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Characterizing Weekly Cycles of Particulate Matter in a Coastal Megacity: The Importance of a Seasonal, Size-Resolved, and Chemically Speciated Analysis 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2020, 125 (13)
作者:  Hilario, Miguel Ricardo A.;  Cruz, Melliza Templonuevo;  Banaga, Paola Angela;  Betito, Grace;  Braun, Rachel A.;  Stahl, Connor;  Cambaliza, Maria Obiminda;  Lorenzo, Genevieve Rose;  MacDonald, Alexander B.;  AzadiAghdam, Mojtaba;  Pabroa, Preciosa Corazon;  Yee, John Robin;  Simpas, James Bernard;  Sorooshian, Armin
收藏  |  浏览/下载:22/0  |  提交时间:2020/08/18
particulate matter  CAMP2EX  weekly cycle  manila  biomass burning  urban emissions  
Potential for large-scale CO2 removal via enhanced rock weathering with croplands 期刊论文
NATURE, 2020, 583 (7815) : 242-+
作者:  David J. Beerling;  Euripides P. Kantzas;  Mark R. Lomas;  Peter Wade;  Rafael M. Eufrasio;  Phil Renforth;  Binoy Sarkar;  M. Grace Andrews;  Rachael H. James;  Christopher R. Pearce;  Jean-Francois Mercure;  Hector Pollitt;  Philip B. Holden;  Neil R. Edwards;  Madhu Khanna;  Lenny Koh;  Shaun Quegan;  Nick F. Pidgeon;  Ivan A. Janssens;  James Hansen;  Steven A. Banwart
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/14

Enhanced silicate rock weathering (ERW), deployable with croplands, has potential use for atmospheric carbon dioxide (CO2) removal (CDR), which is now necessary to mitigate anthropogenic climate change(1). ERW also has possible co-benefits for improved food and soil security, and reduced ocean acidification(2-4). Here we use an integrated performance modelling approach to make an initial techno-economic assessment for 2050, quantifying how CDR potential and costs vary among nations in relation to business-as-usual energy policies and policies consistent with limiting future warming to 2 degrees Celsius(5). China, India, the USA and Brazil have great potential to help achieve average global CDR goals of 0.5 to 2gigatonnes of carbon dioxide (CO2) per year with extraction costs of approximately US$80-180 per tonne of CO2. These goals and costs are robust, regardless of future energy policies. Deployment within existing croplands offers opportunities to align agriculture and climate policy. However, success will depend upon overcoming political and social inertia to develop regulatory and incentive frameworks. We discuss the challenges and opportunities of ERW deployment, including the potential for excess industrial silicate materials (basalt mine overburden, concrete, and iron and steel slag) to obviate the need for new mining, as well as uncertainties in soil weathering rates and land-ocean transfer of weathered products.


  
Low-impact land use pathways to deep decarbonization of electricity 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2020, 15 (7)
作者:  Wu, Grace C.;  Leslie, Emily;  Sawyerr, Oluwafemi;  Cameron, D. Richard;  Brand, Erica;  Cohen, Brian;  Allen, Douglas;  Ochoa, Marcela;  Olson, Arne
收藏  |  浏览/下载:9/0  |  提交时间:2020/08/18
renewable energy  deep decarbonization  land use  conservation  solar energy  wind energy  siting  
Not all driver mutations are equal 期刊论文
NATURE, 2020, 580 (7805) : 595-596
作者:  Legendre, Lucas J.;  Rubilar-Rogers, David;  Musser, Grace M.;  Davis, Sarah N.;  Otero, Rodrigo A.;  Vargas, Alexander O.;  Clarke, Julia A.
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/03

A study of cancer-associated mutations in normal endometrial glands of the uterus has now been performed using whole-genome sequencing. The analysis sheds light on the early changes that lead to invasive disease.


