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Haplotype-resolved diverse human genomes and integrated analysis of structural variation 期刊论文
Science, 2021
作者:  Peter Ebert;  Peter A. Audano;  Qihui Zhu;  Bernardo Rodriguez-Martin;  David Porubsky;  Marc Jan Bonder;  Arvis Sulovari;  Jana Ebler;  Weichen Zhou;  Rebecca Serra Mari;  Feyza Yilmaz;  Xuefang Zhao;  PingHsun Hsieh;  Joyce Lee;  Sushant Kumar;  Jiadong Lin;  Tobias Rausch;  Yu Chen;  Jingwen Ren;  Martin Santamarina;  Wolfram Höps;  Hufsah Ashraf;  Nelson T. Chuang;  Xiaofei Yang;  Katherine M. Munson;  Alexandra P. Lewis;  Susan Fairley;  Luke J. Tallon;  Wayne E. Clarke;  Anna O. Basile;  Marta Byrska-Bishop;  André Corvelo;  Uday S. Evani;  Tsung-Yu Lu;  Mark J. P. Chaisson;  Junjie Chen;  Chong Li;  Harrison Brand;  Aaron M. Wenger;  Maryam Ghareghani;  William T. Harvey;  Benjamin Raeder;  Patrick Hasenfeld;  Allison A. Regier;  Haley J. Abel;  Ira M. Hall;  Paul Flicek;  Oliver Stegle;  Mark B. Gerstein;  Jose M. C. Tubio;  Zepeng Mu;  Yang I. Li;  Xinghua Shi;  Alex R. Hastie;  Kai Ye;  Zechen Chong;  Ashley D. Sanders;  Michael C. Zody;  Michael E. Talkowski;  Ryan E. Mills;  Scott E. Devine;  Charles Lee;  Jan O. Korbel;  Tobias Marschall;  Evan E. Eichler
收藏  |  浏览/下载:26/0  |  提交时间:2021/04/06
Detection of two interstellar polycyclic aromatic hydrocarbons via spectral matched filtering 期刊论文
Science, 2021
作者:  Brett A. McGuire;  Ryan A. Loomis;  Andrew M. Burkhardt;  Kin Long Kelvin Lee;  Christopher N. Shingledecker;  Steven B. Charnley;  Ilsa R. Cooke;  Martin A. Cordiner;  Eric Herbst;  Sergei Kalenskii;  Mark A. Siebert;  Eric R. Willis;  Ci Xue;  Anthony J. Remijan;  Michael C. McCarthy
收藏  |  浏览/下载:8/0  |  提交时间:2021/03/29
Fisheries rely on threatened salt marshes 期刊论文
Science, 2020
作者:  Ronald Baker;  Matthew D. Taylor;  Kenneth W. Able;  Michael W. Beck;  Just Cebrian;  Denise D. Colombano;  Rod M. Connolly;  Carolyn Currin;  Linda A. Deegan;  Ilka C. Feller;  Ben L. Gilby;  Matthew E. Kimball;  Thomas J. Minello;  Lawrence P. Rozas;  Charles Simenstad;  R. Eugene Turner;  Nathan J. Waltham;  Michael P. Weinstein;  Shelby L. Ziegler;  Philine S.E. zu Ermgassen;  Caitlin Alcott;  Scott B. Alford;  Myriam A. Barbeau;  Sarah C. Crosby;  Kate Dodds;  Alyssa Frank;  Janelle Goeke;  Lucy A. Goodridge Gaines;  Felicity E. Hardcastle;  Christopher J. Henderson;  W. Ryan James;  Matthew D. Kenworthy;  Justin Lesser;  Debbrota Mallick;  Charles W. Martin;  Ashley E. McDonald;  Catherine McLuckie;  Blair H. Morrison;  James A. Nelson;  Gregory S. Norris;  Jeff Ollerhead;  James W. Pahl;  Sarah Ramsden;  Jennifer S. Rehage;  James F. Reinhardt;  Ryan J. Rezek;  L. Mark Risse;  Joseph A.M. Smith;  Eric L. Sparks;  Lorie W. Staver
收藏  |  浏览/下载:15/0  |  提交时间:2020/11/09
Biomass combustion produces ice-active minerals in biomass-burning aerosol and bottom ash 期刊论文
Proceedings of the National Academy of Science, 2020
作者:  Leif G. Jahn;  Michael J. Polen;  Lydia G. Jahl;  Thomas A. Brubaker;  Joshua Somers;  Ryan C. Sullivan
收藏  |  浏览/下载:8/0  |  提交时间:2020/09/08
An orally available non-nucleotide STING agonist with antitumor activity 期刊论文
Science, 2020
