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Enhanced growth rate of atmospheric particles from sulfuric acid 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (12) : 7359-7372
作者:  Stolzenburg, Dominik;  Simon, Mario;  Ranjithkumar, Ananth;  Kuerten, Andreas;  Lehtipalo, Katrianne;  Gordon, Hamish;  Ehrhart, Sebastian;  Finkenzeller, Henning;  Pichelstorfer, Lukas;  Nieminen, Tuomo;  He, Xu-Cheng;  Brilke, Sophia;  Xiao, Mao;  Amorim, Antonio;  Baalbaki, Rima;  Baccarini, Andrea;  Beck, Lisa;  Brakling, Steffen;  Murillo, Lucia Caudillo;  Chen, Dexian;  Chu, Biwu;  Dada, Lubna;  Dias, Antonio;  Dommen, Josef;  Duplissy, Jonathan;  El Haddad, Imad;  Fischer, Lukas;  Carracedo, Loic Gonzalez;  Heinritzi, Martin;  Kim, Changhyuk;  Koenig, Theodore K.;  Kong, Weimeng;  Lamkaddam, Houssni;  Lee, Chuan Ping;  Leiminger, Markus;  Li, Zijun;  Makhmutov, Vladimir;  Manninen, Hanna E.;  Marie, Guillaume;  Marten, Ruby;  Mueller, Tatjana;  Nie, Wei;  Partoll, Eva;  Petaja, Tuukka;  Pfeifer, Joschka;  Philippov, Maxim;  Rissanen, Matti P.;  Rorup, Birte;  Schobesberger, Siegfried;  Schuchmann, Simone;  Shen, Jiali;  Sipila, Mikko;  Steiner, Gerhard;  Stozhkov, Yuri;  Tauber, Christian;  Tham, Yee Jun;  Tome, Antonio;  Vazquez-Pufleau, Miguel;  Wagner, Andrea C.;  Wang, Mingyi;  Wang, Yonghong;  Weber, Stefan K.;  Wimmer, Daniela;  Wlasits, Peter J.;  Wu, Yusheng;  Ye, Qing;  Zauner-Wieczorek, Marcel;  Baltensperger, Urs;  Carslaw, Kenneth S.;  Curtius, Joachim;  Donahue, Neil M.;  Flagan, Richard C.;  Hansel, Armin;  Kulmala, Markku;  Lelieveld, Jos;  Volkamer, Rainer;  Kirkby, Jasper;  Winkler, Paul M.
收藏  |  浏览/下载:25/0  |  提交时间:2020/08/18
African climate response to orbital and glacial forcing in 140,000-y simulation with implications for early modern human environments 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (5) : 2255-2264
作者:  Kutzbach, John E.;  Guan, Jian;  He, Feng;  Cohen, Andrew S.;  Orland, Ian J.;  Chen, Guangshan
收藏  |  浏览/下载:15/0  |  提交时间:2020/05/13
paleoclimate  Africa  climate modeling  glacial and orbital forcing  human dispersal  
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds 期刊论文
NATURE, 2020, 580 (7803) : 409-+
作者:  Al-Shayeb, Basem;  Sachdeva, Rohan;  Chen, Lin-Xing;  Ward, Fred;  Munk, Patrick;  Devoto, Audra;  Castelle, Cindy J.;  Olm, Matthew R.;  Bouma-Gregson, Keith;  Amano, Yuki;  He, Christine;  Meheust, Raphael;  Brooks, Brandon;  Thomas, Alex;  Levy, Adi;  Matheus-Carnevali, Paula;  Sun, Christine;  Goltsman, Daniela S. A.;  Borton, Mikayla A.;  Sharrar, Allison;  Jaffe, Alexander L.;  Nelson, Tara C.;  Kantor, Rose;  Keren, Ray;  Lane, Katherine R.;  Farag, Ibrahim F.;  Lei, Shufei;  Finstad, Kari;  Amundson, Ronald;  Anantharaman, Karthik;  Zhou, Jinglie;  Probst, Alexander J.;  Power, Mary E.;  Tringe, Susannah G.;  Li, Wen-Jun;  Wrighton, Kelly;  Harrison, Sue;  Morowitz, Michael;  Relman, David A.;  Doudna, Jennifer A.;  Lehours, Anne-Catherine;  Warren, Lesley;  Cate, Jamie H. D.;  Santini, Joanne M.;  Banfield, Jillian F.
