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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 期刊论文
Science, 2021
作者:  Nir Drayman;  Jennifer K. DeMarco;  Krysten A. Jones;  Saara-Anne Azizi;  Heather M. Froggatt;  Kemin Tan;  Natalia Ivanovna Maltseva;  Siquan Chen;  Vlad Nicolaescu;  Steve Dvorkin;  Kevin Furlong;  Rahul S. Kathayat;  Mason R. Firpo;  Vincent Mastrodomenico;  Emily A. Bruce;  Madaline M. Schmidt;  Robert Jedrzejczak;  Miguel Á. Muñoz-Alía;  Brooke Schuster;  Vishnu Nair;  Kyu-yeon Han;  Amornrat O’Brien;  Anastasia Tomatsidou;  Bjoern Meyer;  Marco Vignuzzi;  Dominique Missiakas;  Jason W. Botten;  Christopher B. Brooke;  Hyun Lee;  Susan C. Baker;  Bryan C. Mounce;  Nicholas S. Heaton;  William E. Severson;  Kenneth E. Palmer;  Bryan C. Dickinson;  Andrzej Joachimiak;  Glenn Randall;  Savaş Tay
收藏  |  浏览/下载:13/0  |  提交时间:2021/08/25
The morphometry of impact craters on Bennu 期刊论文
Geophysical Research Letters, 2020
作者:  R. T. Daly;  E. B. Bierhaus;  O. S. Barnouin;  M. G. Daly;  J. A. Seabrook;  J. H. Roberts;  C. M. Ernst;  M. E. Perry;  H. Nair;  R. C. Espiritu;  E. E. Palmer;  R. W. Gaskell;  J. R. Weirich;  H. C. M. Susorney;  C. L. Johnson;  K. J. Walsh;  M. C. Nolan;  E. R. Jawin;  P. Michel;  D. Trang;  D. S. Lauretta
收藏  |  浏览/下载:16/0  |  提交时间:2020/11/24
Author Correction: Shape of (101955) Bennu indicative of a rubble pile with internal stiffness 期刊论文
Nature, 2020
作者:  O. S. Barnouin;  M. G. Daly;  E. E. Palmer;  R. W. Gaskell;  J. R. Weirich;  C. L. Johnson;  M. M. Al Asad;  J. H. Roberts;  M. E. Perry;  H. C. M. Susorney;  R. T. Daly;  E. B. Bierhaus;  J. A. Seabrook;  R. C. Espiritu;  A. H. Nair;  L. Nguyen;  G. A. Neumann;  C. M. Ernst;  W. V. Boynton;  M. C. Nolan;  C. D. Adam;  M. C. Moreau;  B. Rizk;  C. Y. Drouet D’;  Aubigny;  E. R. Jawin;  K. J. Walsh;  P. Michel;  S. R. Schwartz;  R.-L. Ballouz;  E. M. Mazarico;  D. J. Scheeres;  J. W. McMahon;  W. F. Bottke;  S. Sugita;  N. Hirata;  N. Hirata;  S.-i. Watanabe;  K. N. Burke;  D. N. DellaGiustina;  C. A. Bennett;  D. S. Lauretta
收藏  |  浏览/下载:10/0  |  提交时间:2020/09/08
Nutrients and water availability constrain the seasonality of vegetation activity in a Mediterranean ecosystem 期刊论文
Global Change Biology, 2020
作者:  Yunpeng Luo;  Tarek El‐;  Madany;  Xuanlong Ma;  Richard Nair;  Martin Jung;  Ulrich Weber;  Gianluca Filippa;  Solveig F. Bucher;  Gerardo Moreno;  Edoardo Cremonese;  Arnaud Carrara;  Rosario Gonzalez‐;  Cascon;  Yonatan Cá;  ceres Escudero;  Marta Galvagno;  Javier Pacheco‐;  Labrador;  M. Pilar Martí;  n;  Oscar Perez‐;  Priego;  Markus Reichstein;  Andrew D. Richardson;  Annette Menzel;  Christine Rö;  mermann;  Mirco Migliavacca
收藏  |  浏览/下载:14/0  |  提交时间:2020/06/01
The fate of carbon in a mature forest under carbon dioxide enrichment 期刊论文
NATURE, 2020, 580 (7802) : 227-+
作者:  Sun, P. Z.;  Yang, Q.;  Kuang, W. J.;  Stebunov, Y. V.;  Xiong, W. Q.;  Yu, J.;  Nair, R. R.;  Katsnelson, M. I.;  Yuan, S. J.;  Grigorieva, I. V.;  Lozada-Hidalgo, M.;  Wang, F. C.;  Geim, A. K.
收藏  |  浏览/下载:70/0  |  提交时间:2020/05/13

