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X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease 期刊论文
Science, 2021
作者:  Sebastian Günther;  Patrick Y. A. Reinke;  Yaiza Fernández-García;  Julia Lieske;  Thomas J. Lane;  Helen M. Ginn;  Faisal H. M. Koua;  Christiane Ehrt;  Wiebke Ewert;  Dominik Oberthuer;  Oleksandr Yefanov;  Susanne Meier;  Kristina Lorenzen;  Boris Krichel;  Janine-Denise Kopicki;  Luca Gelisio;  Wolfgang Brehm;  Ilona Dunkel;  Brandon Seychell;  Henry Gieseler;  Brenna Norton-Baker;  Beatriz Escudero-Pérez;  Martin Domaracky;  Sofiane Saouane;  Alexandra Tolstikova;  Thomas A. White;  Anna Hänle;  Michael Groessler;  Holger Fleckenstein;  Fabian Trost;  Marina Galchenkova;  Yaroslav Gevorkov;  Chufeng Li;  Salah Awel;  Ariana Peck;  Miriam Barthelmess;  Frank Schlünzen;  P. Lourdu Xavier;  Nadine Werner;  Hina Andaleeb;  Najeeb Ullah;  Sven Falke;  Vasundara Srinivasan;  Bruno Alves França;  Martin Schwinzer;  Hévila Brognaro;  Cromarte Rogers;  Diogo Melo;  Joanna J. Zaitseva-Doyle;  Juraj Knoska;  Gisel E. Peña-Murillo;  Aida Rahmani Mashhour;  Vincent Hennicke;  Pontus Fischer;  Johanna Hakanpää;  Jan Meyer;  Philip Gribbon;  Bernhard Ellinger;  Maria Kuzikov;  Markus Wolf;  Andrea R. Beccari;  Gleb Bourenkov;  David von Stetten;  Guillaume Pompidor;  Isabel Bento;  Saravanan Panneerselvam;  Ivars Karpics;  Thomas R. Schneider;  Maria Marta Garcia-Alai;  Stephan Niebling;  Christian Günther;  Christina Schmidt;  Robin Schubert;  Huijong Han;  Juliane Boger;  Diana C. F. Monteiro;  Linlin Zhang;  Xinyuanyuan Sun;  Jonathan Pletzer-Zelgert;  Jan Wollenhaupt;  Christian G. Feiler;  Manfred S. Weiss;  Eike-Christian Schulz;  Pedram Mehrabi;  Katarina Karničar;  Aleksandra Usenik;  Jure Loboda;  Henning Tidow;  Ashwin Chari;  Rolf Hilgenfeld;  Charlotte Uetrecht;  Russell Cox;  Andrea Zaliani;  Tobias Beck;  Matthias Rarey;  Stephan Günther;  Dusan Turk;  Winfried Hinrichs;  Henry N. Chapman;  Arwen R. Pearson;  Christian Betzel;  Alke Meents
收藏  |  浏览/下载:14/0  |  提交时间:2021/05/14
Tree mode of death and mortality risk factors across Amazon forests 期刊论文
Nature Communications, 2020
作者:  Adriane Esquivel-Muelbert;  Oliver L. Phillips;  Roel J. W. Brienen;  Sophie Fauset;  Martin J. P. Sullivan;  Timothy R. Baker;  Kuo-Jung Chao;  Ted R. Feldpausch;  Emanuel Gloor;  Niro Higuchi;  Jeanne Houwing-Duistermaat;  Jon Lloyd;  Haiyan Liu;  Yadvinder Malhi;  Beatriz Marimon;  Ben Hur Marimon Junior;  Abel Monteagudo-Mendoza;  Lourens Poorter;  Marcos Silveira;  Emilio Vilanova Torre;  Esteban Alvarez Dá;  vila;  Jhon del Aguila Pasquel;  Everton Almeida;  Patricia Alvarez Loayza;  Ana Andrade;  Luiz E. O. C. Aragã;  o;  Alejandro Araujo-Murakami;  Eric Arets;  Luzmila Arroyo;  Gerardo A. Aymard C.;  Michel Baisie;  Christopher Baraloto;  Plí;  nio Barbosa Camargo;  Jorcely Barroso;  Lilian Blanc;  Damien Bonal;  Frans Bongers;  René;  Boot;  Foster Brown;  Benoit Burban;  José;  Luí;  s Camargo;  Wendeson Castro;  Victor Chama Moscoso;  Jerome Chave;  James Comiskey;  Fernando Cornejo Valverde;  Antonio Lola da Costa;  Nallaret Davila Cardozo;  Anthony Di Fiore;  Auré;  lie Dourdain;  Terry Erwin;  Gerardo Flores Llampazo;  Ima Cé;  lia Guimarã;  es Vieira;  Rafael Herrera;  Eurí;  dice Honorio Coronado;  Isau Huamantupa-Chuquimaco;  Eliana Jimenez-Rojas;  Timothy Killeen;  Susan Laurance;  William Laurance;  Aurora Levesley;  Simon L. Lewis;  Karina Liana Lisboa Melgaç;  o Ladvocat;  Gabriela Lopez-Gonzalez;  Thomas Lovejoy;  Patrick Meir;  