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Haplotype-resolved diverse human genomes and integrated analysis of structural variation 期刊论文
Science, 2021
作者:  Peter Ebert;  Peter A. Audano;  Qihui Zhu;  Bernardo Rodriguez-Martin;  David Porubsky;  Marc Jan Bonder;  Arvis Sulovari;  Jana Ebler;  Weichen Zhou;  Rebecca Serra Mari;  Feyza Yilmaz;  Xuefang Zhao;  PingHsun Hsieh;  Joyce Lee;  Sushant Kumar;  Jiadong Lin;  Tobias Rausch;  Yu Chen;  Jingwen Ren;  Martin Santamarina;  Wolfram Höps;  Hufsah Ashraf;  Nelson T. Chuang;  Xiaofei Yang;  Katherine M. Munson;  Alexandra P. Lewis;  Susan Fairley;  Luke J. Tallon;  Wayne E. Clarke;  Anna O. Basile;  Marta Byrska-Bishop;  André Corvelo;  Uday S. Evani;  Tsung-Yu Lu;  Mark J. P. Chaisson;  Junjie Chen;  Chong Li;  Harrison Brand;  Aaron M. Wenger;  Maryam Ghareghani;  William T. Harvey;  Benjamin Raeder;  Patrick Hasenfeld;  Allison A. Regier;  Haley J. Abel;  Ira M. Hall;  Paul Flicek;  Oliver Stegle;  Mark B. Gerstein;  Jose M. C. Tubio;  Zepeng Mu;  Yang I. Li;  Xinghua Shi;  Alex R. Hastie;  Kai Ye;  Zechen Chong;  Ashley D. Sanders;  Michael C. Zody;  Michael E. Talkowski;  Ryan E. Mills;  Scott E. Devine;  Charles Lee;  Jan O. Korbel;  Tobias Marschall;  Evan E. Eichler
收藏  |  浏览/下载:65/0  |  提交时间:2021/04/06
End of Green Sahara amplified mid-聽to late Holocene megadroughts in mainland Southeast Asia 期刊论文
Nature Communications, 2020
作者:  Michael L. Griffiths;  Kathleen R. Johnson;  Francesco S. R. Pausata;  Joyce C. White;  Gideon M. Henderson;  Christopher T. Wood;  Hongying Yang;  Vasile Ersek;  Cyler Conrad;  Natasha Sekhon
收藏  |  浏览/下载:22/0  |  提交时间:2020/08/25
Hydrothermal (NN)-N-15-N-15 abundances constrain the origins of mantle nitrogen 期刊论文
NATURE, 2020, 580 (7803) : 367-+
作者:  Zhao, Steven;  Jang, Cholsoon;  Liu, Joyce;  Uehara, Kahealani;  Gilbert, Michael;  Izzo, Luke;  Zeng, Xianfeng;  Trefely, Sophie;  Fernandez, Sully;  Carrer, Alessandro;  Miller, Katelyn D.;  Schug, Zachary T.;  Snyder, Nathaniel W.;  Gade, Terence P.;  Titchenell, Paul M.;  Rabinowitz, Joshua D.;  Wellen, Kathryn E.
收藏  |  浏览/下载:36/0  |  提交时间:2020/05/13

Nitrogen is the main constituent of the Earth'  s atmosphere, but its provenance in the Earth'  s mantle remains uncertain. The relative contribution of primordial nitrogen inherited during the Earth'  s accretion versus that subducted from the Earth'  s surface is unclear(1-6). Here we show that the mantle may have retained remnants of such primordial nitrogen. We use the rare (NN)-N-15-N-15 isotopologue of N-2 as a new tracer of air contamination in volcanic gas effusions. By constraining air contamination in gases from Iceland, Eifel (Germany) and Yellowstone (USA), we derive estimates of mantle delta N-15 (the fractional difference in N-15/N-14 from air), N-2/Ar-36 and N-2/He-3. Our results show that negative delta N-15 values observed in gases, previously regarded as indicating a mantle origin for nitrogen(7-10), in fact represent dominantly air-derived N-2 that experienced N-15/N-14 fractionation in hydrothermal systems. Using two-component mixing models to correct for this effect, the (NN)-N-15-N-15 data allow extrapolations that characterize mantle endmember delta N-15, N-2/Ar-36 and N-2/He-3 values. We show that the Eifel region has slightly increased delta N-15 and N-2/Ar-36 values relative to estimates for the convective mantle provided by mid-ocean-ridge basalts(11), consistent with subducted nitrogen being added to the mantle source. In contrast, we find that whereas the Yellowstone plume has delta N-15 values substantially greater than that of the convective mantle, resembling surface components(12-15), its N-2/Ar-36 and N-2/He-3 ratios are indistinguishable from those of the convective mantle. This observation raises the possibility that the plume hosts a primordial component. We provide a test of the subduction hypothesis with a two-box model, describing the evolution of mantle and surface nitrogen through geological time. We show that the effect of subduction on the deep nitrogen cycle may be less important than has been suggested by previous investigations. We propose instead that high mid-ocean-ridge basalt and plume delta N-15 values may both be dominantly primordial features.


