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Ice front blocking of ocean heat transport to an Antarctic ice shelf 期刊论文
NATURE, 2020, 578 (7796) : 568-+
作者:  Alexandrov, Ludmil B.;  Kim, Jaegil;  Haradhvala, Nicholas J.;  Huang, Mi Ni;  Ng, Alvin Wei Tian;  Wu, Yang;  Boot, Arnoud;  Covington, Kyle R.;  Gordenin, Dmitry A.;  Bergstrom, Erik N.;  Islam, S. M. Ashiqul;  Lopez-Bigas, Nuria;  Klimczak, Leszek J.;  McPherson, John R.;  Morganella, Sandro;  Sabarinathan, Radhakrishnan;  Wheeler, David A.;  Mustonen, Ville;  Getz, Gad;  Rozen, Steven G.;  Stratton, Michael R.
收藏  |  浏览/下载:52/0  |  提交时间:2020/05/13

The front of the Getz Ice Shelf in West Antarctica creates an abrupt topographic step that deflects ocean currents, suppressing 70% of the heat delivery to the ice sheet.


Mass loss from the Antarctic Ice Sheet to the ocean has increased in recent decades, largely because the thinning of its floating ice shelves has allowed the outflow of grounded ice to accelerate(1,2). Enhanced basal melting of the ice shelves is thought to be the ultimate driver of change(2,3), motivating a recent focus on the processes that control ocean heat transport onto and across the seabed of the Antarctic continental shelf towards the ice(4-6). However, the shoreward heat flux typically far exceeds that required to match observed melt rates(2,7,8), suggesting that other critical controls exist. Here we show that the depth-independent (barotropic) component of the heat flow towards an ice shelf is blocked by the marked step shape of the ice front, and that only the depth-varying (baroclinic) component, which is typically much smaller, can enter the sub-ice cavity. Our results arise from direct observations of the Getz Ice Shelf system and laboratory experiments on a rotating platform. A similar blocking of the barotropic component may occur in other areas with comparable ice-bathymetry configurations, which may explain why changes in the density structure of the water column have been found to be a better indicator of basal melt rate variability than the heat transported onto the continental shelf(9). Representing the step topography of the ice front accurately in models is thus important for simulating ocean heat fluxes and induced melt rates.


  
Mott and generalized Wigner crystal states in WSe2/WS2 moire superlattices 期刊论文
NATURE, 2020, 579 (7799) : 359-+
作者:  Yuan, Jie;  Chang, Si-Yuan;  Yin, Shi-Gang;  Liu, Zhi-Yang;  Cheng, Xiu;  Liu, Xi-Juan;  Jiang, Qiang;  Gao, Ge;  Lin, De-Ying;  Kang, Xin-Lei;  Ye, Shi-Wei;  Chen, Zheng;  Yin, Jiang-An;  Hao, Pei;  Jiang, Lubin;  Cai, Shi-Qing
收藏  |  浏览/下载:82/0  |  提交时间:2020/07/03

Strongly correlated insulating Mott and generalized Wigner phases are detected in WSe2/WS2 moire superlattices, and their electrical properties and excited spin states are studied using an optical technique.


Moire superlattices can be used to engineer strongly correlated electronic states in two-dimensional van der Waals heterostructures, as recently demonstrated in the correlated insulating and superconducting states observed in magic-angle twisted-bilayer graphene and ABC trilayer graphene/boron nitride moire superlattices(1-4). Transition metal dichalcogenide moire heterostructures provide another model system for the study of correlated quantum phenomena(5) because of their strong light-matter interactions and large spin-orbit coupling. However, experimental observation of correlated insulating states in this system is challenging with traditional transport techniques. Here we report the optical detection of strongly correlated phases in semiconducting WSe2/WS2 moire superlattices. We use a sensitive optical detection technique and reveal a Mott insulator state at one hole per superlattice site and surprising insulating phases at 1/3 and 2/3 filling of the superlattice, which we assign to generalized Wigner crystallization on the underlying lattice(6-11). Furthermore, the spin-valley optical selection rules(12-14) of transition metal dichalcogenide heterostructures allow us to optically create and investigate low-energy excited spin states in the Mott insulator. We measure a very long spin relaxation lifetime of many microseconds in the Mott insulating state, orders of magnitude longer than that of charge excitations. Our studies highlight the value of using moire superlattices beyond graphene to explore correlated physics.