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/03

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent of tuberculosis(1-3). Although Mtb can synthesize vitamin B-12 (cobalamin) de novo, uptake of cobalamin has been linked to pathogenesis of tuberculosis2. Mtb does not encode any characterized cobalamin transporter(4-6)  however, the gene rv1819c was found to be essential for uptake of cobalamin(1). This result is difficult to reconcile with the original annotation of Rv1819c as a protein implicated in the transport of antimicrobial peptides such as bleomycin(7). In addition, uptake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a bacterial ATP-binding cassette (ABC)-exporter fold1. Here, we present structures of Rv1819c, which reveal that the protein indeed contains the ABC-exporter fold, as well as a large water-filled cavity of about 7,700 angstrom(3), which enables the protein to transport the unrelated hydrophilic compounds bleomycin and cobalamin. On the basis of these structures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family, which pump out structurally diverse hydrophobic compounds from cells(8-11).


  
Coherent vortex dynamics in a strongly interacting superfluid on a silicon chip 期刊论文
SCIENCE, 2019, 366 (6472) : 1480-+
作者:  Sachkou, Yauhen P.;  Baker, Christopher G.;  Harris, Glen I.;  Stockdale, Oliver R.;  Forstner, Stefan;  Reeves, Matthew T.;  He, Xin;  McAuslan, David L.;  Bradley, Ashton S.;  Davis, Matthew J.;  Bowen, Warwick P.
收藏  |  浏览/下载:10/0  |  提交时间:2020/02/17
On the Relative Sensitivity of a Tropical Deep Convective Storm to Changes in Environment and Cloud Microphysical Parameters 期刊论文
JOURNAL OF THE ATMOSPHERIC SCIENCES, 2019, 76 (4) : 1163-1185
作者:  Posselt, Derek J.;  He, Fei;  Bukowski, Jennifer;  Reid, Jeffrey S.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/26
Deep convection  Cloud microphysics  Sensitivity studies  Cloud parameterizations  Data assimilation  Ensembles  
The earliest human occupation of the high-altitude Tibetan Plateau 40 thousand to 30 thousand years ago 期刊论文
SCIENCE, 2018, 362 (6418) : 1049-+
作者:  Zhang, X. L.;  Ha, B. B.;  Wang, S. J.;  Chen, Z. J.;  Ge, J. Y.;  Long, H.;  He, W.;  Da, W.;  Nian, X. M.;  Yi, M. J.;  Zhou, X. Y.;  Zhang, P. Q.;  Jin, Y. S.;  Bar-Yosef, O.;  Olsen, J. W.;  Gao, X.
收藏  |  浏览/下载:21/0  |  提交时间:2019/11/27
Rapid change of superconductivity and electron-phonon coupling through critical doping in Bi-2212 期刊论文
SCIENCE, 2018, 362 (6410) : 62-+
作者:  He, Y.;  Hashimoto, M.;  Song, D.;  Chen, S. -D.;  He, J.;  Vishik, I. M.;  Moritz, B.;  Lee, D. -H.;  Nagaosa, N.;  Zaanen, J.;  Devereaux, T. P.;  Yoshida, Y.;  Eisaki, H.;  Lu, D. H.;  Shen, Z. -X.
