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Quantifying overestimated permafrost extent driven by rock glacier inventory 期刊论文
Geophysical Research Letters, 2021
作者:  Bin Cao;  Xin Li;  Min Feng;  Donghai Zheng
收藏  |  浏览/下载:13/0  |  提交时间:2021/04/12
Ultralow‐Frequency Waves in Driving Jovian Aurorae Revealed by Observations from HST and Juno 期刊论文
Geophysical Research Letters, 2021
作者:  Dong‐;  Xiao Pan;  Zhong‐;  Hua Yao;  Harry Manners;  William Dunn;  Bertrand Bonfond;  Denis Grodent;  Bin‐;  Zheng Zhang;  Rui‐;  Long Guo;  Yong Wei
收藏  |  浏览/下载:10/0  |  提交时间:2021/02/17
Rapid Landau heating of Martian topside ionospheric electrons by large‐amplitude magnetosonic waves 期刊论文
Geophysical Research Letters, 2020
作者:  Zhenpeng Su;  Nigang Liu;  Zhonglei Gao;  Bin Wang;  Huinan Zheng;  Yuming Wang;  Shui Wang
收藏  |  浏览/下载:11/0  |  提交时间:2020/10/12
Wintertime particulate matter decrease buffered by unfavorable chemical processes despite emissions reductions in China 期刊论文
Geophysical Research Letters, 2020
作者:  Danny M. Leung;  Hongrong Shi;  Bin Zhao;  Jing Wang;  Elizabeth M. Ding;  Yu Gu;  Haotian Zheng;  Gang Chen;  Kuo‐;  Nan Liou;  Shuxiao Wang;  Jerome D. Fast;  Guangjie Zheng;  Jingkun Jiang;  Xiaoxiao Li;  Jonathan H. Jiang
收藏  |  浏览/下载:13/0  |  提交时间:2020/06/22
An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China 期刊论文
Science, 2020
作者:  Huaiyu Tian;  Yonghong Liu;  Yidan Li;  Chieh-Hsi Wu;  Bin Chen;  Moritz U. G. Kraemer;  Bingying Li;  Jun Cai;  Bo Xu;  Qiqi Yang;  Ben Wang;  Peng Yang;  Yujun Cui;  Yimeng Song;  Pai Zheng;  Quanyi Wang;  Ottar N. Bjornstad;  Ruifu Yang;  Bryan T. Grenfell;  Oliver G. Pybus;  Christopher Dye
收藏  |  浏览/下载:10/0  |  提交时间:2020/05/13
Structure and mechanism of human diacylglycerol O-acyltransferase 1 期刊论文
NATURE, 2020, 581 (7808) : 329-+
作者:  Wu, Fan;  Zhao, Su;  Yu, Bin;  Chen, Yan-Mei;  Wang, Wen;  Song, Zhi-Gang;  Hu, Yi;  Tao, Zhao-Wu;  Tian, Jun-Hua;  Pei, Yuan-Yuan;  Yuan, Ming-Li;  Zhang, Yu-Ling;  Dai, Fa-Hui;  Liu, Yi;  Wang, Qi-Min;  Zheng, Jiao-Jiao;  Xu, Lin;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/03

The structure of human diacylglycerol O-acyltransferase 1, a membrane protein that synthesizes triacylglycerides, is solved with cryo-electron microscopy, providing insight into its function and mechanism of enzymatic activity.


