; M. Hesse; K. J. Genestreti; R. E. Denton; T. D. Phan; H. Hasegawa; P. A. Cassak; R. B. Torbert; B. L. Giles; D. J. Gershman; R. E. Ergun; C. T. Russell; R. J. Strangeway; O. Le Contel; K. R. Pritchard; A. T. Marshall; K.‐; J. Hwang; K. Dokgo; S. A. Fuselier; L.‐; J. Chen; S. Wang; M. Swisdak; J. F. Drake; M. R. Argall; K. J. Trattner; M. Yamada; G. Paschmann

收藏 | 浏览/下载：14/0 | 提交时间：2020/08/25

Pharmacologic fibroblast reprogramming into photoreceptors restores vision 期刊论文
NATURE, 2020, 581 (7806) : 83-+
作者: Jiang, Mingkai; Medlyn, Belinda E.; Drake, John E.; Duursma, Remko A.; Anderson, Ian C.; Barton, Craig V. M.; Boer, Matthias M.; Carrillo, Yolima; Castaneda-Gomez, Laura; Collins, Luke; Crous, Kristine Y.; De Kauwe, Martin G.; dos Santos, Bruna M.; Emmerson, Kathryn M.; Facey, Sarah L.; Gherlenda, Andrew N.; Gimeno, Teresa E.; Hasegawa, Shun; Johnson, Scott N.; Kannaste, Astrid; Macdonald, Catriona A.; Mahmud, Kashif; Moore, Ben D.; Nazaries, Loic; Neilson, Elizabeth H. J.; Nielsen, Uffe N.; Niinemets, Ulo; Noh, Nam Jin; Ochoa-Hueso, Raul; Pathare, Varsha S.; Pendall, Elise; Pihlblad, Johanna; Pineiro, Juan; Powell, Jeff R.; Power, Sally A.; Reich, Peter B.; Renchon, Alexandre A.; Riegler, Markus; Rinnan, Riikka; Rymer, Paul D.; Salomon, Roberto L.; Singh, Brajesh K.; Smith, Benjamin; Tjoelker, Mark G.; Walker, Jennifer K. M.; Wujeska-Klause, Agnieszka; Yang, Jinyan; Zaehle, Soenke; Ellsworth, David S.

收藏 | 浏览/下载：46/0 | 提交时间：2020/07/03

Photoreceptor loss is the final common endpoint in most retinopathies that lead to irreversible blindness, and there are no effective treatments to restore vision(1,2). Chemical reprogramming of fibroblasts offers an opportunity to reverse vision loss however, the generation of sensory neuronal subtypes such as photoreceptors remains a challenge. Here we report that the administration of a set of five small molecules can chemically induce the transformation of fibroblasts into rod photoreceptor-like cells. The transplantation of these chemically induced photoreceptor-like cells (CiPCs) into the subretinal space of rod degeneration mice (homozygous for rd1, also known as Pde6b) leads to partial restoration of the pupil reflex and visual function. We show that mitonuclear communication is a key determining factor for the reprogramming of fibroblasts into CiPCs. Specifically, treatment with these five compounds leads to the translocation of AXIN2 to the mitochondria, which results in the production of reactive oxygen species, the activation of NF-kappa B and the upregulation of Ascl1. We anticipate that CiPCs could have therapeutic potential for restoring vision.

A set of five small molecules can induce the transformation of fibroblasts into rod photoreceptor-like cells, which can partially restore pupil reflex and visual function when transplanted into a rod degeneration mouse model.

On the Ubiquity of Magnetic Reconnection Inside Flux Transfer Event-Like Structures at the Earth's Magnetopause 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (6)
作者: Fargette, N.; Lavraud, B.; Oieroset, M.; Phan, T. D.; Toledo-Redondo, S.; Kieokaew, R.; Jacquey, C.; Fuselier, S. A.; Trattner, K. J.; Petrinec, S.; Hasegawa, H.; Garnier, P.; Genot, V; Lenouvel, Q.; Fadanelli, S.; Penou, E.; Sauvaud, J. A.; Avanov, D. L. A.; Burch, J.; Chandler, M. O.; Coffey, V. N.; Dorelli, J.; Eastwood, J. P.; Farrugia, C. J.; Gershman, D. J.; Giles, B. L.; Grigorenko, E.; Moore, T. E.; Paterson, W. R.; Pollock, C.; Saito, Y.; Schiff, C.; Smith, S. E.