作者:  Bo-Sheng Pan;  Samanthi A. Perera;  Jennifer A. Piesvaux;  Jeremy P. Presland;  Gottfried K. Schroeder;  Jared N. Cumming;  B. Wesley Trotter;  Michael D. Altman;  Alexei V. Buevich;  Brandon Cash;  Saso Cemerski;  Wonsuk Chang;  Yiping Chen;  Peter J. Dandliker;  Guo Feng;  Andrew Haidle;  Timothy Henderson;  James Jewell;  Ilona Kariv;  Ian Knemeyer;  Johnny Kopinja;  Brian M. Lacey;  Jason Laskey;  Charles A. Lesburg;  Rui Liang;  Brian J. Long;  Min Lu;  Yanhong Ma;  Ellen C. Minnihan;  Greg O’Donnell;  Ryan Otte;  Laura Price;  Larissa Rakhilina;  Berengere Sauvagnat;  Sharad Sharma;  Sriram Tyagarajan;  Hyun Woo;  Daniel F. Wyss;  Serena Xu;  David Jonathan Bennett;  George H. Addona
收藏  |  浏览/下载:14/0  |  提交时间:2020/08/25
Global status and conservation potential of reef sharks 期刊论文
Nature, 2020
作者:  M. Aaron MacNeil;  Demian D. Chapman;  Michelle Heupel;  Colin A. Simpfendorfer;  Michael Heithaus;  Mark Meekan;  Euan Harvey;  Jordan Goetze;  Jeremy Kiszka;  Mark E. Bond;  Leanne M. Currey-Randall;  Conrad W. Speed;  C. Samantha Sherman;  Matthew J. Rees;  Vinay Udyawer;  Kathryn I. Flowers;  Gina Clementi;  Jasmine Valentin-Albanese;  Taylor Gorham;  M. Shiham Adam;  Khadeeja Ali;  Fabiá;  n Pina-Amargó;  s;  Jorge A. Angulo-Valdé;  s;  Jacob Asher;  Laura Garcí;  a Barcia;  Océ;  ane Beaufort;  Cecilie Benjamin;  Anthony T. F. Bernard;  Michael L. Berumen;  Stacy Bierwagen;  Erika Bonnema;  Rosalind M. K. Bown;  Darcey Bradley;  Edd Brooks;  J. Jed Brown;  Dayne Buddo;  Patrick Burke;  Camila Cá;  ceres;  Diego Cardeñ;  osa;  Jeffrey C. Carrier;  Jennifer E. Caselle;  Venkatesh Charloo;  Thomas Claverie;  Eric Clua;  Jesse E. M. Cochran;  Neil Cook;  Jessica Cramp;  Brooke D’;  Alberto;  Martin de Graaf;  Mareike Dornhege;  Andy Estep;  Lanya Fanovich;  Naomi F. Farabough;  Daniel Fernando;  Anna L. Flam;  Camilla Floros;  Virginia Fourqurean;  Ricardo Garla;  Kirk Gastrich;  Lachlan George;  Rory Graham;  Tristan Guttridge;  Royale S. Hardenstine;  Stephen Heck;  Aaron C. Henderson;  Heidi Hertler;  Robert Hueter;  Mohini Johnson;  Stacy Jupiter;  Devanshi Kasana;  Steven T. Kessel;  Benedict Kiilu;  Taratu Kirata;  Baraka Kuguru;  Fabian Kyne;  Tim Langlois;  Elodie J. I. Lé;  ;  e;  Steve Lindfield;  Andrea Luna-Acosta;  Jade Maggs;  B. Mabel Manjaji-Matsumoto;  Andrea Marshall;  Philip Matich;  Erin McCombs;  Dianne McLean;  Llewelyn Meggs;  Stephen Moore;  Sushmita Mukherji;  Ryan Murray;  Muslimin Kaimuddin;  Stephen J. Newman;  Josep Nogué;  s;  Clay Obota;  Owen O’;  Shea;  Kennedy Osuka;  Yannis P. Papastamatiou;  Nishan Perera;  Bradley Peterson;  Alessandro Ponzo;  Andhika Prasetyo;  L. M. Sjamsul Quamar;  Jessica Quinlan;  Alexei Ruiz-Abierno;  Enric Sala;  Melita Samoilys;  Michelle Schä;  rer-Umpierre;  Audrey Schlaff;  Nikola Simpson;  Adam N. H. Smith;  Lauren Sparks;  Akshay Tanna;  Rubé;  n Torres;  Michael J. Travers;  Maurits van Zinnicq Bergmann;  Laurent Vigliola;  Juney Ward;  Alexandra M. Watts;  Colin Wen;  Elizabeth Whitman;  Aaron J. Wirsing;  Aljoscha Wothke;  Esteban Zarza-Gonzâ;  lez;  Joshua E. Cinner
收藏  |  浏览/下载:17/0  |  提交时间:2020/08/09
Strong sensitivity of the isotopic composition of methane to the plausible range of tropospheric chlorine 期刊论文
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2020, 20 (14) : 8405-8419
作者:  Strode, Sarah A.;  Wang, James S.;  Manyin, Michael;  Duncan, Bryan;  Hossaini, Ryan;  Keller, Christoph A.;  Michel, Sylvia E.;  White, James W. C.