Casimiro Mendoza;  Paulo Morandi;  David Neill;  Adriano José;  Nogueira Lima;  Percy Nuñ;  ez Vargas;  Edmar Almeida de Oliveira;  Nadir Pallqui Camacho;  Guido Pardo;  Julie Peacock;  Marielos Peñ;  a-Claros;  Maria Cristina Peñ;  uela-Mora;  Georgia Pickavance;  John Pipoly;  Nigel Pitman;  Adriana Prieto;  Thomas A. M. Pugh;  Carlos Quesada;  Hirma Ramirez-Angulo;  Simone Matias de Almeida Reis;  Maxime Rejou-Machain;  Zorayda Restrepo Correa;  Lily Rodriguez Bayona;  Agustí;  n Rudas;  Rafael Salomã;  o;  Julio Serrano;  Javier Silva Espejo;  Natalino Silva;  James Singh;  Clement Stahl;  Juliana Stropp;  Varun Swamy;  Joey Talbot;  Hans ter Steege;  John Terborgh;  Raquel Thomas;  Marisol Toledo;  Armando Torres-Lezama;  Luis Valenzuela Gamarra;  Geertje van der Heijden;  Peter van der Meer;  Peter van der Hout;  Rodolfo Vasquez Martinez;  Simone Aparecida Vieira;  Jeanneth Villalobos Cayo;  Vincent Vos;  Roderick Zagt;  Pieter Zuidema;  David Galbraith
收藏  |  浏览/下载:25/0  |  提交时间:2020/11/20
Asynchronous carbon sink saturation in African and Amazonian tropical forests 期刊论文
NATURE, 2020, 579 (7797) : 80-+
作者:  Wannes Hubau;  Simon L. Lewis;  Oliver L. Phillips;  Kofi Affum-Baffoe;  Hans Beeckman;  Aida Cuní;  -Sanchez;  Armandu K. Daniels;  Corneille E. N. Ewango;  Sophie Fauset;  Jacques M. Mukinzi;  Douglas Sheil;  Bonaventure Sonké;  Martin J. P. Sullivan;  Terry C. H. Sunderland;  Hermann Taedoumg;  Sean C. Thomas;  Lee J. T. White;  Katharine A. Abernethy;  Stephen Adu-Bredu;  Christian A. Amani;  Timothy R. Baker;  Lindsay F. Banin;  Fidè;  le Baya;  Serge K. Begne;  Amy C. Bennett;  Fabrice Benedet;  Robert Bitariho;  Yannick E. Bocko;  Pascal Boeckx;  Patrick Boundja;  Roel J. W. Brienen;  Terry Brncic;  Eric Chezeaux;  George B. Chuyong;  Connie J. Clark;  Murray Collins;  James A. Comiskey;  David A. Coomes;  Greta C. Dargie;  Thales de Haulleville;  Marie Noel Djuikouo Kamdem;  Jean-Louis Doucet;  Adriane Esquivel-Muelbert;  Ted R. Feldpausch;  Alusine Fofanah;  Ernest G. Foli;  Martin Gilpin;  Emanuel Gloor;  Christelle Gonmadje;  Sylvie Gourlet-Fleury;  Jefferson S. Hall;  Alan C. Hamilton;  David J. Harris;  Terese B. Hart;  Mireille B. N. Hockemba;  Annette Hladik;  Suspense A. Ifo;  Kathryn J. Jeffery;  Tommaso Jucker;  Emmanuel Kasongo Yakusu;  Elizabeth Kearsley;  David Kenfack;  Alexander Koch;  Miguel E. Leal;  Aurora Levesley;  Jeremy A. Lindsell;  Janvier Lisingo;  Gabriela Lopez-Gonzalez;  Jon C. Lovett;  Jean-Remy Makana;  Yadvinder Malhi;  Andrew R. Marshall;  Jim Martin;  Emanuel H. Martin;  Faustin M. Mbayu;  Vincent P. Medjibe;  Vianet Mihindou;  Edward T. A. Mitchard;  Sam Moore;  Pantaleo K. T. Munishi;  Natacha Nssi Bengone;  Lucas Ojo;  Fidè;  le Evouna Ondo;  Kelvin S.-H. Peh;  Georgia C. Pickavance;  Axel Dalberg Poulsen;  John R. Poulsen;  Lan Qie;  Jan Reitsma;  Francesco Rovero;  Michael D. Swaine;  Joey Talbot;  James Taplin;  David M. Taylor;  Duncan W. Thomas;  Benjamin Toirambe;  John Tshibamba Mukendi;  Darlington Tuagben;  Peter M. Umunay;  Geertje M. F. van der Heijden;  Hans Verbeeck;  Jason Vleminckx;  Simon Willcock;  Hannsjö;  rg Wö;  ll;  John T. Woods;  Lise Zemagho
收藏  |  浏览/下载:23/0  |  提交时间:2020/05/13