  
Antarctic Surface Mass Balance: Natural Variability, Noise, and Detecting New Trends 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (12)
作者:  King, Matt A.;  Watson, Christopher S.
收藏  |  浏览/下载:9/0  |  提交时间:2020/06/16
Origin of interannual variability in global mean sea level 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (25) : 13983-13990
作者:  Hamlington, Benjamin D.;  Piecuch, Christopher G.;  Reager, John T.;  Chandanpurkar, Hrishi;  Frederikse, Thomas;  Nerem, R. Steven;  Fasullo, John T.;  Cheon, Se-Hyeon
收藏  |  浏览/下载:6/0  |  提交时间:2020/06/16
sea level  climate variability  global mean sea level  satellite altimetry  
Assimilating multi-satellite snow data in ungauged Eurasia improves the simulation accuracy of Asian monsoon seasonal anomalies 期刊论文
ENVIRONMENTAL RESEARCH LETTERS, 2020, 15 (6)
作者:  Lin, Peirong;  Yang, Zong-Liang;  Wei, Jiangfeng;  Dickinson, Robert E.;  Zhang, Yongfei;  Zhao, Long
收藏  |  浏览/下载:10/0  |  提交时间:2020/08/18
Asian monsoon  dynamical seasonal forecast  multi-satellite snow data assimilation  GRACE  MODIS  
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease 期刊论文
NATURE, 2020, 577 (7790) : 399-+
作者:  Gate, David;  Saligrama, Naresha;  Leventhal, Olivia;  Yang, Andrew C.;  Unger, Michael S.;  Middeldorp, Jinte;  Chen, Kelly;  Lehallier, Benoit;  Channappa, Divya;  De Los Santos, Mark B.;  McBride, Alisha;  Pluvinage, John;  Elahi, Fanny;  Tam, Grace Kyin-Ye;  Kim, Yongha;  Greicius, Michael;  Wagner, Anthony D.;  Aigner, Ludwig;  Galasko, Douglas R.;  Davis, Mark M.;  Wyss-Coray, Tony
收藏  |  浏览/下载:6/0  |  提交时间:2020/07/03

Alzheimer'  s disease is an incurable neurodegenerative disorder in which neuroinflammation has a critical function(1). However, little is known about the contribution of the adaptive immune response in Alzheimer'  s disease(2). Here, using integrated analyses of multiple cohorts, we identify peripheral and central adaptive immune changes in Alzheimer'  s disease. First, we performed mass cytometry of peripheral blood mononuclear cells and discovered an immune signature of Alzheimer'  s disease that consists of increased numbers of CD8(+) T effector memory CD45RA(+) (T-EMRA) cells. In a second cohort, we found that CD8(+) T-EMRA cells were negatively associated with cognition. Furthermore, single-cell RNA sequencing revealed that T cell receptor (TCR) signalling was enhanced in these cells. Notably, by using several strategies of single-cell TCR sequencing in a third cohort, we discovered clonally expanded CD8(+) T-EMRA cells in the cerebrospinal fluid of patients with Alzheimer'  s disease. Finally, we used machine learning, cloning and peptide screens to demonstrate the specificity of clonally expanded TCRs in the cerebrospinal fluid of patients with Alzheimer'  s disease to two separate Epstein-Barr virus antigens. These results reveal an adaptive immune response in the blood and cerebrospinal fluid in Alzheimer'  s disease and provide evidence of clonal, antigen-experienced T cells patrolling the intrathecal space of brains affected by age-related neurodegeneration.


  
Anthropogenic and Climate Contributions on the Changes in Terrestrial Water Storage in India 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2020, 125 (10)
作者:  Asoka, Akarsh;  Mishra, Vimal
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/02
VIC  GRACE  TWS  groundwater  drought  
Extending the Global Mass Change Data Record: GRACE Follow-On Instrument and Science Data Performance 期刊论文
GEOPHYSICAL RESEARCH LETTERS, 2020, 47 (12)
作者:  Landerer, Felix W.;  Flechtner, Frank M.;  Save, Himanshu;  Webb, Frank H.;  Bandikova, Tamara;  Bertiger, William, I;  Bettadpur, Srinivas, V;  Byun, Sung Hun;  Dahle, Christoph;  Dobslaw, Henryk;  Fahnestock, Eugene;  Harvey, Nate;  Kang, Zhigui;  Kruizinga, Gerhard L. H.;  Loomis, Bryant D.;  McCullough, Christopher;  Murboeck, Michael;  Nagel, Peter;  Paik, Meegyeong;  Pie, Nadege;  Poole, Steve;  Strekalov, Dmitry;  Tamisiea, Mark E.;  Wang, Furun;  Watkins, Michael M.;  Wen, Hui-Ying;  Wiese, David N.;  Yuan, Dah-Ning
收藏  |  浏览/下载:12/0  |  提交时间:2020/05/25
GRACE-FO  satellite gravimetry  mass change  hydrogeodesy  ice melt  mass transport