收藏  |  浏览/下载:17/0  |  提交时间:2020/07/21
COVID-19 recovery can benefit biodiversity 期刊论文
Science, 2020
作者:  Ryan M. Pearson;  Michael Sievers;  Eva C. McClure;  Mischa P. Turschwell;  Rod M. Connolly
收藏  |  浏览/下载:39/0  |  提交时间:2020/05/25
Electrical manipulation of a topological antiferromagnetic state 期刊论文
NATURE, 2020, 580 (7805) : 608-+
作者:  Chabon, Jacob J.;  Hamilton, Emily G.;  Kurtz, David M.;  Esfahani, Mohammad S.;  Moding, Everett J.;  Stehr, Henning;  Schroers-Martin, Joseph;  Nabet, Barzin Y.;  Chen, Binbin;  Chaudhuri, Aadel A.;  Liu, Chih Long;  Hui, Angela B.;  Jin, Michael C.;  Azad, Tej D.;  Almanza, Diego;  Jeon, Young-Jun;  Nesselbush, Monica C.;  Keh, Lyron Co Ting;  Bonilla, Rene F.;  Yoo, Christopher H.;  Ko, Ryan B.;  Chen, Emily L.;  Merriott, David J.;  Massion, Pierre P.;  Mansfield, Aaron S.;  Jen, Jin;  Ren, Hong Z.;  Lin, Steven H.;  Costantino, Christina L.;  Burr, Risa;  Tibshirani, Robert;  Gambhir, Sanjiv S.;  Berry, Gerald J.;  Jensen, Kristin C.;  West, Robert B.;  Neal, Joel W.;  Wakelee, Heather A.;  Loo, Billy W., Jr.;  Kunder, Christian A.;  Leung, Ann N.;  Lui, Natalie S.;  Berry, Mark F.;  Shrager, Joseph B.;  Nair, Viswam S.;  Haber, Daniel A.;  Sequist, Lecia V.;  Alizadeh, Ash A.;  Diehn, Maximilian
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/03

Room-temperature electrical switching of a topological antiferromagnetic state in polycrystalline Mn3Sn thin films is demonstrated using the same protocol as that used for conventional ferromagnetic metals.


Electrical manipulation of phenomena generated by nontrivial band topology is essential for the development of next-generation technology using topological protection. A Weyl semimetal is a three-dimensional gapless system that hosts Weyl fermions as low-energy quasiparticles(1-4). It has various exotic properties, such as a large anomalous Hall effect (AHE) and chiral anomaly, which are robust owing to the topologically protected Weyl nodes(1-16). To manipulate such phenomena, a magnetic version of Weyl semimetals would be useful for controlling the locations of Weyl nodes in the Brillouin zone. Moreover, electrical manipulation of antiferromagnetic Weyl metals would facilitate the use of antiferromagnetic spintronics to realize high-density devices with ultrafast operation(17,18). However, electrical control of a Weyl metal has not yet been reported. Here we demonstrate the electrical switching of a topological antiferromagnetic state and its detection by the AHE at room temperature in a polycrystalline thin film(19) of the antiferromagnetic Weyl metal Mn3Sn9,10,12,20, which exhibits zero-field AHE. Using bilayer devices composed of Mn3Sn and nonmagnetic metals, we find that an electrical current density of about 10(10) to 10(11) amperes per square metre induces magnetic switching in the nonmagnetic metals, with a large change in Hall voltage. In addition, the current polarity along the bias field and the sign of the spin Hall angle of the nonmagnetic metals-positive for Pt (ref. (21)), close to 0 for Cu and negative for W (ref. (22))-determines the sign of the Hall voltage. Notably, the electrical switching in the antiferromagnet is achieved with the same protocol as that used for ferromagnetic metals(23,24). Our results may lead to further scientific and technological advances in topological magnetism and antiferromagnetic spintronics.


