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Krüppel-like factor 1 is a core cardiomyogenic trigger in zebrafish 期刊论文
Science, 2021
作者:  Masahito Ogawa;  Fan-Suo Geng;  David T. Humphreys;  Esther Kristianto;  Delicia Z. Sheng;  Subhra P. Hui;  Yuxi Zhang;  Kotaro Sugimoto;  Maki Nakayama;  Dawei Zheng;  Daniel Hesselson;  Mark P. Hodson;  Ozren Bogdanovic;  Kazu Kikuchi
收藏  |  浏览/下载:22/0  |  提交时间:2021/04/12
Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth 期刊论文
Science, 2021
作者:  Ryan S. Roark;  Hui Li;  Wilton B. Williams;  Hema Chug;  Rosemarie D. Mason;  Jason Gorman;  Shuyi Wang;  Fang-Hua Lee;  Juliette Rando;  Mattia Bonsignori;  Kwan-Ki Hwang;  Kevin O. Saunders;  Kevin Wiehe;  M. Anthony Moody;  Peter T. Hraber;  Kshitij Wagh;  Elena E. Giorgi;  Ronnie M. Russell;  Frederic Bibollet-Ruche;  Weimin Liu;  Jesse Connell;  Andrew G. Smith;  Julia DeVoto;  Alexander I. Murphy;  Jessica Smith;  Wenge Ding;  Chengyan Zhao;  Neha Chohan;  Maho Okumura;  Christina Rosario;  Yu Ding;  Emily Lindemuth;  Anya M. Bauer;  Katharine J. Bar;  David Ambrozak;  Cara W. Chao;  Gwo-Yu Chuang;  Hui Geng;  Bob C. Lin;  Mark K. Louder;  Richard Nguyen;  Baoshan Zhang;  Mark G. Lewis;  Donald D. Raymond;  Nicole A. Doria-Rose;  Chaim A. Schramm;  Daniel C. Douek;  Mario Roederer;  Thomas B. Kepler;  Garnett Kelsoe;  John R. Mascola;  Peter D. Kwong;  Bette T. Korber;  Stephen C. Harrison;  Barton F. Haynes;  Beatrice H. Hahn;  George M. Shaw
收藏  |  浏览/下载:59/0  |  提交时间:2021/01/15
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy 期刊论文
Science, 2020
作者:  Hongjing Gu;  Qi Chen;  Guan Yang;  Lei He;  Hang Fan;  Yong-Qiang Deng;  Yanxiao Wang;  Yue Teng;  Zhongpeng Zhao;  Yujun Cui;  Yuchang Li;  Xiao-Feng Li;  Jiangfan Li;  Na-Na Zhang;  Xiaolan Yang;  Shaolong Chen;  Yan Guo;  Guangyu Zhao;  Xiliang Wang;  De-Yan Luo;  Hui Wang;  Xiao Yang;  Yan Li;  Gencheng Han;  Yuxian He;  Xiaojun Zhou;  Shusheng Geng;  Xiaoli Sheng;  Shibo Jiang;  Shihui Sun;  Cheng-Feng Qin;  Yusen Zhou
收藏  |  浏览/下载:42/0  |  提交时间:2020/09/30
Exposure to air pollution and scarlet fever resurgence in China: a six-year surveillance study 期刊论文
Nature Communications, 2020
作者:  Yonghong Liu;  Hui Ding;  Shu-ting Chang;  Ran Lu;  Hui Zhong;  Na Zhao;  Tzu-Hsuan Lin;  Yiming Bao;  Liwei Yap;  Weijia Xu;  Minyi Wang;  Yuan Li;  Shuwen Qin;  Yu Zhao;  Xingyi Geng;  Supen Wang;  Enfu Chen;  Zhi Yu;  Ta-Chien Chan;  Shelan Liu
收藏  |  浏览/下载:38/0  |  提交时间:2020/09/08
Recycling and metabolic flexibility dictate life in the lower oceanic crust 期刊论文
NATURE, 2020, 579 (7798) : 250-+
作者:  Zhou, Peng;  Yang, Xing-Lou;  Wang, Xian-Guang;  Hu, Ben;  Zhang, Lei;  Zhang, Wei;  Si, Hao-Rui;  Zhu, Yan;  Li, Bei;  Huang, Chao-Lin;  Chen, Hui-Dong;  Chen, Jing;  Luo, Yun;  Guo, Hua;  Jiang, Ren-Di;  Liu, Mei-Qin;  Chen, Ying;  Shen, Xu-Rui;  Wang, Xi;  Zheng, Xiao-Shuang;  Zhao, Kai;  Chen, Quan-Jiao;  Deng, Fei;  Liu, Lin-Lin;  Yan, Bing;  Zhan, Fa-Xian;  Wang, Yan-Yi;  Xiao, Geng-Fu;  Shi, Zheng-Li
