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Solar geoengineering may not prevent strong warming from direct effects of CO2 on stratocumulus cloud cover 期刊论文
Proceedings of the National Academy of Science, 2020
作者:  Tapio Schneider;  Colleen M. Kaul;  Kyle G. Pressel
收藏  |  浏览/下载:8/0  |  提交时间:2020/11/24
Influx of African biomass burning aerosol during the Amazonian dry season through layered transatlantic transport of black carbon-rich smoke 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (8) : 4757-4785
作者:  Holanda, Bruna A.;  Poehlker, Mira L.;  Walter, David;  Saturno, Jorge;  Soergel, Matthias;  Ditas, Jeannine;  Ditas, Florian;  Schulz, Christiane;  Franco, Marco Aurelio;  Wang, Qiaoqiao;  Donth, Tobias;  Artaxo, Paulo;  Barbosa, Henrique M. J.;  Borrmann, Stephan;  Braga, Ramon;  Brito, Joel;  Cheng, Yafang;  Dollner, Maximilian;  Kaiser, Johannes W.;  Klimach, Thomas;  Knote, Christoph;  Krueger, Ovid O.;  Fuetterer, Daniel;  Lavric, Jost, V;  Ma, Nan;  Machado, Luiz A. T.;  Ming, Jing;  Morais, Fernando G.;  Paulsen, Hauke;  Sauer, Daniel;  Schlager, Hans;  Schneider, Johannes;  Su, Hang;  Weinzierl, Bernadett;  Walser, Adrian;  Wendisch, Manfred;  Ziereis, Helmut;  Zoeger, Martin;  Poeschl, Ulrich;  Andreae, Meinrat O.;  Poehlker, Christopher
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/02
Maximizing and stabilizing luminescence from halide perovskites with potassium passivation (vol 555, pg497, 2018) 期刊论文
NATURE, 2020, 581 (7807) : E1-E1
作者:  Woelfel, Roman;  Corman, Victor M.;  Guggemos, Wolfgang;  Seilmaier, Michael;  Zange, Sabine;  Mueller, Marcel A.;  Niemeyer, Daniela;  Jones, Terry C.;  Vollmar, Patrick;  Rothe, Camilla;  Hoelscher, Michael;  Bleicker, Tobias;  Bruenink, Sebastian;  Schneider, Julia;  Ehmann, Rosina;  Zwirglmaier, Katrin;  Drosten, Christian;  Wendtner, Clemens
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/03

An amendment to this paper has been published and can be accessed via a link at the top of the paper.


  
Multispecific drugs herald a new era of biopharmaceutical innovation 期刊论文
NATURE, 2020, 580 (7803) : 329-338
作者:  Gallego, Laura D.;  Schneider, Maren;  Mittal, Chitvan;  Romanauska, Anete;  Carrillo, Ricardo M. Gudino;  Schubert, Tobias;  Pugh, B. Franklin;  Koehler, Alwin
收藏  |  浏览/下载:31/0  |  提交时间:2020/07/03

The modern biopharmaceutical industry traces its roots to the dawn of the twentieth century, coincident with marketing of aspirin-a signature event in the history of modern drug development. Although the archetypal discovery process did not change markedly in the first seven decades of the industry, the past fifty years have seen two successive waves of transformative innovation in the development of drug molecules: the rise of '  rational drug discovery'  methodology in the 1970s, followed by the invention of recombinant protein-based therapeutic agents in the 1980s. An incipient fourth wave is the advent of multispecific drugs. The successful development of prospectively designed multispecific drugs has the potential to reconfigure our ideas of how target-based therapeutic molecules can work, and what it is possible to achieve with them. Here I review the two major classes of multispecific drugs: those that enrich a therapeutic agent at a particular site of action and those that link a therapeutic target to a biological effector. The latter class-being freed from the constraint of having to directly modulate the target upon binding-may enable access to components of the proteome that currently cannot be targeted by drugs.