  
Highly porous nature of a primitive asteroid revealed by thermal imaging 期刊论文
NATURE, 2020, 579 (7800) : 518-522
作者:  Quinn, Robert A.;  Melnik, Alexey, V;  Vrbanac, Alison;  Fu, Ting;  Patras, Kathryn A.;  Christy, Mitchell P.;  Bodai, Zsolt;  Belda-Ferre, Pedro;  Tripathi, Anupriya;  Chung, Lawton K.;  Downes, Michael;  Welch, Ryan D.;  Quinn, Melissa;  Humphrey, Greg;  Panitchpakdi, Morgan;  Weldon, Kelly C.;  Aksenov, Alexander;  da Silva, Ricardo;  Avila-Pacheco, Julian;  Clish, Clary;  Bae, Sena;  Mallick, Himel;  Franzosa, Eric A.;  Lloyd-Price, Jason;  Bussell, Robert;  Thron, Taren;  Nelson, Andrew T.;  Wang, Mingxun;  Leszczynski, Eric;  Vargas, Fernando;  Gauglitz, Julia M.;  Meehan, Michael J.;  Gentry, Emily;  Arthur, Timothy D.;  Komor, Alexis C.;  Poulsen, Orit;  Boland, Brigid S.;  Chang, John T.;  Sandborn, William J.;  Lim, Meerana;  Garg, Neha;  Lumeng, Julie C.;  Xavier, Ramnik J.;  Kazmierczak, Barbara, I;  Jain, Ruchi;  Egan, Marie;  Rhee, Kyung E.;  Ferguson, David;  Raffatellu, Manuela;  Vlamakis, Hera;  Haddad, Gabriel G.;  Siegel, Dionicio;  Huttenhower, Curtis;  Mazmanian, Sarkis K.;  Evans, Ronald M.;  Nizet, Victor;  Knight, Rob;  Dorrestein, Pieter C.
收藏  |  浏览/下载:50/0  |  提交时间:2020/05/13

Carbonaceous (C-type) asteroids(1) are relics of the early Solar System that have preserved primitive materials since their formation approximately 4.6 billion years ago. They are probably analogues of carbonaceous chondrites(2,3) and are essential for understanding planetary formation processes. However, their physical properties remain poorly known because carbonaceous chondrite meteoroids tend not to survive entry to Earth'  s atmosphere. Here we report on global one-rotation thermographic images of the C-type asteroid 162173 Ryugu, taken by the thermal infrared imager (TIR)(4) onboard the spacecraft Hayabusa2(5), indicating that the asteroid'  s boulders and their surroundings have similar temperatures, with a derived thermal inertia of about 300 J m(-2) s(-0.5) K-1 (300 tiu). Contrary to predictions that the surface consists of regolith and dense boulders, this low thermal inertia suggests that the boulders are more porous than typical carbonaceous chondrites(6) and that their surroundings are covered with porous fragments more than 10 centimetres in diameter. Close-up thermal images confirm the presence of such porous fragments and the flat diurnal temperature profiles suggest a strong surface roughness effect(7,8). We also observed in the close-up thermal images boulders that are colder during the day, with thermal inertia exceeding 600 tiu, corresponding to dense boulders similar to typical carbonaceous chondrites(6). These results constrain the formation history of Ryugu: the asteroid must be a rubble pile formed from impact fragments of a parent body with microporosity(9) of approximately 30 to 50 per cent that experienced a low degree of consolidation. The dense boulders might have originated from the consolidated innermost region or they may have an exogenic origin. This high-porosity asteroid may link cosmic fluffy dust to dense celestial bodies(10).


Thermal imaging data obtained from the spacecraft Hayabusa2 reveal that the carbonaceous asteroid 162173 Ryugu is an object of unusually high porosity.