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An essential role for tungsten in the ecology and evolution of a previously uncultivated lineage of anaerobic, thermophilic Archaea 期刊论文
Nature Communications, 2022
作者:  Buessecker, Steffen;  Palmer, Marike;  Lai, Dengxun;  Dimapilis, Joshua;  Mayali, Xavier;  Mosier, Damon;  Jiao, Jian-Yu;  Colman, Daniel R.;  Keller, Lisa M.;  St. John, Emily;  Miranda, Michelle;  Gonzalez, Cristina;  Gonzalez, Lizett;  Sam, Christian;  Villa, Christopher;  Zhuo, Madeline;  Bodman, Nicholas;  Robles, Fernando;  Boyd, Eric S.;  Cox, Alysia D.;  St. Clair, Brian;  Hua, Zheng-Shuang;  Li, Wen-Jun;  Reysenbach, Anna-Louise;  Stott, Matthew B.;  Weber, Peter K.;  Pett-Ridge, Jennifer;  Dekas, Anne E.;  Hedlund, Brian P.;  Dodsworth, Jeremy A.
收藏  |  浏览/下载:49/0  |  提交时间:2022/07/08
Assessments of the factors controlling latent heat flux and the coupling degree between an alpine wetland and the atmosphere on the Qinghai-Tibetan Plateau in summer 期刊论文
ATMOSPHERIC RESEARCH, 2020, 240
作者:  Chen, Jinlei;  Wen, Jun;  Kang, Shichang;  Meng, Xianhong;  Tian, Hui;  Ma, Xin;  Yuan, Yuan
收藏  |  浏览/下载:31/0  |  提交时间:2020/08/18
Wetlands  Latent heat  Coupling  Control factor  CLM  
A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds 期刊论文
NATURE, 2020, 580 (7803) : 409-+
作者:  Al-Shayeb, Basem;  Sachdeva, Rohan;  Chen, Lin-Xing;  Ward, Fred;  Munk, Patrick;  Devoto, Audra;  Castelle, Cindy J.;  Olm, Matthew R.;  Bouma-Gregson, Keith;  Amano, Yuki;  He, Christine;  Meheust, Raphael;  Brooks, Brandon;  Thomas, Alex;  Levy, Adi;  Matheus-Carnevali, Paula;  Sun, Christine;  Goltsman, Daniela S. A.;  Borton, Mikayla A.;  Sharrar, Allison;  Jaffe, Alexander L.;  Nelson, Tara C.;  Kantor, Rose;  Keren, Ray;  Lane, Katherine R.;  Farag, Ibrahim F.;  Lei, Shufei;  Finstad, Kari;  Amundson, Ronald;  Anantharaman, Karthik;  Zhou, Jinglie;  Probst, Alexander J.;  Power, Mary E.;  Tringe, Susannah G.;  Li, Wen-Jun;  Wrighton, Kelly;  Harrison, Sue;  Morowitz, Michael;  Relman, David A.;  Doudna, Jennifer A.;  Lehours, Anne-Catherine;  Warren, Lesley;  Cate, Jamie H. D.;  Santini, Joanne M.;  Banfield, Jillian F.
收藏  |  浏览/下载:67/0  |  提交时间:2020/07/03

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen and the causative agent of tuberculosis(1-3). Although Mtb can synthesize vitamin B-12 (cobalamin) de novo, uptake of cobalamin has been linked to pathogenesis of tuberculosis2. Mtb does not encode any characterized cobalamin transporter(4-6)  however, the gene rv1819c was found to be essential for uptake of cobalamin(1). This result is difficult to reconcile with the original annotation of Rv1819c as a protein implicated in the transport of antimicrobial peptides such as bleomycin(7). In addition, uptake of cobalamin seems inconsistent with the amino acid sequence, which suggests that Rv1819c has a bacterial ATP-binding cassette (ABC)-exporter fold1. Here, we present structures of Rv1819c, which reveal that the protein indeed contains the ABC-exporter fold, as well as a large water-filled cavity of about 7,700 angstrom(3), which enables the protein to transport the unrelated hydrophilic compounds bleomycin and cobalamin. On the basis of these structures, we propose that Rv1819c is a multi-solute transporter for hydrophilic molecules, analogous to the multidrug exporters of the ABC transporter family, which pump out structurally diverse hydrophobic compounds from cells(8-11).


  
基于ESEF模型的传统农业系统生态足迹测算 项目
项目编号:41801204; 经费:264000(CNY); 起止日期:2019 / dc_date_end
项目负责人:  焦雯珺
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
星载稀疏微波InSAR系统海洋环境探测技术 项目
项目编号:41806211; 经费:260000(CNY); 起止日期:2019 / dc_date_end
项目负责人:  文珺
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
高温钻井液多因素钻具腐蚀性机理及评价方法研究 项目
项目编号:41802196; 经费:200000(CNY); 起止日期:2019 / dc_date_end
项目负责人:  单文军
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/27
Spatial differentiation of heritage trees in the rapidly-urbanizing city of Shenzhen, China 期刊论文
LANDSCAPE AND URBAN PLANNING, 2019, 181: 148-156
作者:  Lai, Po Ying;  Jim, C. Y.;  Da Tang, Guang;  Hong, Wen Jun;  Zhang, Hao
收藏  |  浏览/下载:19/0  |  提交时间:2019/04/09
Heritage tree  Urban tree  Tree habitat  Floristic diversity  Tree conservation  Town plan  
Late spring soil moisture variation over the Tibetan Plateau and its influences on the plateau summer monsoon 期刊论文
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2018, 38 (12) : 4597-4609
作者:  Zhou, Juan;  Wen, Jun;  Liu, Rong;  Wang, Xin;  Xie, Yan
收藏  |  浏览/下载:16/0  |  提交时间:2019/04/09
mechanism  plateau monsoon  soil moisture  Tibetan Plateau  
A Study of Soil Thermal and Hydraulic Properties and Parameterizations for CLM in the SRYR 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2018, 123 (16) : 8487-8499
作者:  Chen, Jinlei;  Wen, Jun;  Tian, Hui;  Zhang, Tangtang;  Yang, Xianyu;  Jia, Dongyu;  Lai, Xin
收藏  |  浏览/下载:17/0  |  提交时间:2019/04/09
Liquid-Vapor-Air Flow in the Frozen Soil 期刊论文
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2018, 123 (14) : 7393-7415
作者:  Yu, Lianyu;  Zeng, Yijian;  Wen, Jun;  Su, Zhongbo
收藏  |  浏览/下载:15/0  |  提交时间:2019/04/09