收藏  |  浏览/下载:60/0  |  提交时间:2020/05/13

The lithified lower oceanic crust is one of Earth'  s last biological frontiers as it is difficult to access. It is challenging for microbiota that live in marine subsurface sediments or igneous basement to obtain sufficient carbon resources and energy to support growth(1-3) or to meet basal power requirements(4) during periods of resource scarcity. Here we show how limited and unpredictable sources of carbon and energy dictate survival strategies used by low-biomass microbial communities that live 10-750 m below the seafloor at Atlantis Bank, Indian Ocean, where Earth'  s lower crust is exposed at the seafloor. Assays of enzyme activities, lipid biomarkers, marker genes and microscopy indicate heterogeneously distributed and viable biomass with ultralow cell densities (fewer than 2,000 cells per cm(3)). Expression of genes involved in unexpected heterotrophic processes includes those with a role in the degradation of polyaromatic hydrocarbons, use of polyhydroxyalkanoates as carbon-storage molecules and recycling of amino acids to produce compounds that can participate in redox reactions and energy production. Our study provides insights into how microorganisms in the plutonic crust are able to survive within fractures or porous substrates by coupling sources of energy to organic and inorganic carbon resources that are probably delivered through the circulation of subseafloor fluids or seawater.


  
The gut microbiome in atherosclerotic cardiovascular disease 期刊论文
NATURE COMMUNICATIONS, 2017, 8
作者:  Jie, Zhuye;  Xia, Huihua;  Zhong, Shi-Long;  Feng, Qiang;  Li, Shenghui;  Liang, Suisha;  Zhong, Huanzi;  Liu, Zhipeng;  Gao, Yuan;  Zhao, Hui;  Zhang, Dongya;  Su, Zheng;  Fang, Zhiwei;  Lan, Zhou;  Li, Junhua;  Xiao, Liang;  Li, Jun;  Li, Ruijun;  Li, Xiaoping;  Li, Fei;  Ren, Huahui;  Huang, Yan;  Peng, Yangqing;  Li, Guanglei;  Wen, Bo;  Dong, Bo;  Chen, Ji-Yan;  Geng, Qing-Shan;  Zhang, Zhi-Wei;  Yang, Huanming;  Wang, Jian;  Wang, Jun;  Zhang, Xuan;  Madsen, Lise;  Brix, Susanne;  Ning, Guang;  Xu, Xun;  Liu, Xin;  Hou, Yong;  Jia, Huijue;  He, Kunlun;  Kristiansen, Karsten
收藏  |  浏览/下载:39/0  |  提交时间:2019/11/27
基于先进地震成像和大地测量反演算法确定智利地区高分辨地壳结构及其变形特征 项目
项目编号:41861134009; 经费:2957200(CNY); 起止日期:2018 / dc_date_end
项目负责人:  耿江辉
收藏  |  浏览/下载:27/0  |  提交时间:2019/11/27
Isotopic constraints on heterogeneous sulfate production in Beijing haze 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2018, 18 (8) : 5515-5528
作者:  He, Pengzhen;  Alexander, Becky;  Geng, Lei;  Chi, Xiyuan;  Fan, Shidong;  Zhan, Haicong;  Kang, Hui;  Zheng, Guangjie;  Cheng, Yafang;  Su, Hang;  Liu, Cheng;  Xie, Zhouqing
收藏  |  浏览/下载:25/0  |  提交时间:2019/04/09
多系统多频率GNSS广域精密单点定位模糊度快速固定理论和方法 项目
项目编号:41674033; 经费:680000(CNY); 起止日期:2017 / dc_date_end
项目负责人:  耿江辉
收藏  |  浏览/下载:10/0  |  提交时间:2019/04/11