Diacylglycerol O-acyltransferase 1 (DGAT1) synthesizes triacylglycerides and is required for dietary fat absorption and fat storage in humans(1). DGAT1 belongs to the membrane-bound O-acyltransferase (MBOAT) superfamily, members of which are found in all kingdoms of life and are involved in the acylation of lipids and proteins(2,3). How human DGAT1 and other mammalian members of the MBOAT family recognize their substrates and catalyse their reactions is unknown. The absence of three-dimensional structures also hampers rational targeting of DGAT1 for therapeutic purposes. Here we present the cryo-electron microscopy structure of human DGAT1 in complex with an oleoyl-CoA substrate. Each DGAT1 protomer has nine transmembrane helices, eight of which form a conserved structural fold that we name the MBOAT fold. The MBOAT fold in DGAT1 forms a hollow chamber in the membrane that encloses highly conserved catalytic residues. The chamber has separate entrances for each of the two substrates, fatty acyl-CoA and diacylglycerol. DGAT1 can exist as either a homodimer or a homotetramer and the two forms have similar enzymatic activity. The N terminus of DGAT1 interacts with the neighbouring protomer and these interactions are required for enzymatic activity.


  
The online competition between pro- and anti-vaccination views 期刊论文
NATURE, 2020, 582 (7811) : 230-+
作者:  Wu, Fan;  Zhao, Su;  Yu, Bin;  Chen, Yan-Mei;  Wang, Wen;  Song, Zhi-Gang;  Hu, Yi;  Tao, Zhao-Wu;  Tian, Jun-Hua;  Pei, Yuan-Yuan;  Yuan, Ming-Li;  Zhang, Yu-Ling;  Dai, Fa-Hui;  Liu, Yi;  Wang, Qi-Min;  Zheng, Jiao-Jiao;  Xu, Lin;  Holmes, Edward C.;  Zhang, Yong-Zhen
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/03

Insights into the interactions between pro- and anti-vaccination clusters on Facebook can enable policies and approaches that attempt to interrupt the shift to anti-vaccination views and persuade undecided individuals to adopt a pro-vaccination stance.


Distrust in scientific expertise(1-14) is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for example, could amplify outbreaks(2-4), as happened for measles in 2019(5,6). Homemade remedies(7,8) and falsehoods are being shared widely on the Internet, as well as dismissals of expert advice(9-11). There is a lack of understanding about how this distrust evolves at the system level(13,14). Here we provide a map of the contention surrounding vaccines that has emerged from the global pool of around three billion Facebook users. Its core reveals a multi-sided landscape of unprecedented intricacy that involves nearly 100 million individuals partitioned into highly dynamic, interconnected clusters across cities, countries, continents and languages. Although smaller in overall size, anti-vaccination clusters manage to become highly entangled with undecided clusters in the main online network, whereas pro-vaccination clusters are more peripheral. Our theoretical framework reproduces the recent explosive growth in anti-vaccination views, and predicts that these views will dominate in a decade. Insights provided by this framework can inform new policies and approaches to interrupt this shift to negative views. Our results challenge the conventional thinking about undecided individuals in issues of contention surrounding health, shed light on other issues of contention such as climate change(11), and highlight the key role of network cluster dynamics in multi-species ecologies(15).


  
The 30-60-day northward-propagating intraseasonal oscillation over South China Sea during pre-monsoon period in a coupled model 期刊论文
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2019, 39 (12) : 4811-4824
作者:  Zheng, Bin;  Huang, Yanyan;  Li, Chunimi
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
coupled general circulation model  intraseasonal oscillation  northward propagation  pre-monsoon  
Quenching of Equatorial Magnetosonic Waves by Substorm Proton Injections 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2019, 46 (12) : 6156-6167
作者:  Dai, Guyue;  Su, Zhenpeng;  Liu, Nigang;  Wang, Bin;  Zheng, Huinan;  Wang, Yuming;  Wang, Shui
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/26
radiation belt  ring current  wave-particle interaction  magnetosonic wave  Bernstein mode instability  substorm injection  
Mechanisms of Northward-Propagating Intraseasonal Oscillation over the South China Sea during the Pre-Monsoon Period 期刊论文
JOURNAL OF CLIMATE, 2019, 32 (11) : 3297-3311
作者:  Zheng, Bin;  Huang, Yanyan
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/26
Advection  Atmosphere-ocean interaction  Baroclinic flows  Barotropic flows  Intraseasonal variability