  
ATP13A2 deficiency disrupts lysosomal polyamine export 期刊论文
NATURE, 2020, 578 (7795) : 419-+
作者:  Nienhuis, J. H.;  Ashton, A. D.;  Edmonds, D. A.;  Hoitink, A. J. F.;  Kettner, A. J.;  Rowland, J. C.;  Tornqvist, T. E.
收藏  |  浏览/下载:23/0  |  提交时间:2020/07/03

ATP13A2 (PARK9) is a late endolysosomal transporter that is genetically implicated in a spectrum of neurodegenerative disorders, including Kufor-Rakeb syndrome-a parkinsonism with dementia(1)-and early-onset Parkinson'  s disease(2). ATP13A2 offers protection against genetic and environmental risk factors of Parkinson'  s disease, whereas loss of ATP13A2 compromises lysosomes(3). However, the transport function of ATP13A2 in lysosomes remains unclear. Here we establish ATP13A2 as a lysosomal polyamine exporter that shows the highest affinity for spermine among the polyamines examined. Polyamines stimulate the activity of purified ATP13A2, whereas ATP13A2 mutants that are implicated in disease are functionally impaired to a degree that correlates with the disease phenotype. ATP13A2 promotes the cellular uptake of polyamines by endocytosis and transports them into the cytosol, highlighting a role for endolysosomes in the uptake of polyamines into cells. At high concentrations polyamines induce cell toxicity, which is exacerbated by ATP13A2 loss due to lysosomal dysfunction, lysosomal rupture and cathepsin B activation. This phenotype is recapitulated in neurons and nematodes with impaired expression of ATP13A2 or its orthologues. We present defective lysosomal polyamine export as a mechanism for lysosome-dependent cell death that may be implicated in neurodegeneration, and shed light on the molecular identity of the mammalian polyamine transport system.


The lysosomal polyamine transporter ATP13A2 controls the cellular polyamine content, and impaired lysosomal polyamine export represents a lysosome-dependent cell death pathway that may be implicated in ATP13A2-associated neurodegeneration.


  
Star-shaped cities alleviate trade-off between climate change mitigation and adaptation 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2019, 14 (8)
作者:  Pierer, Carl;  Creutzig, Felix
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/27
urban climate solutions  urban economics  climate change mitigation  urban heat island  transport system  linear city  
Effects of anthropogenic nitrogen discharge on dissolved inorganic nitrogen transport in global rivers 期刊论文
GLOBAL CHANGE BIOLOGY, 2019, 25 (4) : 1493-1513
作者:  Liu, Shuang;  Xie, Zhenghui;  Zeng, Yujin;  Liu, Bin;  Li, Ruichao;  Wang, Yan;  Wang, Longhuan;  Qin, Peihua;  Jia, Binghao;  Xie, Jinbo
收藏  |  浏览/下载:23/0  |  提交时间:2019/04/09
earth system model  global biogeochemical cycle  human activities  land surface model  riverine nitrogen transport  water pollution  
Exact Upscaling for Transport of Size-Distributed Colloids 期刊论文
WATER RESOURCES RESEARCH, 2019, 55 (2) : 1011-1039
作者:  Bedrikovetsky, P.;  Osipov, Y.;  Kuzmina, L.;  Malgaresi, G.
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/26
upscaling  averaging  exact averaging of suspension-colloidal and reactive transport with distributed particle properties  reactive transport  exact solutions for 1-D reactive or colloidal flow for the upscaled system  aquifer contamination  
Reaching carbon neutral transport sector in Denmark - Evidence from the incorporation of modal shift into the TIMES energy system modeling framework 期刊论文
ENERGY POLICY, 2018, 113: 571-583
作者:  Tattini, Jacopo;  Gargiulo, Maurizio;  Karlsson, Kenneth
收藏  |  浏览/下载:11/0  |  提交时间:2019/04/09
Modal shift  TIMES model  Integrated Danish energy system  Transport  Behaviour  
Investigating the rebound effect in road transport system: Empirical evidence from China 期刊论文
ENERGY POLICY, 2018, 112: 129-140
作者:  Zhang, Shanshan;  Lin, Boqiang
收藏  |  浏览/下载:19/0  |  提交时间:2019/04/09
China'  s road transport system  Rebound effect  Energy efficiency  Stochastic frontier analysis  Carbon emissions reduction capability  
Final Report: A Model Management System for Numerical Simulations of Subsurface Processes 科技报告
来源:US Department of Energy (DOE). 出版年: 2013
作者:  Zachmann, David
收藏  |  浏览/下载:18/0  |  提交时间:2019/04/05
Mathematical Model  Groundwater  Contaminant Transport Chemical Reactions  Data Mining  Content Management System