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Evaluation of a Wastewater-Based Epidemiological Approach to Estimate the Prevalence of SARS-CoV-2 Infections and the Detection of Viral Variants in Disparate Oregon Communities at City and Neighborhood Scales 期刊论文
Environmental Health Perspectives, 2022
作者:  Blythe A. Layton;  Devrim Kaya;  Christine Kelly;  Kenneth J. Williamson;  Dana Alegre;  Silke M. Bachhuber;  Peter G. Banwarth;  Jeffrey W. Bethel;  Katherine Carter;  Benjamin D. Dalziel;  Mark Dasenko;  Matthew Geniza;  Andrea George;  Anne-Marie Girard;  Roy Haggerty;  Kathryn A. Higley;  Denise M. Hynes;  Jane Lubchenco;  Katherine R. McLaughlin;  F. Javier Nieto;  Aslan Noakes;  Matthew Peterson;  Adriana D. Piemonti;  Justin L. Sanders;  Brett M. Tyler;  Tyler S. Radniecki
收藏  |  浏览/下载:33/0  |  提交时间:2022/07/08
International evaluation of an AI system for breast cancer screening 期刊论文
NATURE, 2020, 577 (7788) : 89-+
作者:  McKinney, Scott Mayer;  Sieniek, Marcin;  Godbole, Varun;  Godwin, Jonathan;  Antropova, Natasha;  Ashrafian, Hutan;  Back, Trevor;  Chesus, Mary;  Corrado, Greg C.;  Darzi, Ara;  Etemadi, Mozziyar;  Garcia-Vicente, Florencia;  Gilbert, Fiona J.;  Halling-Brown, Mark;  Hassabis, Demis;  Jansen, Sunny;  Karthikesalingam, Alan;  Kelly, Christopher J.;  King, Dominic;  Ledsam, Joseph R.;  Melnick, David;  Mostofi, Hormuz;  Peng, Lily;  Reicher, Joshua Jay;  Romera-Paredes, Bernardino;  Sidebottom, Richard;  Suleyman, Mustafa;  Tse, Daniel;  Young, Kenneth C.;  De Fauw, Jeffrey;  Shetty, Shravya
收藏  |  浏览/下载:66/0  |  提交时间:2020/07/03

Screening mammography aims to identify breast cancer at earlier stages of the disease, when treatment can be more successful(1). Despite the existence of screening programmes worldwide, the interpretation of mammograms is affected by high rates of false positives and false negatives(2). Here we present an artificial intelligence (AI) system that is capable of surpassing human experts in breast cancer prediction. To assess its performance in the clinical setting, we curated a large representative dataset from the UK and a large enriched dataset from the USA. We show an absolute reduction of 5.7% and 1.2% (USA and UK) in false positives and 9.4% and 2.7% in false negatives. We provide evidence of the ability of the system to generalize from the UK to the USA. In an independent study of six radiologists, the AI system outperformed all of the human readers: the area under the receiver operating characteristic curve (AUC-ROC) for the AI system was greater than the AUC-ROC for the average radiologist by an absolute margin of 11.5%. We ran a simulation in which the AI system participated in the double-reading process that is used in the UK, and found that the AI system maintained non-inferior performance and reduced the workload of the second reader by 88%. This robust assessment of the AI system paves the way for clinical trials to improve the accuracy and efficiency of breast cancer screening.


  
Cascading effects from plants to soil microorganisms explain how plant species richness and simulated climate change affect soil multifunctionality 期刊论文
GLOBAL CHANGE BIOLOGY, 2018, 24 (12) : 5642-5654
作者:  Valencia, Enrique;  Gross, Nicolas;  Quero, Jose L.;  Carmona, Carlos P.;  Ochoa, Victoria;  Gozalo, Beatriz;  Delgado-Baquerizo, Manuel;  Dumack, Kenneth;  Hamonts, Kelly;  Singh, Brajesh K.;  Bonkowski, Michael;  Maestre, Fernando T.
收藏  |  浏览/下载:32/0  |  提交时间:2019/04/09
bacteria  biodiversity  climate change  ecosystem functioning  environmental filtering  nutrient cycles  protist  species richness  
The Ozone Monitoring Instrument: overview of 14 years in space 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2018, 18 (8) : 5699-5745
作者:  Levelt, Pieternel F.;  Joiner, Joanna;  Tamminen, Johanna;  Veefkind, J. Pepijn;  Bhartia, Pawan K.;  Zweers, Deborah C. Stein;  Duncan, Bryan N.;  Streets, David G.;  Eskes, Henk;  van der A, Ronald;  McLinden, Chris;  Fioletov, Vitali;  Carn, Simon;  de laat, Jos;  DeLand, Matthew;  Marchenko, Sergey;  McPeters, Richard;  Ziemke, Jerald;  Fu, Dejian;  Liu, Xiong;  Pickering, Kenneth;  Apituley, Arnoud;  Abad, Gonzalo Gonzalez;  Arola, Antti;  Boersma, Folkert;  Miller, Christopher Chan;  Chance, Kelly;  de Graaf, Martin;  Hakkarainen, Janne;  Hassinen, Seppo;  Ialongo, Iolanda;  Kleipool, Quintus;  Krotkov, Nickolay;  Li, Can;  Lamsal, Lok;  Newman, Paul;  Nowlan, Caroline;  Suleiman, Raid;  Tilstra, Lieuwe Gijsbert;  Torres, Omar;  Wang, Huiqun;  Wargan, Krzysztof
收藏  |  浏览/下载:43/0  |  提交时间:2019/04/09
EPA GHG Certification of Medium- and Heavy-Duty Vehicles: Development of Road Grade Profiles Representative of US Controlled Access Highways 科技报告
来源:US Department of Energy (DOE). 出版年: 2015
作者:  Wood, Eric;  Duran, Adam;  Burton, Evan;  Gonder, Jeffrey;  Kelly, Kenneth
收藏  |  浏览/下载:12/0  |  提交时间:2019/04/05
United States Environmental Protection Agency  greenhouse gas regulations  medium-duty vehicles  heavy-duty vehicles  road grade  drive cycles