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Internal state dynamics shape brainwide activity and foraging behaviour 期刊论文
NATURE, 2020, 577 (7789) : 239-+
作者:  Marques, Joao C.;  Li, Meng;  Schaak, Diane;  Robson, Drew N.;  Li, Jennifer M.
收藏  |  浏览/下载:20/0  |  提交时间:2020/07/03

The brain has persistent internal states that can modulate every aspect of an animal'  s mental experience(1-4). In complex tasks such as foraging, the internal state is dynamic(5-8). Caenorhabditis elegans alternate between local search and global dispersal(5). Rodents and primates exhibit trade-offs between exploitation and exploration(6,7). However, fundamental questions remain about how persistent states are maintained in the brain, which upstream networks drive state transitions and how state-encoding neurons exert neuromodulatory effects on sensory perception and decision-making to govern appropriate behaviour. Here, using tracking microscopy to monitor whole-brain neuronal activity at cellular resolution in freely moving zebrafish larvae(9), we show that zebrafish spontaneously alternate between two persistent internal states during foraging for live prey (Paramecia). In the exploitation state, the animal inhibits locomotion and promotes hunting, generating small, localized trajectories. In the exploration state, the animal promotes locomotion and suppresses hunting, generating long-ranging trajectories that enhance spatial dispersion. We uncover a dorsal raphe subpopulation with persistent activity that robustly encodes the exploitation state. The exploitation-state-encoding neurons, together with a multimodal trigger network that is associated with state transitions, form a stochastically activated nonlinear dynamical system. The activity of this oscillatory network correlates with a global retuning of sensorimotor transformations during foraging that leads to marked changes in both the motivation to hunt for prey and the accuracy of motor sequences during hunting. This work reveals an important hidden variable that shapes the temporal structure of motivation and decision-making.


  
A spatial shift-share decomposition of energy consumption changes in China 期刊论文
ENERGY POLICY, 2019, 135
作者:  Lin, Gang;  Jiang, Dong;  Fu, Jingying;  Wang, Di;  Li, Xiang
收藏  |  浏览/下载:16/0  |  提交时间:2020/02/17
Energy consumption  Spatial analysis  Neighborhood effects  Spatial weight matrix  
Revisiting cross-province energy intensity convergence in China: A spatial panel analysis 期刊论文
ENERGY POLICY, 2018, 121: 252-263
作者:  Jiang, Lei;  Folmer, Henk;  Ji, Minhe;  Zhou, P.
收藏  |  浏览/下载:15/0  |  提交时间:2019/04/09
Energy intensity  Convergence  Spatial spillover effects  Spatial econometric model  China  
Carryover effects from natal habitat type upon competitive ability lead to trait divergence or source-sink dynamics 期刊论文
ECOLOGY LETTERS, 2018, 21 (9) : 1341-1352
作者:  Kristensen, Nadiah Pardede;  Johansson, Jacob;  Chisholm, Ryan A.;  Smith, Henrik G.;  Kokko, Hanna
收藏  |  浏览/下载:18/0  |  提交时间:2019/04/09
Developmental effects  ecological speciation  epigenetics  habitat selection  maternal effects  natal effects  natal-habitat preference induction  silver spoon  source-sink  spatial genetic variation  
Climate change accelerates local disease extinction rates in a long-term wild host-pathogen association 期刊论文
GLOBAL CHANGE BIOLOGY, 2018, 24 (8) : 3526-3536
作者:  Zhan, Jiasui;  Ericson, Lars;  Burdon, Jeremy J.
收藏  |  浏览/下载:9/0  |  提交时间:2019/04/09
climate change  epidemiology  extinction  Filipendula ulmaria  longitudinal study  metapopulation  rust  spatial effects  temperature  Triphragmium ulmariae  
Small-scale spatial variability in the distribution of ectomycorrhizal fungi affects plant performance and fungal diversity 期刊论文
ECOLOGY LETTERS, 2017, 20 (9)
作者:  Livne-Luzon, Stav;  Ovadia, Ofer;  Weber, Gil;  Avidan, Yael;  Migael, Hen;  Glassman, Sydney I.;  Bruns, Thomas D.;  Shemesh, Hagai
收藏  |  浏览/下载:14/0  |  提交时间:2019/04/09
Ectomycorrhizal fungi  mutualism  priority effects  spatial heterogeneity  Pinus halepensis  
Planning for green infrastructure: The spatial effects of parks, forests, and fields on Helsinki's apartment prices 期刊论文
ECOLOGICAL ECONOMICS, 2017, 132
作者:  Votsis, Athanasios
收藏  |  浏览/下载:11/0  |  提交时间:2019/04/09
Green infrastructure  Land use options  Spatial effects  Housing prices