Structurally intact tropical forests sequestered about half of the global terrestrial carbon uptake over the 1990s and early 2000s, removing about 15 per cent of anthropogenic carbon dioxide emissions(1-3). Climate-driven vegetation models typically predict that this tropical forest '  carbon sink'  will continue for decades(4,5). Here we assess trends in the carbon sink using 244 structurally intact African tropical forests spanning 11 countries, compare them with 321 published plots from Amazonia and investigate the underlying drivers of the trends. The carbon sink in live aboveground biomass in intact African tropical forests has been stable for the three decades to 2015, at 0.66 tonnes of carbon per hectare per year (95 per cent confidence interval 0.53-0.79), in contrast to the long-term decline in Amazonian forests(6). Therefore the carbon sink responses of Earth'  s two largest expanses of tropical forest have diverged. The difference is largely driven by carbon losses from tree mortality, with no detectable multi-decadal trend in Africa and a long-term increase in Amazonia. Both continents show increasing tree growth, consistent with the expected net effect of rising atmospheric carbon dioxide and air temperature(7-9). Despite the past stability of the African carbon sink, our most intensively monitored plots suggest a post-2010 increase in carbon losses, delayed compared to Amazonia, indicating asynchronous carbon sink saturation on the two continents. A statistical model including carbon dioxide, temperature, drought and forest dynamics accounts for the observed trends and indicates a long-term future decline in the African sink, whereas the Amazonian sink continues to weaken rapidly. Overall, the uptake of carbon into Earth'  s intact tropical forests peaked in the 1990s. Given that the global terrestrial carbon sink is increasing in size, independent observations indicating greater recent carbon uptake into the Northern Hemisphere landmass(10) reinforce our conclusion that the intact tropical forest carbon sink has already peaked. This saturation and ongoing decline of the tropical forest carbon sink has consequences for policies intended to stabilize Earth'  s climate.


  
Competition drives the decline of a dominant midstorey tree species. Habitat implications for an endangered marsupial 期刊论文
FOREST ECOLOGY AND MANAGEMENT, 2019, 447: 26-34
作者:  Trouve, Raphael;  Nitschke, Craig R.;  Andrieux, Loic;  Willersdorf, Tim;  Robinson, Andrew P.;  Baker, Patrick J.
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/27
Silver wattle  Mountain ash  Acacia dealbata  Leadbeater'  s possum  Gymnobelideus leadbeateri  Habitat suitability  Stand dynamics  Multi-species  Mixed-species  
Identification and structural analysis of the tripartite alpha-pore forming toxin of Aeromonas hydrophila 期刊论文
NATURE COMMUNICATIONS, 2019, 10
作者:  Wilson, Jason S.;  Churchill-Angus, Alicia M.;  Davies, Simon P.;  Sedelnikova, Svetlana E.;  Tzokov, Svetomir B.;  Rafferty, John B.;  Bullough, Per A.;  Bisson, Claudine;  Baker, Patrick J.
收藏  |  浏览/下载:5/0  |  提交时间:2019/11/27
The influence of climate and drought on urban tree growth in southeast Australia and the implications for future growth under climate change 期刊论文
LANDSCAPE AND URBAN PLANNING, 2017, 167
作者:  Nitschke, Craig R.;  Nichols, Scott;  Allen, Kathy;  Dobbs, Cynnamon;  Livesley, Stephen J.;  Baker, Patrick J.;  Lynch, Yvonne
收藏  |  浏览/下载:7/0  |  提交时间:2019/04/09
Climate change  Quercus  Ulmus  Platanus  Drought  Vulnerability  
Estimating the self-thinning line from mortality data 期刊论文
FOREST ECOLOGY AND MANAGEMENT, 2017, 402
作者:  Trouve, Raphael;  Nitschke, Craig R.;  Robinson, Andrew P.;  Baker, Patrick J.
收藏  |  浏览/下载:5/0  |  提交时间:2019/04/09
Self-thinning  Survival  Forest dynamics  Allocation  Allometry  Relative density