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利用投入产出分析法对英国海洋经济贡献度进行了新的评估 快报文章
资源环境快报，2020年第15期
作者:  王金平,薛明媚
Microsoft Word(16Kb)  |  收藏  |  浏览/下载：369/1  |  提交时间：2020/08/16
Input-output method  Marine economy  assessment  
Improved protein structure prediction using potentials from deep learning 期刊论文
NATURE, 2020, 577 (7792) : 706-+
作者:  Ma, Runze;  Cao, Duanyun;  Zhu, Chongqin;  Tian, Ye;  Peng, Jinbo;  Guo, Jing;  Chen, Ji;  Li, Xin-Zheng;  Francisco, Joseph S.;  Zeng, Xiao Cheng;  Xu, Li-Mei;  Wang, En-Ge;  Jiang, Ying
收藏  |  浏览/下载：156/0  |  提交时间：2020/07/03

Protein structure prediction can be used to determine the three-dimensional shape of a protein from its amino acid sequence(1). This problem is of fundamental importance as the structure of a protein largely determines its function(2)  however, protein structures can be difficult to determine experimentally. Considerable progress has recently been made by leveraging genetic information. It is possible to infer which amino acid residues are in contact by analysing covariation in homologous sequences, which aids in the prediction of protein structures(3). Here we show that we can train a neural network to make accurate predictions of the distances between pairs of residues, which convey more information about the structure than contact predictions. Using this information, we construct a potential of mean force(4) that can accurately describe the shape of a protein. We find that the resulting potential can be optimized by a simple gradient descent algorithm to generate structures without complex sampling procedures. The resulting system, named AlphaFold, achieves high accuracy, even for sequences with fewer homologous sequences. In the recent Critical Assessment of Protein Structure Prediction(5) (CASP13)-a blind assessment of the state of the field-AlphaFold created high-accuracy structures (with template modelling (TM) scores(6) of 0.7 or higher) for 24 out of 43 free modelling domains, whereas the next best method, which used sampling and contact information, achieved such accuracy for only 14 out of 43 domains. AlphaFold represents a considerable advance in protein-structure prediction. We expect this increased accuracy to enable insights into the function and malfunction of proteins, especially in cases for which no structures for homologous proteins have been experimentally determined(7).


  
Probabilistic Assessment of Flood Hazard due to Levee Breaches Using Fragility Functions 期刊论文
WATER RESOURCES RESEARCH, 2019
作者:  D&;  39;Oria, M.
收藏  |  浏览/下载：5/0  |  提交时间：2020/02/16
Flood hazard assessment  Probabilistic method  Levee breaches  Fragility functions  Piping  Case study  
Probabilistic Forecast of Single-Phase Flow in Porous Media With Uncertain Properties 期刊论文
WATER RESOURCES RESEARCH, 2019
作者:  Yang, Hyung Jun;  Boso, Francesca;  Tchelepi, Hamdi A.;  Tartakovsky, Daniel M.
收藏  |  浏览/下载：14/0  |  提交时间：2019/11/27
uncertainty quantification  groundwater flow  random conductivity  method of distributions  risk assessment  rare events  
Synthesis and Review: an inter-method comparison of climate change impacts on agriculture 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2018, 13 (7)
作者:  Ciscar, Juan-Carlos;  Fisher-Vanden, Karen;  Lobell, David B.
收藏  |  浏览/下载：10/0  |  提交时间：2019/04/09
agriculture climate impacts  process models  statistical models  integrated assessment models  carbon fertilization  climate adaptation  inter-method comparison  
On the long-term changes of drought over China (1948-2012) from different methods of potential evapotranspiration estimations 期刊论文
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2018, 38 (7) : 2954-2966
作者:  Wang, Guojie;  Gong, Tiantian;  Lu, Jiao;  Lou, Dan;  Hagan, Daniel Fiifi T.;  Chen, Tiexi
收藏  |  浏览/下载：17/0  |  提交时间：2019/04/09
climate change  comparison  drought assessment  method  potential evapotranspiration  
Assessing the applicability of WRF optimal parameters under the different precipitation simulations in the Greater Beijing Area 期刊论文
CLIMATE DYNAMICS, 2018, 50: 1927-1948
作者:  Di, Zhenhua;  Duan, Qingyun;  Wang, Chen;  Ye, Aizhong;  Miao, Chiyuan;  Gong, Wei
收藏  |  浏览/下载：14/0  |  提交时间：2019/04/09
Adaptive surrogate model-based optimization method  Parameter optimization  Optimization assessment  Weather Research and Forecasting model  
Mitigation potential of CO2 emissions from modal shift induced by subsidy in hinterland container transport 期刊论文
ENERGY POLICY, 2017, 101
作者:  Tao, Xuezong;  Wu, Qin;  Zhu, Lichao
收藏  |  浏览/下载：5/0  |  提交时间：2019/04/09
Hinterland container transport  Modal shift  CO2 emissions  Random coefficient logit  Semi-life cycle assessment  Activity-based method  
A systematic review of dynamics in climate risk and vulnerability assessments 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2017, 12 (1)
作者:  Jurgilevich, Alexandra;  Rasanen, Aleksi;  Groundstroem, Fanny;  Juhola, Sirkku
收藏  |  浏览/下载：18/0  |  提交时间：2019/04/09
dynamics  climate risk  vulnerability  exposure  assessment method  sub-national  
Methodische Grundlagen des Environment Burden of Disease (EBD)-Ansatzes der WHO zur quantitativen Bewertung von umweltbedingten Krankheitslasten----Chancen; Risiken und Grenzen der Methodik aus naturwissenschaftlicher; rechtlicher und ethischer Perspektive (EBDreview) 科技报告
来源：Ecologic Institute (EU). 出版年： 2015
作者:  Dr. Tanja Srebotnjak;  Lucas Porsch
收藏  |  浏览/下载：33/0  |  提交时间：2019/04/05
Environmental burden of disease  Global Burden of Disease  regional Burden of Disease  DALY  disability weights  exposure-effect-functions  Environmental stressors  Assessment BoD method  Germany