Carbon dioxide enrichment of a mature forest resulted in the emission of the excess carbon back into the atmosphere via enhanced ecosystem respiration, suggesting that mature forests may be limited in their capacity to mitigate climate change.


Atmospheric carbon dioxide enrichment (eCO(2)) can enhance plant carbon uptake and growth(1-5), thereby providing an important negative feedback to climate change by slowing the rate of increase of the atmospheric CO2 concentration(6). Although evidence gathered from young aggrading forests has generally indicated a strong CO2 fertilization effect on biomass growth(3-5), it is unclear whether mature forests respond to eCO(2) in a similar way. In mature trees and forest stands(7-10), photosynthetic uptake has been found to increase under eCO(2) without any apparent accompanying growth response, leaving the fate of additional carbon fixed under eCO(2) unclear(4,5,7-11). Here using data from the first ecosystem-scale Free-Air CO2 Enrichment (FACE) experiment in a mature forest, we constructed a comprehensive ecosystem carbon budget to track the fate of carbon as the forest responded to four years of eCO(2) exposure. We show that, although the eCO(2) treatment of +150 parts per million (+38 per cent) above ambient levels induced a 12 per cent (+247 grams of carbon per square metre per year) increase in carbon uptake through gross primary production, this additional carbon uptake did not lead to increased carbon sequestration at the ecosystem level. Instead, the majority of the extra carbon was emitted back into the atmosphere via several respiratory fluxes, with increased soil respiration alone accounting for half of the total uptake surplus. Our results call into question the predominant thinking that the capacity of forests to act as carbon sinks will be generally enhanced under eCO(2), and challenge the efficacy of climate mitigation strategies that rely on ubiquitous CO2 fertilization as a driver of increased carbon sinks in global forests.


  
Electrical manipulation of a topological antiferromagnetic state 期刊论文
NATURE, 2020, 580 (7805) : 608-+
作者:  Chabon, Jacob J.;  Hamilton, Emily G.;  Kurtz, David M.;  Esfahani, Mohammad S.;  Moding, Everett J.;  Stehr, Henning;  Schroers-Martin, Joseph;  Nabet, Barzin Y.;  Chen, Binbin;  Chaudhuri, Aadel A.;  Liu, Chih Long;  Hui, Angela B.;  Jin, Michael C.;  Azad, Tej D.;  Almanza, Diego;  Jeon, Young-Jun;  Nesselbush, Monica C.;  Keh, Lyron Co Ting;  Bonilla, Rene F.;  Yoo, Christopher H.;  Ko, Ryan B.;  Chen, Emily L.;  Merriott, David J.;  Massion, Pierre P.;  Mansfield, Aaron S.;  Jen, Jin;  Ren, Hong Z.;  Lin, Steven H.;  Costantino, Christina L.;  Burr, Risa;  Tibshirani, Robert;  Gambhir, Sanjiv S.;  Berry, Gerald J.;  Jensen, Kristin C.;  West, Robert B.;  Neal, Joel W.;  Wakelee, Heather A.;  Loo, Billy W., Jr.;  Kunder, Christian A.;  Leung, Ann N.;  Lui, Natalie S.;  Berry, Mark F.;  Shrager, Joseph B.;  Nair, Viswam S.;  Haber, Daniel A.;  Sequist, Lecia V.;  Alizadeh, Ash A.;  Diehn, Maximilian
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/03

Room-temperature electrical switching of a topological antiferromagnetic state in polycrystalline Mn3Sn thin films is demonstrated using the same protocol as that used for conventional ferromagnetic metals.


