中文版 | English

在结果中检索

GSTDTAP

浏览/检索结果: 共3条，第1-3条 帮助

已选(0)清除 条数/页：   排序方式：
Antagonistic cooperativity between crystal growth modifiers 期刊论文
NATURE, 2020, 577 (7791) : 497-+
作者:  Ma, Wenchuan;  Lutsko, James F.;  Rimer, Jeffrey D.;  Vekilov, Peter G.
收藏  |  浏览/下载：13/0  |  提交时间：2020/07/03

Inhibitor pairs that suppress the crystallization of haematin, which is a part of malaria parasites'  physiology, show unexpected antagonism due to attenuation of step pinning by kink blockers.


Ubiquitous processes in nature and the industry exploit crystallization from multicomponent environments(1-5)  however, laboratory efforts have focused on the crystallization of pure solutes(6,7) and the effects of single growth modifiers(8,9). Here we examine the molecular mechanisms employed by pairs of inhibitors in blocking the crystallization of haematin, which is a model organic compound with relevance to the physiology of malaria parasites(10,11). We use a combination of scanning probe microscopy and molecular modelling to demonstrate that inhibitor pairs, whose constituents adopt distinct mechanisms of haematin growth inhibition, kink blocking and step pinning(12,13), exhibit both synergistic and antagonistic cooperativity depending on the inhibitor combination and applied concentrations. Synergism between two crystal growth modifiers is expected, but the antagonistic cooperativity of haematin inhibitors is not reflected in current crystal growth models. We demonstrate that kink blockers reduce the line tension of step edges, which facilitates both the nucleation of crystal layers and step propagation through the gates created by step pinners. The molecular viewpoint on cooperativity between crystallization modifiers provides guidance on the pairing of modifiers in the synthesis of crystalline materials. The proposed mechanisms indicate strategies to understand and control crystallization in both natural and engineered systems, which occurs in complex multicomponent media(1-3,8,9). In a broader context, our results highlight the complexity of crystal-modifier interactions mediated by the structure and dynamics of the crystal interface.


  
Magnetic control of heterogeneous ice nucleation with nanophase magnetite: Biophysical and agricultural implications 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (21) : 5383-5388
作者:  Kobayashi, Atsuko;  Horikawa, Masamoto;  Kirschvink, Joseph L.;  Golash, Harry N.
收藏  |  浏览/下载：14/0  |  提交时间：2019/11/27
ice crystal nucleation  magnetic supercooling  biogenic magnetite  nanoparticles  food freezing  
Interface Induced Carbonate Mineralization: A Fundamental Geochemical Process Relevant to Carbon Sequestration 科技报告
来源：US Department of Energy (DOE). 出版年： 2013
作者:  Xu, Huifang;  Zhou, Mo;  Zhang, Fangfu;  Konishi, Hiromi;  Shen, Zhizhang;  Teng, H.
收藏  |  浏览/下载：14/0  |  提交时间：2019/04/05
Mica  biotite  muscovite  diopside  tremolite  ultramafic rock  hematite  Ca-Mg-carbonate  calcite  aragonite  dolomite  crystal nucleation  crystallization  interface  catalysis  EBSD  TEM