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27
Scale-invariant magnetoresistance in a cuprate superconductor 期刊论文
SCIENCE, 2018, 361 (6401) : 479-481
作者:  Giraldo-Gallo, P.;  Galvis, J. A.;  Stegen, Z.;  Modic, K. A.;  Balakirev, F. F.;  Betts, J. B.;  Lian, X.;  Moir, C.;  Riggs, S. C.;  Wu, J.;  Bollinger, A. T.;  He, X.;  Bozovic, I.;  Ramshaw, B. J.;  McDonald, R. D.;  Boebinger, G. S.;  Shekhter, A.
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/27
Response to Comment on "Plant diversity increases with the strength of negative density dependence at the global scale" 期刊论文
SCIENCE, 2018, 360 (6391)
作者:  LaManna, Joseph A.;  Mangan, Scott A.;  Alonso, Alfonso;  Bourg, Norman A.;  Brockelman, Warren Y.;  Bunyavejchewin, Sarayudh;  Chang, Li-Wan;  Chiang, Jyh-Min;  Chuyong, George B.;  Clay, Keith;  Cordell, Susan;  Davies, Stuart J.;  Furniss, Tucker J.;  Giardina, Christian P.;  Gunatilleke, I. A. U. Nimal;  Gunatilleke, C. V. Savitri;  He, Fangliang;  Howe, Robert W.;  Hubbell, Stephen P.;  Hsieh, Chang-Fu;  Inman-Narahari, Faith M.;  Janik, David;  Johnson, Daniel J.;  Kenfack, David;  Korte, Lisa;  Kral, Kamil;  Larson, Andrew J.;  Lutz, James A.;  McMahon, Sean M.;  McShea, William J.;  Memiaghe, Herve R.;  Nathalang, Anuttara;  Novotny, Vojtech;  Ong, Perry S.;  Orwig, David A.;  Ostertag, Rebecca;  Parker, Geoffrey G.;  Phillips, Richard P.;  Sack, Lawren;  Sun, I-Fang;  Tello, J. Sebastian;  Thomas, Duncan W.;  Turner, Benjamin L.;  Diaz, Dilys M. Vela;  Vrska, Tomas;  Weiblen, George D.;  Wolf, Amy;  Yap, Sandra;  Myers, Jonathan A.
收藏  |  浏览/下载:18/0  |  提交时间:2019/11/27
Response to Comment on "Plant diversity increases with the strength of negative density dependence at the global scale" 期刊论文
SCIENCE, 2018, 360 (6391)
作者:  LaManna, Joseph A.;  Mangan, Scott A.;  Alonso, Alfonso;  Bourg, Norman A.;  Brockelman, Warren Y.;  Bunyavejchewin, Sarayudh;  Chang, Li-Wan;  Chiang, Jyh-Min;  Chuyong, George B.;  Clay, Keith;  Cordell, Susan;  Davies, Stuart J.;  Furniss, Tucker J.;  Giardina, Christian P.;  Gunatilleke, I. A. U. Nimal;  Gunatilleke, C. V. Savitri;  He, Fangliang;  Howe, Robert W.;  Hubbell, Stephen P.;  Hsieh, Chang-Fu;  Inman-Narahari, Faith M.;  Janik, David;  Johnson, Daniel J.;  Kenfack, David;  Korte, Lisa;  Kral, Kamil;  Larson, Andrew J.;  Lutz, James A.;  McMahon, Sean M.;  McShea, William J.;  Memiaghe, Herve R.;  Nathalang, Anuttara;  Novotny, Vojtech;  Ong, Perry S.;  Orwig, David A.;  Ostertag, Rebecca;  Parker, Geoffrey G.;  Phillips, Richard P.;  Sack, Lawren;  Sun, I-Fang;  Tello, J. Sebastian;  Thomas, Duncan W.;  Turner, Benjamin L.;  Diaz, Dilys M. Vela;  Vrska, Tomas;  Weiblen, George D.;  Wolf, Amy;  Yap, Sandra;  Myers, Jonathan A.
收藏  |  浏览/下载:14/0  |  提交时间:2019/11/27