  
Design of an invitro biocatalytic cascade for the manufacture of islatravir 期刊论文
SCIENCE, 2019, 366 (6470) : 1255-+
作者:  Huffman, Mark A.;  Fryszkowska, Anna;  Alvizo, Oscar;  Borra-Garske, Margie;  Campos, Kevin R.;  Canada, Keith A.;  Devine, Paul N.;  Duan, Da;  Forstater, Jacob H.;  Grosser, Shane T.;  Halsey, Holst M.;  Hughes, Gregory J.;  Jo, Junyong;  Joyce, Leo A.;  Kolev, Joshua N.;  Liang, Jack;  Maloney, Kevin M.;  Mann, Benjamin F.;  Marshall, Nicholas M.;  McLaughlin, Mark;  Moore, Jeffrey C.;  Murphy, Grant S.;  Nawrat, Christopher C.;  Nazor, Jovana;  Novick, Scott;  Patel, Niki R.;  Rodriguez-Granillo, Agustina;  Robaire, Sandra A.;  Sherer, Edward C.;  Truppo, Matthew D.;  Whittaker, Aaron M.;  Verma, Deeptak;  Xiao, Li;  Xu, Yingju;  Yang, Hao
收藏  |  浏览/下载:48/0  |  提交时间:2020/02/17
Gulf Stream Variability in the Context of Quasi-Decadal and Multidecadal Atlantic Climate Variability 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2018, 45 (20) : 11257-11264
作者:  McCarthy, G. D.;  Joyce, T. M.;  Josey, S. A.
收藏  |  浏览/下载:10/0  |  提交时间:2019/04/09
High-resolution comparative analysis of great ape genomes 期刊论文
SCIENCE, 2018, 360 (6393) : 1085-+
作者:  Kronenberg, Zev N.;  Fiddes, Ian T.;  Gordon, David;  Murali, Shwetha;  Cantsilieris, Stuart;  Meyerson, Olivia S.;  Underwood, Jason G.;  Nelson, Bradley J.;  Chaisson, Mark J. P.;  Dougherty, Max L.;  Munson, Katherine M.;  Hastie, Alex R.;  Diekhans, Mark;  Hormozdiari, Fereydoun;  Lorusso, Nicola;  Hoekzema, Kendra;  Qiu, Ruolan;  Clark, Karen;  Raja, Archana;  Welch, AnneMarie E.;  Sorensen, Melanie;  Baker, Carl;  Fulton, Robert S.;  Armstrong, Joel;  Graves-Lindsay, Tina A.;  Denli, Ahmet M.;  Hoppe, Emma R.;  Hsieh, PingHsun;  Hill, Christopher M.;  Pang, Andy Wing Chun;  Lee, Joyce;  Lam, Ernest T.;  Dutcher, Susan K.;  Gage, Fred H.;  Warren, Wesley C.;  Shendure, Jay;  Haussler, David;  Schneider, Valerie A.;  Cao, Han;  Ventura, Mario;  Wilson, Richard K.;  Paten, Benedict;  Pollen, Alex;  Eichler, Evan E.
收藏  |  浏览/下载:71/0  |  提交时间:2019/11/27
Massive Mortality of a Planktivorous Seabird in Response to a Marine Heatwave 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2018, 45 (7) : 3193-3202
作者:  Jones, Timothy;  Parrish, Julia K.;  Peterson, William T.;  Bjorkstedt, Eric P.;  Bond, Nicholas A.;  Ballance, Lisa T.;  Bowes, Victoria;  Hipfner, J. Mark;  Burgess, Hillary K.;  Dolliver, Jane E.;  Lindquist, Kirsten;  Lindsey, Jacqueline;  Nevins, Hannahrose M.;  Robertson, Roxanne R.;  Roletto, Jan;  Wilson, Laurie;  Joyce, Trevor;  Harvey, James
收藏  |  浏览/下载:21/0  |  提交时间:2019/04/09
Biochar built soil carbon over a decade by stabilizing rhizodeposits 期刊论文
NATURE CLIMATE CHANGE, 2017, 7 (5)
作者:  Weng, Zhe (Han);  Van Zwieten, Lukas;  Singh, Bhupinder Pal;  Tavakkoli, Ehsan;  Joseph, Stephen;  Macdonald, Lynne M.;  Rose, Terry J.;  Rose, Michael T.;  Kimber, Stephen W. L.;  Morris, Stephen;  Cozzolino, Daniel;  Araujo, Joyce R.;  Archanjo, Braulio S.;  Cowie, Annette
收藏  |  浏览/下载:30/0  |  提交时间:2019/04/09