  
Trade-offs between multifunctionality and profit in tropical smallholder landscapes 期刊论文
NATURE COMMUNICATIONS, 2020, 11 (1)
作者:  Grass, Ingo;  Kubitza, Christoph;  Krishna, Vijesh V.;  Corre, Marife D.;  Musshoff, Oliver;  Puetz, Peter;  Drescher, Jochen;  Rembold, Katja;  Ariyanti, Eka Sulpin;  Barnes, Andrew D.;  Brinkmann, Nicole;  Brose, Ulrich;  Bruemmer, Bernhard;  Buchori, Damayanti;  Daniel, Rolf;  Darras, Kevin F. A.;  Faust, Heiko;  Fehrmann, Lutz;  Hein, Jonas;  Hennings, Nina;  Hidayat, Purnama;  Hoelscher, Dirk;  Jochum, Malte;  Knohl, Alexander;  Kotowska, Martyna M.;  Krashevska, Valentyna;  Kreft, Holger;  Leuschner, Christoph;  Lobite, Neil Jun S.;  Panjaitan, Rawati;  Polle, Andrea;  Potapov, Anton M.;  Purnama, Edwine;  Qaim, Matin;  Roell, Alexander;  Scheu, Stefan;  Schneider, Dominik;  Tjoa, Aiyen;  Tscharntke, Teja;  Veldkamp, Edzo;  Wollni, Meike
收藏  |  浏览/下载:25/0  |  提交时间:2020/05/13
Thermal history of the Mackenzie Plain, Northwest Territories, Canada: Insights from low-temperature thermochronology of the Devonian Imperial Formation 期刊论文
GEOLOGICAL SOCIETY OF AMERICA BULLETIN, 2020, 132 (3-4) : 767-783
作者:  Powell, Jeremy W.;  Issler, Dale R.;  Schneider, David A.;  Fallas, Karen M.;  Stockli, Daniel F.
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/02
Remote biomass burning dominates southern West African air pollution during the monsoon 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (24) : 15217-15234
作者:  Haslett, Sophie L.;  Taylor, Jonathan W.;  Evans, Mathew;  Morris, Eleanor;  Voge, Bernhard;  Dajuma, Alima;  Brito, Joel;  Batenburg, Anneke M.;  Borrmann, Stephan;  Schneider, Johannes;  Schulz, Christiane;  Denjean, Cyrielle;  Bourrianne, Thierry;  Knippertz, Peter;  Dupuy, Regis;  Schwarzenbock, Alfons;  Sauer, Daniel;  Flamant, Cyrille;  Dorsey, James;  Crawford, Ian;  Coe, Hugh
收藏  |  浏览/下载:19/0  |  提交时间:2020/02/17
Direct determination of mode-projected electron-phonon coupling in the time domain 期刊论文
SCIENCE, 2019, 366 (6470) : 1231-+
作者:  Na, M. X.;  Mills, A. K.;  Boschini, F.;  Michiardi, M.;  Nosarzewski, B.;  Day, R. P.;  Razzoli, E.;  Sheyerman, A.;  Schneider, M.;  Levy, G.;  Zhdanovich, S.;  Devereaux, T. P.;  Kemper, A. F.;  Jones, D. J.;  Damascelli, A.
收藏  |  浏览/下载:7/0  |  提交时间:2020/02/17
Forest restoration: Expanding agriculture 期刊论文
SCIENCE, 2019, 366 (6463) : 316-316
作者:  Delzeit, Ruth;  Pongratz, Julia;  Schneider, Julia M.;  Schuenemann, Franziska;  Mauser, Wolfram;  Zabel, Florian
收藏  |  浏览/下载:10/0  |  提交时间:2019/11/27
A comprehensive characterization of ice nucleation by three different types of cellulose particles immersed in water 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2019, 19 (7) : 4823-4849
作者:  Hiranuma, Naruki;  Adachi, Kouji;  Bell, David M.;  Belosi, Franco;  Beydoun, Hassan;  Bhaduri, Bhaskar;  Bingemer, Heinz;  Budke, Carsten;  Clemen, Hans-Christian;  Conen, Franz;  Cory, Kimberly M.;  Curtius, Joachim;  DeMott, Paul J.;  Eppers, Oliver;  Grawe, Sarah;  Hartmann, Susan;  Hoffmann, Nadine;  Hoehler, Kristina;  Jantsch, Evelyn;  Kiselev, Alexei;  Koop, Thomas;  Kulkarni, Gourihar;  Mayer, Amelie;  Murakami, Masataka;  Murray, Benjamin J.;  Nicosia, Alessia;  Petters, Markus D.;  Piazza, Matteo;  Polen, Michael;  Reicher, Naama;  Rudich, Yinon;  Saito, Atsushi;  Santachiara, Gianni;  Schiebel, Thea;  Schill, Gregg P.;  Schneider, Johannes;  Segev, Lior;  Stopelli, Emiliano;  Sullivan, Ryan C.;  Suski, Kaitlyn;  Szakall, Miklos;  Tajiri, Takuya;  Taylor, Hans;  Tobo, Yutaka;  Ullrich, Romy;  Weber, Daniel;  Wex, Heike;  Whale, Thomas F.;  Whiteside, Craig L.;  Yamashita, Katsuya;  Zelenyuk, Alla;  Moehler, Ottmar
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/26