Electrical manipulation of phenomena generated by nontrivial band topology is essential for the development of next-generation technology using topological protection. A Weyl semimetal is a three-dimensional gapless system that hosts Weyl fermions as low-energy quasiparticles(1-4). It has various exotic properties, such as a large anomalous Hall effect (AHE) and chiral anomaly, which are robust owing to the topologically protected Weyl nodes(1-16). To manipulate such phenomena, a magnetic version of Weyl semimetals would be useful for controlling the locations of Weyl nodes in the Brillouin zone. Moreover, electrical manipulation of antiferromagnetic Weyl metals would facilitate the use of antiferromagnetic spintronics to realize high-density devices with ultrafast operation(17,18). However, electrical control of a Weyl metal has not yet been reported. Here we demonstrate the electrical switching of a topological antiferromagnetic state and its detection by the AHE at room temperature in a polycrystalline thin film(19) of the antiferromagnetic Weyl metal Mn3Sn9,10,12,20, which exhibits zero-field AHE. Using bilayer devices composed of Mn3Sn and nonmagnetic metals, we find that an electrical current density of about 10(10) to 10(11) amperes per square metre induces magnetic switching in the nonmagnetic metals, with a large change in Hall voltage. In addition, the current polarity along the bias field and the sign of the spin Hall angle of the nonmagnetic metals-positive for Pt (ref. (21)), close to 0 for Cu and negative for W (ref. (22))-determines the sign of the Hall voltage. Notably, the electrical switching in the antiferromagnet is achieved with the same protocol as that used for ferromagnetic metals(23,24). Our results may lead to further scientific and technological advances in topological magnetism and antiferromagnetic spintronics.


  
Cloud condensation nuclei properties of South Asian outflow over the northern Indian Ocean during winter 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (5) : 3135-3149
作者:  Nair, Vijayakumar S.;  Jayachandran, Venugopalan Nair;  Kompalli, Sobhan Kumar;  Gogoi, Mukunda M.;  Babu, S. Suresh
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/02
Altitude profiles of cloud condensation nuclei characteristics across the Indo-Gangetic Plain prior to the onset of the Indian summer monsoon 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (1) : 561-576
作者:  Jayachandran, Venugopalan Nair;  Babu, Surendran Nair Suresh;  Vaishya, Aditya;  Gogoi, Mukunda M.;  Nair, Vijayakumar S.;  Satheesh, Sreedharan Krishnakumari;  Moorthy, Krishnaswamy Krishna
收藏  |  浏览/下载:9/0  |  提交时间:2020/05/13
Altitude profiles of cloud condensation nuclei characteristics across the Indo-Gangetic Plain prior to the onset of the Indian summer monsoon 期刊论文
Atmospheric Chemistry and Physics, 2020
作者:  Venugopalan Nair Jayachandran, Surendran Nair Suresh Babu, Aditya Vaishya, Mukunda M. Gogoi, Vijayakumar S. Nair, Sreedharan Krishnakumari Satheesh, and Krishnaswamy Krishna Moorthy
收藏  |  浏览/下载:8/0  |  提交时间:2020/08/18
Sensitivity of climate models in relation to the "pool of inhibited cloudiness" over South of the Bay of Bengal 期刊论文
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2019
作者:  Roy, Kumar;  Mukhopadhyay, Parthasarathi;  Murali Krishna, Ravuri Phani;  Ganai, Malay;  Mahakur, Mata;  Narayan Rao, Thota;  Nair, Anish K. M.;  Ramakrishna, Surireddi Satya Venkata Siva
收藏  |  浏览/下载:13/0  |  提交时间:2020/02/17
cloud and convection process parameterization  fidelity of CMIP5 and CFSv2 models  pool of inhibited cloudiness