收藏 | 浏览/下载：13/0 | 提交时间：2020/07/02

Lactose drives Enterococcus expansion to promote graft-versus-host disease 期刊论文
SCIENCE, 2019, 366 (6469) : 1143-+
作者: Stein-Thoeringer, C. K.; Nichols, K. B.; Lazrak, A.; Docampo, M. D.; Slingerland, A. E.; Slingerland, J. B.; Clurman, A. G.; Armijo, G.; Gomes, A. L. C.; Shono, Y.; Staffas, A.; da Silva, M. Burgos; Devlin, S. M.; Markey, K. A.; Bajic, D.; Pinedo, R.; Tsakmaklis, A.; Littmann, E. R.; Pastore, A.; Taur, Y.; Monette, S.; Arcila, M. E.; Pickard, A. J.; Maloy, M.; Wright, R. J.; Amoretti, L. A.; Fontana, E.; Pham, D.; Jamal, M. A.; Weber, D.; Sung, A. D.; Hashimoto, D.; Scheid, C.; Xavier, J. B.; Messina, J. A.; Romero, K.; Lew, M.; Bush, A.; Bohannon, L.; Hayasaka, K.; Hasegawa, Y.; Vehreschild, M. J. G. T.; Cross, J. R.; Ponce, D. M.; Perales, M. A.; Giralt, S. A.; Jenq, R. R.; Teshima, T.; Holler, E.; Chao, N. J.; Pamer, E. G.; Peled, J. U.; van den Brink, M. R. M.

收藏 | 浏览/下载：14/0 | 提交时间：2020/02/17

The geomorphology, color, and thermal properties of Ryugu: Implications for parent-body processes 期刊论文
SCIENCE, 2019, 364 (6437) : 252-+
作者: Sugita, S.; Honda, R.; Morota, T.; Kameda, S.; Sawada, H.; Tatsumi, E.; Yamada, M.; Honda, C.; Yokota, Y.; Kouyama, T.; Sakatani, N.; Ogawa, K.; Suzuki, H.; Okada, T.; Namiki, N.; Tanaka, S.; Iijima, Y.; Yoshioka, K.; Hayakawa, M.; Cho, Y.; Matsuoka, M.; Hirata, N.; Hirata, N.; Miyamoto, H.; Domingue, D.; Hirabayashi, M.; Nakamura, T.; Hiroi, T.; Michikami, T.; Michel, P.; Ballouz, R. -L.; Barnouin, O. S.; Ernst, C. M.; Schroeder, S. E.; Kikuchi, H.; Hemmi, R.; Komatsu, G.; Fukuhara, T.; Taguchi, M.; Arai, T.; Senshu, H.; Demura, H.; Ogawa, Y.; Shimaki, Y.; Sekiguchi, T.; Mueller, T. G.; Hagermann, A.; Mizuno, T.; Noda, H.; Matsumoto, K.; Yamada, R.; Ishihara, Y.; Ikeda, H.; Araki, H.; Yamamoto, K.; Abe, S.; Yoshida, F.; Higuchi, A.; Sasaki, S.; Oshigami, S.; Tsuruta, S.; Asari, K.; Tazawa, S.; Shizugami, M.; Kimura, J.; Otsubo, T.; Yabuta, H.; Hasegawa, S.; Ishiguro, M.; Tachibana, S.; Palmer, E.; Gaskell, R.; Le Corre, L.; Jaumann, R.; Otto, K.; Schmitz, N.; Abell, P. A.; Barucci, M. A.; Zolensky, M. E.; Vilas, F.; Thuillet, F.; Sugimoto, C.; Takaki, N.; Suzuki, Y.; Kamiyoshihara, H.; Okada, M.; Nagata, K.; Fujimoto, M.; Yoshikawa, M.; Yamamoto, Y.; Shirai, K.; Noguchi, R.; Ogawa, N.; Terui, F.; Kikuchi, S.; Yamaguchi, T.; Oki, Y.; Takao, Y.; Takeuchi, H.; Ono, G.; Mimasu, Y.; Yoshikawa, K.; Takahashi, T.; Takei, Y.; Fujii, A.; Hirose, C.; Nakazawa, S.; Hosoda, S.; Mori, O.; Shimada, T.; Soldini, S.; Iwata, T.; Abe, M.; Yano, H.; Tsukizaki, R.; Ozaki, M.; Nishiyama, K.; Saiki, T.; Watanabe, S.; Tsuda, Y.

收藏 | 浏览/下载：10/0 | 提交时间：2019/11/27

Direct measurements of two-way wave-particle energy transfer in a collisionless space plasma 期刊论文
SCIENCE, 2018, 361 (6406) : 1000-1003
作者: Kitamura, N.; Kitahara, M.; Shoji, M.; Miyoshi, Y.; Hasegawa, H.; Nakamura, S.; Katoh, Y.; Saito, Y.; Yokota, S.; Gershman, D. J.; Vinas, A. F.; Giles, B. L.; Moore, T. E.; Paterson, W. R.; Pollock, C. J.; Russell, C. T.; Strangeway, R. J.; Fuselier, S. A.; Burch, J. L.

收藏 | 浏览/下载：17/0 | 提交时间：2019/11/27

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